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Murcko scaffold

4-(1,3,4-Thiadiazol-2-yl)piperidine scaffold

38 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
38
With full pages
3
Scaffold SMILES

c1nnc(C2CCNCC2)s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(1,3,4-Thiadiazol-2-yl)piperidine page
Murcko scaffold c1nnc(C2CCNCC2)s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 38 of 38 chemicals

5-(Piperidin-4-yl)-1,3,4-thiadiazol-2-amine chemical structure, C7H12N4S, CAS 881040-24-0
5-(Piperidin-4-yl)-1,3,4-thiadiazol-2-amine
CAS 881040-24-0C7H12N4S
5-{1-[(tert-Butoxy)carbonyl]piperidin-4-yl}-1,3,4-thiadiazole-2-carboxylic acid chemical structure, C13H19N3O4S, CAS 189695-65-6
5-{1-[(tert-Butoxy)carbonyl]piperidin-4-yl}-1,3,4-thiadiazole-2-carboxylic acid
CAS 189695-65-6C13H19N3O4S
1-(4-(5-Ethyl-1,3,4-thiadiazol-2-yl)piperidin-1-yl)-3,3-dimethylbutan-1-one chemical structure, C15H25N3OS, CAS 1105203-34-6
1-(4-(5-Ethyl-1,3,4-thiadiazol-2-yl)piperidin-1-yl)-3,3-dimethylbutan-1-one
CAS 1105203-34-6C15H25N3OS
1-(4-(5-Ethyl-1,3,4-thiadiazol-2-yl)piperidin-1-yl)-2,2-dimethylpropan-1-one chemical structure, C14H23N3OS, CAS 1105230-27-0
1-(4-(5-Ethyl-1,3,4-thiadiazol-2-yl)piperidin-1-yl)-2,2-dimethylpropan-1-one
CAS 1105230-27-0C14H23N3OS
Ethyl 4-[4-(5-ethyl-1,3,4-thiadiazol-2-yl)piperidin-1-yl]-4-oxobutanoate chemical structure, C15H23N3O3S, CAS 1105230-43-0
Ethyl 4-[4-(5-ethyl-1,3,4-thiadiazol-2-yl)piperidin-1-yl]-4-oxobutanoate
CAS 1105230-43-0C15H23N3O3S
N-(tert-Butyl)-4-(5-ethyl-1,3,4-thiadiazol-2-yl)piperidine-1-carboxamide chemical structure, C14H24N4OS, CAS 1105209-53-7
N-(tert-Butyl)-4-(5-ethyl-1,3,4-thiadiazol-2-yl)piperidine-1-carboxamide
CAS 1105209-53-7C14H24N4OS
4-(5-Methyl-1,3,4-thiadiazol-2-yl)piperidine chemical structure, C8H13N3S, CAS 933728-47-3
4-(5-Methyl-1,3,4-thiadiazol-2-yl)piperidine
CAS 933728-47-3C8H13N3S
Ethyl 2-(4-(5-ethyl-1,3,4-thiadiazol-2-yl)piperidin-1-yl)-2-oxoacetate chemical structure, C13H19N3O3S, CAS 1170147-47-3
Ethyl 2-(4-(5-ethyl-1,3,4-thiadiazol-2-yl)piperidin-1-yl)-2-oxoacetate
CAS 1170147-47-3C13H19N3O3S
2-(1-(Butylsulfonyl)piperidin-4-yl)-5-ethyl-1,3,4-thiadiazole chemical structure, C13H23N3O2S2, CAS 1171373-92-4
2-(1-(Butylsulfonyl)piperidin-4-yl)-5-ethyl-1,3,4-thiadiazole
CAS 1171373-92-4C13H23N3O2S2
2-Ethyl-5-(1-(propylsulfonyl)piperidin-4-yl)-1,3,4-thiadiazole chemical structure, C12H21N3O2S2, CAS 1171192-85-0
2-Ethyl-5-(1-(propylsulfonyl)piperidin-4-yl)-1,3,4-thiadiazole
CAS 1171192-85-0C12H21N3O2S2
4-(5-Ethyl-1,3,4-thiadiazol-2-yl)-N-isopropylpiperidine-1-carboxamide chemical structure, C13H22N4OS, CAS 1170804-13-3
