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Murcko scaffold

2-Phenyl-1,3-thiazolidin-4-one scaffold

45 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
45
With full pages
13
Scaffold SMILES

O=C1CSC(c2ccccc2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenyl-1,3-thiazolidin-4-one page
Murcko scaffold O=C1CSC(c2ccccc2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 45 of 45 chemicals

2-Phenyl-3-(N,N-dimethylaminopropyl)-1,3-thiazolidin-4-one chemical structure, C14H21ClN2OS, CAS 141955-94-4
2-Phenyl-3-(N,N-dimethylaminopropyl)-1,3-thiazolidin-4-one
CAS 141955-94-4C14H21ClN2OS
KM 1146 chemical structure, C12H15NO3S, CAS 82697-73-2
KM 1146
CAS 82697-73-2C12H15NO3S
4-Thiazolidinone, 3-hydroxy-2-phenyl- chemical structure, C9H9NO2S, CAS 65655-88-1
4-Thiazolidinone, 3-hydroxy-2-phenyl-
CAS 65655-88-1C9H9NO2S
2-Phenyl-1,3-thiazolidin-4-one chemical structure, C9H9NOS, CAS 10220-27-6
2-Phenyl-1,3-thiazolidin-4-one
CAS 10220-27-6C9H9NOS
2-(4-Bromophenyl)-2-methyl-1,3-thiazolidin-4-one chemical structure, C10H10BrNOS, CAS 309294-12-0
2-(4-Bromophenyl)-2-methyl-1,3-thiazolidin-4-one
CAS 309294-12-0C10H10BrNOS
2-(2-Fluorophenyl)-1,3-thiazolan-4-one chemical structure, C9H8FNOS, CAS 883014-09-3
2-(2-Fluorophenyl)-1,3-thiazolan-4-one
CAS 883014-09-3C9H8FNOS
2-(4-Chlorophenyl)-5-methyl-1,3-thiazolidin-4-one chemical structure, C10H10ClNOS, CAS 293324-84-2
2-(4-Chlorophenyl)-5-methyl-1,3-thiazolidin-4-one
CAS 293324-84-2C10H10ClNOS
2-(3,4,5-Trimethoxyphenyl)-1,3-thiazolidin-4-one chemical structure, C12H15NO4S, CAS 77381-90-9
2-(3,4,5-Trimethoxyphenyl)-1,3-thiazolidin-4-one
CAS 77381-90-9C12H15NO4S
2-(4-Methoxyphenyl)-5-methyl-2,5-dihydro-1,3-thiazol-4-ol chemical structure, C11H13NO2S, CAS 82697-75-4
2-(4-Methoxyphenyl)-5-methyl-2,5-dihydro-1,3-thiazol-4-ol
CAS 82697-75-4C11H13NO2S
2-(4-Chlorophenyl)-1,3-thiazolidin-4-one chemical structure, C9H8ClNOS, CAS 114371-93-6
2-(4-Chlorophenyl)-1,3-thiazolidin-4-one
CAS 114371-93-6C9H8ClNOS
2-(3,4-Dimethoxyphenyl)-3-[3-(dimethylamino)propyl]-1,3-thiazolidin-4-one chemical structure, C16H24N2O3S, CAS 312632-20-5
2-(3,4-Dimethoxyphenyl)-3-[3-(dimethylamino)propyl]-1,3-thiazolidin-4-one
CAS 312632-20-5C16H24N2O3S
3-[3-(Dimethylamino)propyl]-2-(4-nitrophenyl)-1,3-thiazolidin-4-one chemical structure, C14H19N3O3S, CAS 141956-17-4
3-[3-(Dimethylamino)propyl]-2-(4-nitrophenyl)-1,3-thiazolidin-4-one
CAS 141956-17-4C14H19N3O3S
