Murcko scaffold
Ring system with 2 rings and 14 atoms
36 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 36
- With full pages
- 7
Scaffold SMILES
N=C(c1ccccc1)c1ccccn1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 36 of 36 chemicals
Phenyl 2-pyridyl ketone oxime
C12H10N2O
Phenyl 2-pyridyl ketone hydrazone
C12H11N3
2-Benzoylpyridine thiosemicarbazone
CAS 82766-13-0C13H12N4S
(E)-Methyl 2-(phenyl(pyridin-2-yl)methylene)hydrazinecarbodithioate
CAS 26158-28-1C14H13N3S2
![[(E)-[[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-phenylmethylidene]amino]urea chemical structure, C14H10ClF3N4O, CAS 251310-67-5](/s/HCMZEAIMLAJJPB-SRZZPIQSSA-N.svg)
[(E)-[[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-phenylmethylidene]amino]urea
CAS 251310-67-5C14H10ClF3N4O
![(E)-[[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-(4-nitrophenyl)methylidene]hydrazine chemical structure, C13H8ClF3N4O2, CAS 339010-52-5](/s/IBCIESJDAALVFR-RGVLZGJSSA-N.svg)
(E)-[[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-(4-nitrophenyl)methylidene]hydrazine
CAS 339010-52-5C13H8ClF3N4O2
![(E)-[Phenyl(pyridin-2-yl)methylidene]hydrazine chemical structure, C12H11N3, CAS 56009-91-7](/s/NPIHYGZWEUGMNG-NTCAYCPXSA-N.svg)
(E)-[Phenyl(pyridin-2-yl)methylidene]hydrazine
CAS 56009-91-7C12H11N3
![1,1-Dimethyl-3-[(Z)-[phenyl(pyridin-2-yl)methylidene]amino]thiourea chemical structure, C15H16N4S](/s/KUHVCGKIRQEOHA-VKAVYKQESA-N.svg)
1,1-Dimethyl-3-[(Z)-[phenyl(pyridin-2-yl)methylidene]amino]thiourea
C15H16N4S
![[(E)-[[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-(2,4-dichlorophenyl)methylidene]amino]urea chemical structure, C14H8Cl3F3N4O, CAS 338770-48-2](/s/GTFLTGJKRKNQSD-FOKLQQMPSA-N.svg)
[(E)-[[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-(2,4-dichlorophenyl)methylidene]amino]urea
CAS 338770-48-2C14H8Cl3F3N4O
Ketone, phenyl 2-pyridyl, O-(2-(diethylamino)ethyl)oxime
CAS 14143-64-7C18H23N3O
(Z)-Phenyl(2-pyridinyl)methanone semicarbazone
CAS 74833-48-0C13H12N4O
2-(Phenylmethanehydrazonoyl)pyridine
C12H11N3
![N,N-Dimethyl-2-[phenyl(pyridin-2-yl)methylidene]hydrazinecarbothioamide chemical structure, C15H16N4S, CAS 152094-66-1](/s/KUHVCGKIRQEOHA-SAPNQHFASA-N.svg)
N,N-Dimethyl-2-[phenyl(pyridin-2-yl)methylidene]hydrazinecarbothioamide
CAS 152094-66-1C15H16N4S
Benzenamine, 4-bromo-2-(imino-2-pyridinylmethyl)-
CAS 62375-31-9C12H10BrN3
4-Methyl-I+/--phenyl-2-pyridinemethanimine
CAS 18103-76-9C13H12N2
![2-[(4-Fluorophenyl)(hydrazono)methyl]pyridine chemical structure, C12H10FN3, CAS 1613186-48-3](/s/XDMDGBWDFZHCIS-UHFFFAOYSA-N.svg)
2-[(4-Fluorophenyl)(hydrazono)methyl]pyridine
CAS 1613186-48-3C12H10FN3
![2-[(3-Bromophenyl)(hydrazono)methyl]pyridine chemical structure, C12H10BrN3, CAS 1613186-49-4](/s/ICOVAZBAVUILGO-UHFFFAOYSA-N.svg)
2-[(3-Bromophenyl)(hydrazono)methyl]pyridine
