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Murcko scaffold

Ring system with 4 rings and 22 atoms

7 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
7
With full pages
2
Scaffold SMILES

O=C(Nc1ccc2[nH]c3c(c2c1)CCCC3)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc2[nH]c3c(c2c1)CCCC3)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

4-Fluoro-N-(2,3,4,9-tetrahydro-1H-carbazol-6-yl)benzamide chemical structure, C19H17FN2O, CAS 622793-13-9
4-Fluoro-N-(2,3,4,9-tetrahydro-1H-carbazol-6-yl)benzamide
CAS 622793-13-9C19H17FN2O
3,4-Dimethoxy-N-(2,3,4,9-tetrahydro-1H-carbazol-6-yl)benzamide chemical structure, C21H22N2O3, CAS 622793-27-5
3,4-Dimethoxy-N-(2,3,4,9-tetrahydro-1H-carbazol-6-yl)benzamide
CAS 622793-27-5C21H22N2O3
LY-344864 chemical structure, C21H22FN3O, CAS 186544-26-3
LY-344864
CAS 186544-26-3C21H22FN3O
LY 344864 racemate chemical structure, C21H22FN3O, CAS 186543-64-6
LY 344864 racemate
CAS 186543-64-6C21H22FN3O
6-(Benzoyl)amino-3-(dimethyl)amino-1,2,3,4-tetrahydro-9H-carbazole chemical structure, C21H23N3O, CAS 186543-66-8
6-(Benzoyl)amino-3-(dimethyl)amino-1,2,3,4-tetrahydro-9H-carbazole
CAS 186543-66-8C21H23N3O
(R)-N-(3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl)-4-fluorobenzamide hydrochloride chemical structure, C21H23ClFN3O, CAS 1217756-94-9
(R)-N-(3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl)-4-fluorobenzamide hydrochloride
CAS 1217756-94-9C21H23ClFN3O
LY 344864 S-enantiomer chemical structure, C21H22FN3O, CAS 186544-27-4
LY 344864 S-enantiomer
CAS 186544-27-4C21H22FN3O