2-(4-Chlorophenyl)-3-[3-(dimethylamino)propyl]-1,3-thiazolidin-4-one chemical structure, C14H19ClN2OS, CAS 141956-13-0
2-(4-Chlorophenyl)-3-[3-(dimethylamino)propyl]-1,3-thiazolidin-4-one
CAS 141956-13-0C14H19ClN2OS
3-(3-Dimethylaminopropyl)-2-(3-nitrophenyl)thiazolidin-4-one hydrochloride chemical structure, C14H20ClN3O3S, CAS 5682-67-7
3-(3-Dimethylaminopropyl)-2-(3-nitrophenyl)thiazolidin-4-one hydrochloride
CAS 5682-67-7C14H20ClN3O3S
3-[3-(Dimethylamino)propyl]-2-(3-nitrophenyl)-1,3-thiazolidin-4-one chemical structure, C14H19N3O3S, CAS 141956-25-4
3-[3-(Dimethylamino)propyl]-2-(3-nitrophenyl)-1,3-thiazolidin-4-one
CAS 141956-25-4C14H19N3O3S
2-(2,6-Dichlorophenyl)-3-[3-(dimethylamino)propyl]-5-methyl-1,3-thiazolidin-4-one hydrochloride chemical structure, C15H21Cl3N2OS, CAS 5836-86-2
2-(2,6-Dichlorophenyl)-3-[3-(dimethylamino)propyl]-5-methyl-1,3-thiazolidin-4-one hydrochloride
CAS 5836-86-2C15H21Cl3N2OS
2-(3,4-Dimethoxyphenyl)-1,3-thiazolidin-4-one chemical structure, C11H13NO3S, CAS 77386-55-1
2-(3,4-Dimethoxyphenyl)-1,3-thiazolidin-4-one
CAS 77386-55-1C11H13NO3S
3-Butyl-2-(2-hydroxy-5-methylphenyl)-2-methyl-1,3-thiazolidin-4-one chemical structure, C15H21NO2S, CAS 60121-34-8
3-Butyl-2-(2-hydroxy-5-methylphenyl)-2-methyl-1,3-thiazolidin-4-one
CAS 60121-34-8C15H21NO2S
2-(2-Methoxyphenyl)-5-methyl-2,5-dihydro-1,3-thiazol-4-ol chemical structure, C11H13NO2S, CAS 82697-74-3
2-(2-Methoxyphenyl)-5-methyl-2,5-dihydro-1,3-thiazol-4-ol
CAS 82697-74-3C11H13NO2S
N-(4-Oxo-2-phenyl-1,3-thiazolidin-3-yl)carbamimidothioic acid chemical structure, C10H11N3OS2, CAS 130111-89-6
N-(4-Oxo-2-phenyl-1,3-thiazolidin-3-yl)carbamimidothioic acid
CAS 130111-89-6C10H11N3OS2
Thiourea, (2-(4-methoxyphenyl)-4-oxo-3-thiazolidinyl)- chemical structure, C11H13N3O2S2, CAS 130111-91-0
Thiourea, (2-(4-methoxyphenyl)-4-oxo-3-thiazolidinyl)-
CAS 130111-91-0C11H13N3O2S2
Methyl 4-(4-oxo-1,3-thiazolidin-2-yl)benzoate chemical structure, C11H11NO3S, CAS 332026-49-0
Methyl 4-(4-oxo-1,3-thiazolidin-2-yl)benzoate
CAS 332026-49-0C11H11NO3S
4-Thiazolidinone, 3-butyl-2-phenyl- chemical structure, C13H17NOS, CAS 65655-82-5
4-Thiazolidinone, 3-butyl-2-phenyl-
CAS 65655-82-5C13H17NOS
3-(2-Hydroxypropyl)-2-[3-(trifluoromethyl)phenyl]-1,3-thiazolan-4-one chemical structure, C13H14F3NO2S, CAS 866042-09-3
3-(2-Hydroxypropyl)-2-[3-(trifluoromethyl)phenyl]-1,3-thiazolan-4-one
CAS 866042-09-3C13H14F3NO2S