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Murcko scaffold

RefChem:345356 scaffold

5 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
5
With full pages
3
Scaffold SMILES

O=C(Nc1cccc(-c2nc3ccccc3s2)c1)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the RefChem:345356 page
Murcko scaffold O=C(Nc1cccc(-c2nc3ccccc3s2)c1)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

N-[3-(1,3-Benzothiazol-2-yl)-2-methylphenyl]thiophene-2-carboxamide chemical structure, C19H14N2OS2, CAS 428447-87-4
N-[3-(1,3-Benzothiazol-2-yl)-2-methylphenyl]thiophene-2-carboxamide
CAS 428447-87-4C19H14N2OS2
RefChem:345356 chemical structure, C18H12N2OS2, CAS 6014-37-5
RefChem:345356
CAS 6014-37-5C18H12N2OS2
N-(3-(Benzo[d]thiazol-2-yl)-4-hydroxyphenyl)-5-nitrothiophene-2-carboxamide chemical structure, C18H11N3O4S2, CAS 328038-31-9
N-(3-(Benzo[d]thiazol-2-yl)-4-hydroxyphenyl)-5-nitrothiophene-2-carboxamide
CAS 328038-31-9C18H11N3O4S2
N-(3-(Benzo[d]thiazol-2-yl)-4-hydroxyphenyl)-5-bromothiophene-2-carboxamide chemical structure, C18H11BrN2O2S2, CAS 391223-77-1
N-(3-(Benzo[d]thiazol-2-yl)-4-hydroxyphenyl)-5-bromothiophene-2-carboxamide
CAS 391223-77-1C18H11BrN2O2S2
N-(3-(Benzo[d]thiazol-2-yl)-4-hydroxyphenyl)thiophene-2-carboxamide chemical structure, C18H12N2O2S2, CAS 312748-42-8
N-(3-(Benzo[d]thiazol-2-yl)-4-hydroxyphenyl)thiophene-2-carboxamide
CAS 312748-42-8C18H12N2O2S2