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Murcko scaffold

1-Oxa-6-azaspiro[3.3]heptane scaffold

27 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
7
Chemicals
27
With full pages
4
Scaffold SMILES

C1CC2(CNC2)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Oxa-6-azaspiro[3.3]heptane page
Murcko scaffold C1CC2(CNC2)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

tert-Butyl 1-oxa-6-azaspiro[3.3]heptane-6-carboxylate chemical structure, C10H17NO3, CAS 1223573-41-8
tert-Butyl 1-oxa-6-azaspiro[3.3]heptane-6-carboxylate
CAS 1223573-41-8C10H17NO3
tert-Butyl 3,3-dimethyl-1-oxa-6-azaspiro[3.3]heptane-6-carboxylate chemical structure, C12H21NO3, CAS 936850-12-3
tert-Butyl 3,3-dimethyl-1-oxa-6-azaspiro[3.3]heptane-6-carboxylate
CAS 936850-12-3C12H21NO3
3,3-Dimethyl-1-oxa-6-azaspiro[3.3]heptane chemical structure, C7H13NO, CAS 1073234-27-1
3,3-Dimethyl-1-oxa-6-azaspiro[3.3]heptane
CAS 1073234-27-1C7H13NO
3,3-Dimethyl-1-oxa-6-azaspiro[3.3]heptane 2,2,2-trifluoroacetate chemical structure, C9H14F3NO3, CAS 1254036-08-2
3,3-Dimethyl-1-oxa-6-azaspiro[3.3]heptane 2,2,2-trifluoroacetate
CAS 1254036-08-2C9H14F3NO3
1-Oxa-6-azaspiro[3.3]heptane chemical structure, C5H9NO, CAS 936947-34-1
1-Oxa-6-azaspiro[3.3]heptane
CAS 936947-34-1C5H9NO
6-Boc-1-oxa-6-azaspiro[3.3]heptan-3-amine chemical structure, C10H18N2O3, CAS 1349199-65-0
6-Boc-1-oxa-6-azaspiro[3.3]heptan-3-amine
CAS 1349199-65-0C10H18N2O3
1-Oxa-6-azaspiro[3.3]heptane-6-carboxylic acid, 3-hydroxy-, 1,1-dimethylethyl ester chemical structure, C10H17NO4, CAS 1349199-63-8
1-Oxa-6-azaspiro[3.3]heptane-6-carboxylic acid, 3-hydroxy-, 1,1-dimethylethyl ester
CAS 1349199-63-8C10H17NO4
1-Oxa-6-azaspiro[3.3]heptane oxalate chemical structure, C7H11NO5, CAS 1427358-60-8
1-Oxa-6-azaspiro[3.3]heptane oxalate
CAS 1427358-60-8C7H11NO5
1-Oxa-6-azaspiro[3.3]heptane trifluoroacetate chemical structure, C7H10F3NO3, CAS 1303587-87-2
1-Oxa-6-azaspiro[3.3]heptane trifluoroacetate
CAS 1303587-87-2C7H10F3NO3
1-Oxa-6-azaspiro(3.3)heptane hydrochloride chemical structure, C5H10ClNO, CAS 1359704-67-8
1-Oxa-6-azaspiro(3.3)heptane hydrochloride
CAS 1359704-67-8C5H10ClNO
1-Oxa-6-azaspiro[3.3]heptane hemioxalate chemical structure, C12H20N2O6, CAS 1523606-38-3
1-Oxa-6-azaspiro[3.3]heptane hemioxalate
CAS 1523606-38-3C12H20N2O6
tert-Butyl (3R)-3-amino-1-oxa-6-azaspiro[3.3]heptane-6-carboxylate chemical structure, C10H18N2O3, CAS 2198241-86-8
