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Murcko scaffold

3H-Imidazo[4,5-c]pyridin-2-ol scaffold

68 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
68
With full pages
11
Scaffold SMILES

O=c1[nH]c2ccncc2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3H-Imidazo[4,5-c]pyridin-2-ol page
Murcko scaffold O=c1[nH]c2ccncc2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 68 of 68 chemicals

7-Methyl-1-(2,2,2-trifluoroethyl)-3H-imidazo[4,5-c]pyridin-2-one chemical structure, C9H8F3N3O, CAS 1513846-85-9
7-Methyl-1-(2,2,2-trifluoroethyl)-3H-imidazo[4,5-c]pyridin-2-one
CAS 1513846-85-9C9H8F3N3O
4-Bromo-1H,2H,3H-imidazo(4,5-c)pyridin-2-one chemical structure, C6H4BrN3O, CAS 54221-74-8
4-Bromo-1H,2H,3H-imidazo(4,5-c)pyridin-2-one
CAS 54221-74-8C6H4BrN3O
6-Methyl-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one chemical structure, C7H7N3O, CAS 2384650-83-1
6-Methyl-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one
CAS 2384650-83-1C7H7N3O
4,6-Difluoro-1H-imidazo[4,5-c]pyridin-2(3H)-one chemical structure, C6H3F2N3O, CAS 2386121-16-8
4,6-Difluoro-1H-imidazo[4,5-c]pyridin-2(3H)-one
CAS 2386121-16-8C6H3F2N3O
2-(1-Methyl-2-oxoimidazo[4,5-c]pyridin-3-yl)ethanesulfonyl fluoride chemical structure, C9H10FN3O3S, CAS 2249670-28-6
2-(1-Methyl-2-oxoimidazo[4,5-c]pyridin-3-yl)ethanesulfonyl fluoride
CAS 2249670-28-6C9H10FN3O3S
Methyl 2-hydroxy-1H-imidazo[4,5-c]pyridine-7-carboxylate chemical structure, C8H7N3O3, CAS 2112668-59-2
Methyl 2-hydroxy-1H-imidazo[4,5-c]pyridine-7-carboxylate
CAS 2112668-59-2C8H7N3O3
6-(Trifluoromethyl)-3H-imidazo[4,5-c]pyridin-2-ol chemical structure, C7H4F3N3O, CAS 2385582-11-4
6-(Trifluoromethyl)-3H-imidazo[4,5-c]pyridin-2-ol
CAS 2385582-11-4C7H4F3N3O
6-Bromo-1H-imidazo[4,5-c]pyridin-2(3H)-one chemical structure, C6H4BrN3O, CAS 1446413-78-0
6-Bromo-1H-imidazo[4,5-c]pyridin-2(3H)-one
CAS 1446413-78-0C6H4BrN3O
6-Bromo-1-ethyl-3H-imidazo[4,5-c]pyridin-2-one chemical structure, C8H8BrN3O, CAS 2734094-64-3
6-Bromo-1-ethyl-3H-imidazo[4,5-c]pyridin-2-one
CAS 2734094-64-3C8H8BrN3O
6-Bromo-1-methyl-1H-imidazo[4,5-c]pyridin-2(3H)-one chemical structure, C7H6BrN3O, CAS 2167569-96-0
6-Bromo-1-methyl-1H-imidazo[4,5-c]pyridin-2(3H)-one
CAS 2167569-96-0C7H6BrN3O
4,6-Dichloro-1-methyl-3H-imidazo[4,5-c]pyridin-2-one chemical structure, C7H5Cl2N3O, CAS 2769718-07-0
4,6-Dichloro-1-methyl-3H-imidazo[4,5-c]pyridin-2-one
CAS 2769718-07-0C7H5Cl2N3O
4,6-Dichloro-1,3-dimethyl-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one chemical structure, C8H7Cl2N3O, CAS 2769718-08-1
4,6-Dichloro-1,3-dimethyl-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one
CAS 2769718-08-1C8H7Cl2N3O
4-Amino-2-hydroxy-1H-imidazo[4,5-c]pyridine-7-carboxylic acid chemical structure, C7H6N4O3, CAS 2920131-17-3
4-Amino-2-hydroxy-1H-imidazo[4,5-c]pyridine-7-carboxylic acid
CAS 2920131-17-3C7H6N4O3
4-Amino-7-bromo-1H,2H,3H-imidazo[4,5-c]pyridin-2-one chemical structure, C6H5BrN4O, CAS 2920135-92-6
4-Amino-7-bromo-1H,2H,3H-imidazo[4,5-c]pyridin-2-one
CAS 2920135-92-6C6H5BrN4O
2-Oxo-1H,2H,3H-imidazo[4,5-c]pyridine-4-carboxylic acid chemical structure, C7H5N3O3, CAS 2920158-49-0
2-Oxo-1H,2H,3H-imidazo[4,5-c]pyridine-4-carboxylic acid
CAS 2920158-49-0C7H5N3O3
4-Amino-7-iodo-1H-imidazo[4,5-c]pyridin-2-ol chemical structure, C6H5IN4O, CAS 2920118-20-1
4-Amino-7-iodo-1H-imidazo[4,5-c]pyridin-2-ol
CAS 2920118-20-1C6H5IN4O
Ethyl 2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridine-7-carboxylate chemical structure, C9H9N3O3, CAS 1266114-40-2
Ethyl 2-oxo-2,3-dihydro-1H-imidazo[4,5-c]pyridine-7-carboxylate
CAS 1266114-40-2C9H9N3O3
6-Chloro-1,3-dimethyl-1,3-dihydro-2H-imidazo[4,5-C]pyridin-2-one chemical structure, C8H8ClN3O, CAS 331275-89-9
6-Chloro-1,3-dimethyl-1,3-dihydro-2H-imidazo[4,5-C]pyridin-2-one
CAS 331275-89-9C8H8ClN3O
Methyl 2-Hydroxy-3H-imidazo[4,5-c]pyridine-6-carboxylate chemical structure, C8H7N3O3, CAS 2112653-12-8
Methyl 2-Hydroxy-3H-imidazo[4,5-c]pyridine-6-carboxylate
CAS 2112653-12-8C8H7N3O3
4-Methoxy-1H-imidazo[4,5-c]pyridin-2-ol chemical structure, C7H7N3O2, CAS 2504078-18-4
4-Methoxy-1H-imidazo[4,5-c]pyridin-2-ol
CAS 2504078-18-4C7H7N3O2