4-(5-Ethyl-1,3,4-thiadiazol-2-yl)-N-isopropylpiperidine-1-carboxamide
CAS 1170804-13-3C13H22N4OS
4-(1,3,4-Thiadiazol-2-yl)piperidine chemical structure, C7H11N3S, CAS 933755-69-2
4-(1,3,4-Thiadiazol-2-yl)piperidine
CAS 933755-69-2C7H11N3S
N-[5-(Piperidin-4-yl)-1,3,4-thiadiazol-2-yl]propanamide chemical structure, C10H16N4OS, CAS 1282351-70-5
N-[5-(Piperidin-4-yl)-1,3,4-thiadiazol-2-yl]propanamide
CAS 1282351-70-5C10H16N4OS
N-[5-(Piperidin-4-yl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C9H14N4OS, CAS 1267477-40-6
N-[5-(Piperidin-4-yl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 1267477-40-6C9H14N4OS
N-[5-(Piperidin-4-yl)-1,3,4-thiadiazol-2-yl]methanesulfonamide chemical structure, C8H14N4O2S2, CAS 1267152-54-4
N-[5-(Piperidin-4-yl)-1,3,4-thiadiazol-2-yl]methanesulfonamide
CAS 1267152-54-4C8H14N4O2S2
5-(Piperidin-4-yl)-1,3,4-thiadiazole-2-carboxylic acid chemical structure, C8H11N3O2S, CAS 933731-09-0
5-(Piperidin-4-yl)-1,3,4-thiadiazole-2-carboxylic acid
CAS 933731-09-0C8H11N3O2S
Methyl 5-(piperidin-4-yl)-1,3,4-thiadiazole-2-carboxylate chemical structure, C9H13N3O2S, CAS 1784104-17-1
Methyl 5-(piperidin-4-yl)-1,3,4-thiadiazole-2-carboxylate
CAS 1784104-17-1C9H13N3O2S
2-Bromo-5-(4-piperidyl)-1,3,4-thiadiazole chemical structure, C7H10BrN3S, CAS 1784368-89-3
2-Bromo-5-(4-piperidyl)-1,3,4-thiadiazole
CAS 1784368-89-3C7H10BrN3S
[5-(Piperidin-4-yl)-1,3,4-thiadiazol-2-yl]methanamine chemical structure, C8H14N4S, CAS 933723-76-3
[5-(Piperidin-4-yl)-1,3,4-thiadiazol-2-yl]methanamine
CAS 933723-76-3C8H14N4S
4-(5-Methyl-1,3,4-thiadiazol-2-yl)piperidine hydrochloride chemical structure, C8H14ClN3S, CAS 2155853-01-1
4-(5-Methyl-1,3,4-thiadiazol-2-yl)piperidine hydrochloride
CAS 2155853-01-1C8H14ClN3S
tert-Butyl 4-[5-(chloromethyl)-1,3,4-thiadiazol-2-yl]piperidine-1-carboxylate chemical structure, C13H20ClN3O2S, CAS 2411230-41-4
tert-Butyl 4-[5-(chloromethyl)-1,3,4-thiadiazol-2-yl]piperidine-1-carboxylate
CAS 2411230-41-4C13H20ClN3O2S
tert-Butyl 4-[5-(aminomethyl)-1,3,4-thiadiazol-2-yl]piperidine-1-carboxylate chemical structure, C13H22N4O2S, CAS 2411286-42-3
tert-Butyl 4-[5-(aminomethyl)-1,3,4-thiadiazol-2-yl]piperidine-1-carboxylate
CAS 2411286-42-3C13H22N4O2S
Ethyl 5-(piperidin-4-yl)-1,3,4-thiadiazole-2-carboxylate hydrochloride chemical structure, C10H16ClN3O2S, CAS 2411275-39-1
Ethyl 5-(piperidin-4-yl)-1,3,4-thiadiazole-2-carboxylate hydrochloride
CAS 2411275-39-1C10H16ClN3O2S
Ethyl 5-(piperidin-4-yl)-1,3,4-thiadiazole-2-carboxylate chemical structure, C10H15N3O2S, CAS 2105612-66-4
Ethyl 5-(piperidin-4-yl)-1,3,4-thiadiazole-2-carboxylate
CAS 2105612-66-4C10H15N3O2S