CAS 1613186-49-4C12H10BrN3
![2-[(2-Chlorophenyl)(hydrazono)methyl]pyridine chemical structure, C12H10ClN3, CAS 78539-97-6](/s/BTCXVIAEWABPQG-UHFFFAOYSA-N.svg)
2-[(2-Chlorophenyl)(hydrazono)methyl]pyridine
CAS 78539-97-6C12H10ClN3
Methanone, phenyl-2-pyridinyl-, oxime
CAS 1826-28-4C12H10N2O
Phenyl 2-pyridyl ketoxime
CAS 14178-30-4C12H10N2O
methanone oxime chemical structure, C14H10ClF3N2O2, CAS 339106-69-3](/s/LXICDQJULNKEHC-UDWIEESQSA-N.svg)
[3-Chloro-5-(trifluoromethyl)-2-pyridinyl](4-methoxyphenyl)methanone oxime
CAS 339106-69-3C14H10ClF3N2O2
methanone oxime chemical structure, C13H6Cl3F3N2O, CAS 339106-22-8](/s/VZCLLMDAMDVQMG-SRZZPIQSSA-N.svg)
[3-Chloro-5-(trifluoromethyl)-2-pyridinyl](2,4-dichlorophenyl)methanone oxime
CAS 339106-22-8C13H6Cl3F3N2O
![(4-Chlorophenyl)[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methanone oxime chemical structure, C13H7Cl2F3N2O, CAS 338960-05-7](/s/FYOHMKXNOOSMNU-RGVLZGJSSA-N.svg)
(4-Chlorophenyl)[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methanone oxime
CAS 338960-05-7C13H7Cl2F3N2O
methanone oxime chemical structure, C13H8ClF3N2O, CAS 251096-60-3](/s/ODQQPURTMHCYAS-YBFXNURJSA-N.svg)
[3-Chloro-5-(trifluoromethyl)-2-pyridinyl](phenyl)methanone oxime
CAS 251096-60-3C13H8ClF3N2O
- Methanone, (5-bromo-4-fluoro-2-hydroxyphenyl)(3-hydroxy-2-pyridinyl)-, O-(1,1-dimethylethyl)oxime, (1Z)-162267-73-4C16H16BrFN2O3
- 2-[(2,5-Dimethylphenyl)(nitroso)methylidene]-1,2-dihydropyridine64306-52-1C14H14N2O
- (Z)-N-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl](4-nitrophenyl)methylidene}hydroxylamine339106-02-4C13H7ClF3N3O3
- {6-[(3,4-Difluorophenyl)(hydroxyimino)methyl]pyridin-3-yl}methanol1137950-82-3C13H10F2N2O2
- 6-Chloro-2-[nitroso(phenyl)methylidene]-1,2-dihydropyridin-3-amine50531-93-6C12H10ClN3O
- 6-Chloro-2-[(2-fluorophenyl)(nitroso)methylidene]-1,2-dihydropyridin-3-amine57059-35-5C12H9ClFN3O
- 2-[(E)-[2-Hydroxy-5-(trifluoromethyl)phenyl](methoxyimino)methyl]pyridin-3-ol162267-07-4C14H11F3N2O3
- 2-Pyridyl 4-tolyl ketone hydrazone59742-92-6C13H13N3
- 2-[(4-Trifluoromethylphenyl)(hydrazono)methyl]pyridine1613186-47-2C13H10F3N3
- 2-[(4-Cyanophenyl)(hydrazono)methyl]pyridine57954-98-0C13H10N4
- 2-[(4-Methoxyphenyl)(hydrazono)methyl]pyridine78539-95-4C13H13N3O
- [(5-Bromopyridin-2-yl)phenylmethylene]hydrazone1613186-51-8C12H10BrN3
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(Cc2ccccc2)cc1952 chemicals
c1ccc(Oc2ccccc2)cc1933 chemicals
O=C(c1ccccc1)c1ccccc1537 chemicals
c1ccc(Nc2ccccc2)cc1395 chemicals
c1ccc(CN2CCCCC2)cc1283 chemicals
c1ccc(CN2CCNCC2)cc1267 chemicals
O=S(=O)(c1ccccc1)N1CCCCC1266 chemicals
c1ccc(Oc2ccccn2)cc1238 chemicals
c1ccc(Sc2ccccc2)cc1195 chemicals
O=S(=O)(c1ccccc1)N1CCNCC1195 chemicals
c1ccc(OC2CCCCO2)cc1164 chemicals
O=C(c1ccccc1)N1CCCCC1164 chemicals