Murcko scaffold
Canthin-6-one scaffold
26 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 17
- Chemicals
- 26
- With full pages
- 16
Scaffold SMILES
O=c1ccc2nccc3c4ccccc4n1c23
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 26 of 26 chemicals
Canthin-6-one
CAS 479-43-6C14H8N2O
6H-Indolo(3,2,1-de)(1,5)naphthyridin-6-one, 10-methoxy-
CAS 86293-40-5C15H10N2O2
10-Hydroxycanthin-6-one
CAS 86293-41-6C14H8N2O2
1,11-Dimethoxycanthin-6-one
CAS 103839-24-3C16H12N2O3
![6H-Indolo[3,2,1-de][1,5]naphthyridin-6-one, 4-(methylthio)- chemical structure, C15H10N2OS, CAS 500299-14-9](/s/HCKATCNEEDQXNJ-UHFFFAOYSA-N.svg)
6H-Indolo[3,2,1-de][1,5]naphthyridin-6-one, 4-(methylthio)-
CAS 500299-14-9C15H10N2OS
5-Methoxycanthin-6-one
CAS 15071-56-4C15H10N2O2
![Methyl 6-oxo-6H-indolo[3,2,1-de][1,5]naphthyridine-5-carboxylate chemical structure, C16H10N2O3, CAS 55854-61-0](/s/WNAJYDOQFSRSHC-UHFFFAOYSA-N.svg)
Methyl 6-oxo-6H-indolo[3,2,1-de][1,5]naphthyridine-5-carboxylate
CAS 55854-61-0C16H10N2O3
1-Methoxycanthinone
CAS 60755-86-4C15H10N2O2
4,5-Dimethoxycanthin-6-one
CAS 18110-87-7C16H12N2O3
4-Methoxy-5-hydroxycanthin-6-one
CAS 18110-86-6C15H10N2O3
6H-Indolo(3,2,1-de)(1,5)naphthyridin-6-one, 8-hydroxy-
CAS 66762-19-4C14H8N2O2
9-Methoxy-6H-indolo(3,2,1-de)(1,5)naphthyridin-6-one
CAS 74991-91-6C15H10N2O2
Canthin-6-one N-oxide
CAS 60755-87-5C14H8N2O2
2-Methoxycanthin-6-one
CAS 116353-93-6C15H10N2O2
9,10-Dimethoxycanthin-6-one
CAS 155861-51-1C16H12N2O3
1-Hydroxy-9-medroxycanthin-6-one
CAS 622408-85-9C15H10N2O3
Drymaritin
CAS 5023-08-5C15H10N2O2
![Methyl 6-oxo-6H-indolo[3,2,1-de][1,5]naphthyridine-2-carboxylate chemical structure, C16H10N2O3, CAS 84133-31-3](/s/XQXQAMBHZZKHOL-UHFFFAOYSA-N.svg)
Methyl 6-oxo-6H-indolo[3,2,1-de][1,5]naphthyridine-2-carboxylate
CAS 84133-31-3C16H10N2O3
9-Methoxycanthin-6-one-N-oxide
CAS 137739-74-3C15H10N2O3
Picrasidine Q
CAS 101219-61-8C15H10N2O3
1-Hydroxycanthin-6-one
CAS 80787-59-3C14H8N2O2
4,9-Dimethoxycanthin-6-one
CAS 1270001-72-3C16H12N2O3
Luotonin C
CAS 261948-33-8C16H12N2O2
Luotonin D
CAS 261948-34-9C17H14N2O2
Related scaffolds
Same ring framework with different atoms or bond orders
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c1ccc2c(c1)c1c3n2CCNC3CCC112 chemicals![Scaffold O=c1[nH]nc2c3c(cccc13)-c1ccccc1-2](/scaffold/IKVRZIDOALZALL-UHFFFAOYSA-N/structure.svg)
O=c1[nH]nc2c3c(cccc13)-c1ccccc1-24 chemicals
c1ccc2c(c1)c1c3n2CCNC3=NCC12 chemicals![Scaffold O=c1cc2[nH]ccc3c-2n(c1=O)c1ccccc31](/scaffold/HMEKWKDTZSMLPA-UHFFFAOYSA-N/structure.svg)
O=c1cc2[nH]ccc3c-2n(c1=O)c1ccccc312 chemicals
C1=Cn2c3c(c4ccccc42)CCNC3C12 chemicals
c1ccc2c(c1)c1c3n2CCN=C3CCC12 chemicals
c1ccc2c(c1)-c1cccc3cncc-2c131 chemical![Scaffold O=c1cc2c3ccccc3n3c(=O)ccc([nH]1)c23](/scaffold/BDCOKQCMZJCYDY-UHFFFAOYSA-N/structure.svg)
O=c1cc2c3ccccc3n3c(=O)ccc([nH]1)c231 chemical![Scaffold O=c1cccc2c1c1cc[nH]c3ccc(=O)n2c31](/scaffold/IZNXKZBIIFOWPU-UHFFFAOYSA-N/structure.svg)
O=c1cccc2c1c1cc[nH]c3ccc(=O)n2c311 chemical
c1ccc2c(c1)-c1nccc3ccnc-2c131 chemical
c1ccc2c(c1)c1c3c(nccn32)CCC11 chemical