tert-Butyl (3R)-3-amino-1-oxa-6-azaspiro[3.3]heptane-6-carboxylate
CAS 2198241-86-8C10H18N2O3
tert-Butyl (S)-3-amino-1-oxa-6-azaspiro[3.3]heptane-6-carboxylate chemical structure, C10H18N2O3, CAS 2306245-34-9
tert-Butyl (S)-3-amino-1-oxa-6-azaspiro[3.3]heptane-6-carboxylate
CAS 2306245-34-9C10H18N2O3
tert-Butyl (3R)-3-hydroxy-1-oxa-6-azaspiro[3.3]heptane-6-carboxylate chemical structure, C10H17NO4, CAS 2199214-82-7
tert-Butyl (3R)-3-hydroxy-1-oxa-6-azaspiro[3.3]heptane-6-carboxylate
CAS 2199214-82-7C10H17NO4
tert-Butyl (3S)-3-hydroxy-1-oxa-6-azaspiro[3.3]heptane-6-carboxylate chemical structure, C10H17NO4, CAS 2306252-24-2
tert-Butyl (3S)-3-hydroxy-1-oxa-6-azaspiro[3.3]heptane-6-carboxylate
CAS 2306252-24-2C10H17NO4
3,3-Dimethyl-1-oxa-6-azaspiro[3.3]heptane hydrochloride chemical structure, C7H14ClNO, CAS 1415562-41-2
3,3-Dimethyl-1-oxa-6-azaspiro[3.3]heptane hydrochloride
CAS 1415562-41-2C7H14ClNO
1-{1-Oxa-6-azaspiro[3.3]heptan-6-yl}ethan-1-one chemical structure, C7H11NO2, CAS 1849308-37-7
1-{1-Oxa-6-azaspiro[3.3]heptan-6-yl}ethan-1-one
CAS 1849308-37-7C7H11NO2
2,2,2-Trifluoro-1-{1-oxa-6-azaspiro[3.3]heptan-6-yl}ethan-1-one chemical structure, C7H8F3NO2, CAS 1878815-34-9
2,2,2-Trifluoro-1-{1-oxa-6-azaspiro[3.3]heptan-6-yl}ethan-1-one
CAS 1878815-34-9C7H8F3NO2
2-(6-(tert-Butoxycarbonyl)-1-oxa-6-azaspiro[3.3]heptan-3-yl)acetic acid chemical structure, C12H19NO5, CAS 1823272-06-5
2-(6-(tert-Butoxycarbonyl)-1-oxa-6-azaspiro[3.3]heptan-3-yl)acetic acid
CAS 1823272-06-5C12H19NO5
tert-Butyl 3-amino-1-oxa-6-azaspiro[3.3]heptane-6-carboxylate hemioxalate chemical structure, C22H38N4O10, CAS 2173992-31-7
tert-Butyl 3-amino-1-oxa-6-azaspiro[3.3]heptane-6-carboxylate hemioxalate
CAS 2173992-31-7C22H38N4O10
3-Fluoro-1-oxa-6-azaspiro[3.3]heptane chemical structure, C5H8FNO, CAS 2925075-08-5
3-Fluoro-1-oxa-6-azaspiro[3.3]heptane
CAS 2925075-08-5C5H8FNO
tert-Butyl (R)-3-amino-1-oxa-6-azaspiro[3.3]heptane-6-carboxylate hydrochloride chemical structure, C10H19ClN2O3, CAS 2920232-53-5
tert-Butyl (R)-3-amino-1-oxa-6-azaspiro[3.3]heptane-6-carboxylate hydrochloride
CAS 2920232-53-5C10H19ClN2O3
3,3-Difluoro-1-oxa-6-azaspiro[3.3]heptane, trifluoroacetic acid chemical structure, C7H8F5NO3, CAS 2639437-17-3
3,3-Difluoro-1-oxa-6-azaspiro[3.3]heptane, trifluoroacetic acid
CAS 2639437-17-3C7H8F5NO3
3,3-Difluoro-1-oxa-6-azaspiro[3.3]heptane chemical structure, C5H7F2NO, CAS 2639412-14-7
3,3-Difluoro-1-oxa-6-azaspiro[3.3]heptane
CAS 2639412-14-7C5H7F2NO