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Murcko scaffold

Ring system with 4 rings and 22 atoms

28 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
28
With full pages
1
Scaffold SMILES

c1ccc(C2CCc3ccccc3C2c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(C2CCc3ccccc3C2c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

1-Naphthol, 1,2,3,4-tetrahydro-1-(p-(2-(diethylamino)ethoxy)phenyl)-2-phenyl-, hydrochloride chemical structure, C28H34ClNO2, CAS 1820-38-8
1-Naphthol, 1,2,3,4-tetrahydro-1-(p-(2-(diethylamino)ethoxy)phenyl)-2-phenyl-, hydrochloride
CAS 1820-38-8C28H34ClNO2
1,2,3,4-Tetrahydro-1,2-diphenyl-6-methoxy-1-naphthol chemical structure, C23H22O2, CAS 4256-35-3
1,2,3,4-Tetrahydro-1,2-diphenyl-6-methoxy-1-naphthol
CAS 4256-35-3C23H22O2
6-Methoxy-2-phenyl-1-(p-tolyl)-1,2,3,4-tetrahydro-1-naphthol chemical structure, C24H24O2, CAS 4256-36-4
6-Methoxy-2-phenyl-1-(p-tolyl)-1,2,3,4-tetrahydro-1-naphthol
CAS 4256-36-4C24H24O2
1,2,3,4-Tetrahydro-1-(p-fluorophenyl)-6-methoxy-2-phenyl-1-naphthol chemical structure, C23H21FO2, CAS 4310-62-7
1,2,3,4-Tetrahydro-1-(p-fluorophenyl)-6-methoxy-2-phenyl-1-naphthol
CAS 4310-62-7C23H21FO2
Diethylamine, 2-(p-(2-(p-chlorophenyl)-1,2,3,4-tetrahydro-1-naphthyl)phenoxy)-, hydrochloride chemical structure, C26H29Cl2NO, CAS 13972-33-3
Diethylamine, 2-(p-(2-(p-chlorophenyl)-1,2,3,4-tetrahydro-1-naphthyl)phenoxy)-, hydrochloride
CAS 13972-33-3C26H29Cl2NO
2-[4-[2-(4-Chlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]phenoxy]-N,N-diethylethanamine chemical structure, C28H32ClNO, CAS 13073-86-4
2-[4-[2-(4-Chlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]phenoxy]-N,N-diethylethanamine
CAS 13073-86-4C28H32ClNO
cis-(3-(p-(1,2,3,4-Tetrahydro-6-methoxy-2-phenyl-1-naphthyl)phenoxy))-1,2-propanediol chemical structure, C26H28O4, CAS 36840-93-4
cis-(3-(p-(1,2,3,4-Tetrahydro-6-methoxy-2-phenyl-1-naphthyl)phenoxy))-1,2-propanediol
CAS 36840-93-4C26H28O4
2-(p-(2-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthyl)phenoxy)triethylamine hydrochloride chemical structure, C28H32Cl3NO, CAS 4796-82-1
2-(p-(2-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthyl)phenoxy)triethylamine hydrochloride
CAS 4796-82-1C28H32Cl3NO
2-(p-(2-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthyl)phenoxy)triethylamine chemical structure, C28H31Cl2NO, CAS 13085-36-4
2-(p-(2-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthyl)phenoxy)triethylamine
CAS 13085-36-4C28H31Cl2NO
Triethylamine, 2-(p-(2-phenyl-1,2,3,4-tetrahydro-1-naphthyl)phenoxy)-, (E)- chemical structure, C28H33NO, CAS 4800-52-6
Triethylamine, 2-(p-(2-phenyl-1,2,3,4-tetrahydro-1-naphthyl)phenoxy)-, (E)-
CAS 4800-52-6C28H33NO
Triethylamine, 2-(p-(2-phenyl-1,2,3,4-tetrahydro-1-naphthyl)phenoxy)-, (Z)- chemical structure, C28H33NO, CAS 4827-61-6
Triethylamine, 2-(p-(2-phenyl-1,2,3,4-tetrahydro-1-naphthyl)phenoxy)-, (Z)-
CAS 4827-61-6C28H33NO
trans-2-(p-(2-(p-Chlorophenyl)-1,2,3,4-tetrahydro-1-naphthyl)phenoxy)triethylamine chemical structure, C28H32ClNO, CAS 602-54-0
trans-2-(p-(2-(p-Chlorophenyl)-1,2,3,4-tetrahydro-1-naphthyl)phenoxy)triethylamine
