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Murcko scaffold

Ring system with 4 rings and 24 atoms

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
8
With full pages
2
Scaffold SMILES

O=C(Nc1ccccc1N1CCNCC1)c1cc2ccccc2s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1N1CCNCC1)c1cc2ccccc2s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

3-Chloro-N-[2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]-1-benzothiophene-2-carboxamide chemical structure, C23H24ClN3O2S, CAS 695220-79-2
3-Chloro-N-[2-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]-1-benzothiophene-2-carboxamide
CAS 695220-79-2C23H24ClN3O2S
3-Chloro-N-{2-[4-(methylsulfonyl)-1-piperazinyl]phenyl}-1-benzothiophene-2-carboxamide chemical structure, C20H20ClN3O3S2, CAS 712290-54-5
3-Chloro-N-{2-[4-(methylsulfonyl)-1-piperazinyl]phenyl}-1-benzothiophene-2-carboxamide
CAS 712290-54-5C20H20ClN3O3S2
3-Chloro-N-[5-chloro-2-(4-propanoylpiperazin-1-yl)phenyl]-1-benzothiophene-2-carboxamide chemical structure, C22H21Cl2N3O2S, CAS 713507-93-8
3-Chloro-N-[5-chloro-2-(4-propanoylpiperazin-1-yl)phenyl]-1-benzothiophene-2-carboxamide
CAS 713507-93-8C22H21Cl2N3O2S
3-Chloro-N-[2-(4-methyl-1-piperazinyl)phenyl]-1-benzothiophene-2-carboxamide chemical structure, C20H20ClN3OS, CAS 831199-23-6
3-Chloro-N-[2-(4-methyl-1-piperazinyl)phenyl]-1-benzothiophene-2-carboxamide
CAS 831199-23-6C20H20ClN3OS
3,6-Dichloro-N-[2-(4-propanoylpiperazin-1-yl)phenyl]-1-benzothiophene-2-carboxamide chemical structure, C22H21Cl2N3O2S, CAS 717834-17-8
3,6-Dichloro-N-[2-(4-propanoylpiperazin-1-yl)phenyl]-1-benzothiophene-2-carboxamide
CAS 717834-17-8C22H21Cl2N3O2S
N-[2-(4-Acetyl-1-piperazinyl)phenyl]-3-chloro-1-benzothiophene-2-carboxamide chemical structure, C21H20ClN3O2S, CAS 792946-36-2
N-[2-(4-Acetyl-1-piperazinyl)phenyl]-3-chloro-1-benzothiophene-2-carboxamide
CAS 792946-36-2C21H20ClN3O2S
3-Chloro-N-[2-(4-propanoylpiperazin-1-yl)phenyl]-1-benzothiophene-2-carboxamide chemical structure, C22H22ClN3O2S, CAS 694443-34-0
3-Chloro-N-[2-(4-propanoylpiperazin-1-yl)phenyl]-1-benzothiophene-2-carboxamide
CAS 694443-34-0C22H22ClN3O2S
Methyl 3-{[(3-chloro-1-benzothien-2-yl)carbonyl]amino}-4-(4-methyl-1-piperazinyl)benzoate chemical structure, C22H22ClN3O3S, CAS 890179-88-1
Methyl 3-{[(3-chloro-1-benzothien-2-yl)carbonyl]amino}-4-(4-methyl-1-piperazinyl)benzoate
CAS 890179-88-1C22H22ClN3O3S