Murcko scaffold
2,3,4,7,8,9-Hexahydrooxecin-10-one scaffold
10 chemicals on CompoundList share this ring system.
- Rings
- 1
- Scaffold atoms
- 11
- Chemicals
- 10
- With full pages
- 5
Scaffold SMILES
O=C1CCCC=CCCCO1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 10 of 10 chemicals
10-Methyl-3,4,5,8,9,10-hexahydro-2H-oxecin-2-one
CAS 136230-43-8C10H16O2
Herbarumin iii
CAS 533935-64-7C12H20O3
Pinolidoxin
CAS 152985-39-2C18H26O6
Decarestrictine N
CAS 147705-04-2C10H16O5
Decarestrictine D
CAS 127393-89-9C10H16O5
Herbarumin ii
CAS 297174-26-6C12H20O5
Stagonolide B
CAS 1004760-95-5C12H20O5
Stagonolide C
CAS 1004760-96-6C10H16O4
2,3,4,7,8,9-Hexahydrooxecin-10-one
CAS 110189-65-6C9H14O2
Herbarumin I
CAS 297174-24-4C12H20O4
Related scaffolds
Same ring framework with different atoms or bond orders
C=C1C=CCCCC=CCC13 chemicals
C1CCCCCCCCC13 chemicals
C1=CCCCCCCCC13 chemicals
O=C1CCCCC=CCCO13 chemicals![Scaffold O1[SiH2]O[SiH2]O[SiH2]O[SiH2]O[SiH2]1](/scaffold/CCPYCNSBZPTUMJ-UHFFFAOYSA-N/structure.svg)
O1[SiH2]O[SiH2]O[SiH2]O[SiH2]O[SiH2]12 chemicals
O=C1CCCCCCCCO12 chemicals
O=C1C=CCC=CCCCO12 chemicals
C1=CCCCCC=CCC12 chemicals
O=C1CCCCCCCCC12 chemicals
C=C1CC=CCCC=CCC1=O2 chemicals
O=C1CCNCCCCCN12 chemicals
C1#CCCCCCCCC11 chemical