CompoundList
Sign in
Murcko scaffold

Ring system with 5 rings and 24 atoms

14 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
24
Chemicals
14
With full pages
3
Scaffold SMILES

c1ccc(-c2nnc3sc(C4COc5ccccc5O4)nn23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2nnc3sc(C4COc5ccccc5O4)nn23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

6-(2,3-Dihydro-1,4-benzodioxin-2-yl)-3-(4-methylphenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C18H14N4O2S, CAS 794548-79-1
6-(2,3-Dihydro-1,4-benzodioxin-2-yl)-3-(4-methylphenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 794548-79-1C18H14N4O2S
6-(2,3-Dihydro-1,4-benzodioxin-2-yl)-3-(4-fluorophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C17H11FN4O2S, CAS 791824-33-4
6-(2,3-Dihydro-1,4-benzodioxin-2-yl)-3-(4-fluorophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 791824-33-4C17H11FN4O2S
3-(2-Chlorophenyl)-6-(2,3-dihydro-1,4-benzodioxin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C17H11ClN4O2S, CAS 708286-37-7
3-(2-Chlorophenyl)-6-(2,3-dihydro-1,4-benzodioxin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 708286-37-7C17H11ClN4O2S
3-(3-Chlorophenyl)-6-(2,3-dihydro-1,4-benzodioxin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C17H11ClN4O2S, CAS 791824-43-6
3-(3-Chlorophenyl)-6-(2,3-dihydro-1,4-benzodioxin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 791824-43-6C17H11ClN4O2S
3-(2-Bromophenyl)-6-(2,3-dihydro-1,4-benzodioxin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C17H11BrN4O2S, CAS 825606-62-0
3-(2-Bromophenyl)-6-(2,3-dihydro-1,4-benzodioxin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 825606-62-0C17H11BrN4O2S
6-(2,3-Dihydro-1,4-benzodioxin-3-yl)-3-(2-methoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C18H14N4O3S, CAS 825605-78-5
6-(2,3-Dihydro-1,4-benzodioxin-3-yl)-3-(2-methoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 825605-78-5C18H14N4O3S
6-(2,3-Dihydro-1,4-benzodioxin-2-yl)-3-(3-methylphenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C18H14N4O2S, CAS 882642-43-5
6-(2,3-Dihydro-1,4-benzodioxin-2-yl)-3-(3-methylphenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 882642-43-5C18H14N4O2S
3-(4-Chlorophenyl)-6-(2,3-dihydro-1,4-benzodioxin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C17H11ClN4O2S, CAS 878429-43-7
3-(4-Chlorophenyl)-6-(2,3-dihydro-1,4-benzodioxin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 878429-43-7C17H11ClN4O2S
6-(2,3-Dihydro-1,4-benzodioxin-3-yl)-3-(4-methoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C18H14N4O3S, CAS 878429-82-4
6-(2,3-Dihydro-1,4-benzodioxin-3-yl)-3-(4-methoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 878429-82-4C18H14N4O3S
6-(2,3-Dihydro-1,4-benzodioxin-2-yl)-3-(3,4-dimethoxyphenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C19H16N4O4S, CAS 878430-79-6
6-(2,3-Dihydro-1,4-benzodioxin-2-yl)-3-(3,4-dimethoxyphenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 878430-79-6C19H16N4O4S
4-[6-(2,3-Dihydro-1,4-benzodioxin-3-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl]-N,N-dimethylaniline chemical structure, C19H17N5O2S, CAS 878431-38-0
4-[6-(2,3-Dihydro-1,4-benzodioxin-3-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl]-N,N-dimethylaniline
CAS 878431-38-0C19H17N5O2S
6-(2,3-Dihydro-1,4-benzodioxin-2-yl)-3-(3-fluorophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C17H11FN4O2S, CAS 724435-92-1
6-(2,3-Dihydro-1,4-benzodioxin-2-yl)-3-(3-fluorophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 724435-92-1C17H11FN4O2S
3-[6-(2,3-Dihydro-1,4-benzodioxin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl]phenyl methyl ether chemical structure, C18H14N4O3S, CAS 947949-79-3
3-[6-(2,3-Dihydro-1,4-benzodioxin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl]phenyl methyl ether
CAS 947949-79-3C18H14N4O3S
3-(3-Bromophenyl)-6-(2,3-dihydro-1,4-benzodioxin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C17H11BrN4O2S, CAS 1082767-51-8
3-(3-Bromophenyl)-6-(2,3-dihydro-1,4-benzodioxin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 1082767-51-8C17H11BrN4O2S