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Murcko scaffold

Ring system with 4 rings and 18 atoms

18 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
18
Chemicals
18
With full pages
6
Scaffold SMILES

O=C1C=CC23CCNCc4cccc(c42)OC3C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=CC23CCNCc4cccc(c42)OC3C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

(+)-Narwedine chemical structure, C17H19NO3, CAS 7318-55-0
(+)-Narwedine
CAS 7318-55-0C17H19NO3
Galanthaminon chemical structure, C17H19NO3, CAS 1668-86-6
Galanthaminon
CAS 1668-86-6C17H19NO3
(12R)-9-Methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-one chemical structure, C17H19NO3
(12R)-9-Methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-one
C17H19NO3
1-Bromo-3-methoxy-6-oxo-4a,5,9,10-tetrahydro-6H-benzo[2,3]benzofuro[4,3-cd]azepine-11(12H)-carbaldehyde chemical structure, C17H16BrNO4, CAS 252869-09-3
1-Bromo-3-methoxy-6-oxo-4a,5,9,10-tetrahydro-6H-benzo[2,3]benzofuro[4,3-cd]azepine-11(12H)-carbaldehyde
CAS 252869-09-3C17H16BrNO4
Narwedine chemical structure, C17H19NO3, CAS 510-77-0
Narwedine
CAS 510-77-0C17H19NO3
N-Demethylnarwedine chemical structure, C16H17NO3, CAS 216986-48-0
N-Demethylnarwedine
CAS 216986-48-0C16H17NO3
rel-(4aR,8aR)-1-Bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one chemical structure, C17H18BrNO3, CAS 183487-56-1
rel-(4aR,8aR)-1-Bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one
CAS 183487-56-1C17H18BrNO3
(1S,12S)-7-Bromo-9-methoxy-14-oxo-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6,8,10(17),15-tetraene-4-carbaldehyde chemical structure, C17H16BrNO4, CAS 122584-14-9
(1S,12S)-7-Bromo-9-methoxy-14-oxo-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6,8,10(17),15-tetraene-4-carbaldehyde
CAS 122584-14-9C17H16BrNO4
Galanthamine impurity 19 chemical structure, C16H16BrNO3, CAS 261961-54-0
Galanthamine impurity 19
CAS 261961-54-0C16H16BrNO3
7,15-Dibromo-8-methoxy-14-oxo-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraene-4-carbaldehyde chemical structure, C17H15Br2NO4, CAS 1076198-20-3
7,15-Dibromo-8-methoxy-14-oxo-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraene-4-carbaldehyde
CAS 1076198-20-3C17H15Br2NO4
(±)-Narwedine chemical structure, C17H19NO3
(±)-Narwedine
C17H19NO3
(1S)-7-Bromo-8-methoxy-14-oxo-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraene-4-carbaldehyde chemical structure, C17H16BrNO4, CAS 1391047-97-4
(1S)-7-Bromo-8-methoxy-14-oxo-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraene-4-carbaldehyde
CAS 1391047-97-4C17H16BrNO4
Galanthaminone hydrobromide chemical structure, C17H20BrNO3, CAS 690959-38-7
Galanthaminone hydrobromide
CAS 690959-38-7C17H20BrNO3
Galanthaminone hydrobromide chemical structure, C17H20BrNO3
Galanthaminone hydrobromide
C17H20BrNO3
(1R,12R)-7-Bromo-9-methoxy-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6,8,10(17),15-tetraen-14-one chemical structure, C16H16BrNO3, CAS 179108-06-6
(1R,12R)-7-Bromo-9-methoxy-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6,8,10(17),15-tetraen-14-one
CAS 179108-06-6C16H16BrNO3
(1S,12R)-9-Methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-one chemical structure, C17H19NO3
(1S,12R)-9-Methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-one
C17H19NO3
Galanthaminone hydrobromide chemical structure, C17H20BrNO3
Galanthaminone hydrobromide
C17H20BrNO3
6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-one, 1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-, hydrochloride (1:1), (4aR,8aR)- chemical structure, C16H17BrClNO3, CAS 1434055-68-1
6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-one, 1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-, hydrochloride (1:1), (4aR,8aR)-
CAS 1434055-68-1C16H17BrClNO3