CAS 602-54-0C28H32ClNO
Triethylamine, 2-(p-(6-methoxy-2-phenyl-1,2,3,4-tetrahydro-1-naphthyl)phenoxy)-, hydrochloride, (E)- chemical structure, C29H36ClNO2, CAS 13073-58-0
Triethylamine, 2-(p-(6-methoxy-2-phenyl-1,2,3,4-tetrahydro-1-naphthyl)phenoxy)-, hydrochloride, (E)-
CAS 13073-58-0C29H36ClNO2
Triethylamine, 2-(p-(2-(p-methoxyphenyl)-1,2,3,4-tetrahydro-1-naphthyl)phenoxy)-, citrate, monohydrate chemical structure, C29H35NO2, CAS 13073-90-0
Triethylamine, 2-(p-(2-(p-methoxyphenyl)-1,2,3,4-tetrahydro-1-naphthyl)phenoxy)-, citrate, monohydrate
CAS 13073-90-0C29H35NO2
2-(p-(2-(o-Fluorophenyl)-1,2,3,4-tetrahydro-1-naphthyl)phenoxy)triethylamine citrate chemical structure, C34H40FNO8, CAS 13754-17-1
2-(p-(2-(o-Fluorophenyl)-1,2,3,4-tetrahydro-1-naphthyl)phenoxy)triethylamine citrate
CAS 13754-17-1C34H40FNO8
N,N-Diethyl-2-(4-(2-(2-fluorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy)ethan-1-amine chemical structure, C28H32FNO, CAS 13073-92-2
N,N-Diethyl-2-(4-(2-(2-fluorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy)ethan-1-amine
CAS 13073-92-2C28H32FNO
2-(p-(2-(p-Chlorophenyl)-1,2,3,4-tetrahydro-6-methoxy-1-naphthyl)phenoxy)triethylamine, hydrochloride chemical structure, C29H35Cl2NO2, CAS 13972-34-4
2-(p-(2-(p-Chlorophenyl)-1,2,3,4-tetrahydro-6-methoxy-1-naphthyl)phenoxy)triethylamine, hydrochloride
CAS 13972-34-4C29H35Cl2NO2
2-(4-(2-(4-Chlorophenyl)-6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy)-N,N-diethylethanamine chemical structure, C29H34ClNO2, CAS 13729-33-4
2-(4-(2-(4-Chlorophenyl)-6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy)-N,N-diethylethanamine
CAS 13729-33-4C29H34ClNO2
Triethylamine, 2-(p-(2-(p-chlorophenyl)-2-methyl-1,2,3,4-tetrahydro-1-naphthyl)phenoxy)-, hydrochloride chemical structure, C29H35Cl2NO, CAS 15065-14-2
Triethylamine, 2-(p-(2-(p-chlorophenyl)-2-methyl-1,2,3,4-tetrahydro-1-naphthyl)phenoxy)-, hydrochloride
CAS 15065-14-2C29H35Cl2NO
cis-4-(1,2,3,4-Tetrahydro-6-methoxy-2-phenyl-1-naphthalenyl)phenol chemical structure, C23H22O2, CAS 14089-22-6
cis-4-(1,2,3,4-Tetrahydro-6-methoxy-2-phenyl-1-naphthalenyl)phenol
CAS 14089-22-6C23H22O2
1,2,3,4-Tetrahydro-1-(4-methoxyphenyl)-2-phenylnaphthalene chemical structure, C23H22O, CAS 4796-76-3
1,2,3,4-Tetrahydro-1-(4-methoxyphenyl)-2-phenylnaphthalene
CAS 4796-76-3C23H22O
4-((1R,2S)-6-(tert-Butoxy)-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenyl 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate chemical structure, C30H27F9O4S, CAS 2229713-97-5
4-((1R,2S)-6-(tert-Butoxy)-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenyl 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate
CAS 2229713-97-5C30H27F9O4S
4-(6-(tert-Butoxy)-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenol chemical structure, C26H28O2, CAS 2741696-03-5
4-(6-(tert-Butoxy)-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenol
CAS 2741696-03-5C26H28O2
4-((1R,2S)-6-(tert-Butoxy)-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenol chemical structure, C26H28O2, CAS 2229713-95-3
4-((1R,2S)-6-(tert-Butoxy)-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenol
CAS 2229713-95-3C26H28O2