Murcko scaffold
Benzyl(phenylsulfonyl)-2-pyridylamine scaffold
32 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 23
- Chemicals
- 32
- With full pages
- 5
Scaffold SMILES
O=S(=O)(c1ccccc1)N(Cc1ccccc1)c1ccccn1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 32 of 32 chemicals
Benzyl(phenylsulfonyl)-2-pyridylamine
CAS 330466-84-7C18H16N2O2S
![[(4-Fluorophenyl)sulfonyl]benzyl-2-pyridylamine chemical structure, C18H15FN2O2S, CAS 330467-36-2](/s/AWFHLWVOHRDJSL-UHFFFAOYSA-N.svg)
[(4-Fluorophenyl)sulfonyl]benzyl-2-pyridylamine
CAS 330467-36-2C18H15FN2O2S
N-Benzyl-4-methoxy-N-pyridin-2-ylbenzenesulfonamide
CAS 330467-02-2C19H18N2O3S
![N-[4-[Benzyl(pyridin-2-yl)sulfamoyl]phenyl]acetamide chemical structure, C20H19N3O3S, CAS 321531-93-5](/s/MDZSHFJKEJLBLV-UHFFFAOYSA-N.svg)
N-[4-[Benzyl(pyridin-2-yl)sulfamoyl]phenyl]acetamide
CAS 321531-93-5C20H19N3O3S
![4-([(Phenylsulfonyl)(pyridin-2-yl)amino]methyl)benzoic acid chemical structure, C19H16N2O4S, CAS 296772-87-7](/s/GRUBUFLJTCRPCA-UHFFFAOYSA-N.svg)
4-([(Phenylsulfonyl)(pyridin-2-yl)amino]methyl)benzoic acid
CAS 296772-87-7C19H16N2O4S
![Methyl 4-{[(phenylsulfonyl)(2-pyridinyl)amino]methyl}benzoate chemical structure, C20H18N2O4S, CAS 331750-23-3](/s/NXSFQHNKHVQUNQ-UHFFFAOYSA-N.svg)
Methyl 4-{[(phenylsulfonyl)(2-pyridinyl)amino]methyl}benzoate
CAS 331750-23-3C20H18N2O4S
![N-Benzyl-N-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]benzenesulfonamide chemical structure, C19H14ClF3N2O2S, CAS 244050-17-7](/s/YIXMUAOMXLAEIN-UHFFFAOYSA-N.svg)
N-Benzyl-N-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]benzenesulfonamide
CAS 244050-17-7C19H14ClF3N2O2S
4-(N-Benzyl-N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)sulfamoyl)benzoic acid
CAS 1254205-44-1C20H14ClF3N2O4S
![4-{Benzyl[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfamoyl}benzamide chemical structure, C20H15ClF3N3O3S, CAS 1254205-47-4](/s/RRRCPKHCAXKRRV-UHFFFAOYSA-N.svg)
4-{Benzyl[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfamoyl}benzamide
CAS 1254205-47-4C20H15ClF3N3O3S
![4-{Benzyl[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfamoyl}-N-methylbenzamide chemical structure, C21H17ClF3N3O3S, CAS 1254205-48-5](/s/NTXUMDYTLHJDCT-UHFFFAOYSA-N.svg)
4-{Benzyl[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfamoyl}-N-methylbenzamide
CAS 1254205-48-5C21H17ClF3N3O3S
![4-{Benzyl[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfamoyl}-N,N-dimethylbenzamide chemical structure, C22H19ClF3N3O3S, CAS 1254205-49-6](/s/NLTUUDOCBBASGM-UHFFFAOYSA-N.svg)
4-{Benzyl[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfamoyl}-N,N-dimethylbenzamide
CAS 1254205-49-6C22H19ClF3N3O3S
![4-{Benzyl[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfamoyl}-N-(2-hydroxyethyl)benzamide chemical structure, C22H19ClF3N3O4S, CAS 1254205-50-9](/s/TUAVQGYGMJCFLF-UHFFFAOYSA-N.svg)
4-{Benzyl[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfamoyl}-N-(2-hydroxyethyl)benzamide
CAS 1254205-50-9C22H19ClF3N3O4S
RQ-00203078
CAS 1254205-52-1C21H13ClF6N2O5S
![4-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl][(4-fluorophenyl)methyl]sulfamoyl}benzoic acid chemical structure, C20H13ClF4N2O4S, CAS 1254205-54-3](/s/WECUMEJQVKOERZ-UHFFFAOYSA-N.svg)
4-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl][(4-fluorophenyl)methyl]sulfamoyl}benzoic acid
CAS 1254205-54-3C20H13ClF4N2O4S
![4-{[(4-tert-Butylphenyl)methyl][3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfamoyl}benzoic acid chemical structure, C24H22ClF3N2O4S, CAS 1254205-55-4](/s/PMMAWGLBEYFLAA-UHFFFAOYSA-N.svg)
4-{[(4-tert-Butylphenyl)methyl][3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfamoyl}benzoic acid
CAS 1254205-55-4C24H22ClF3N2O4S
phenyl]methyl})sulfamoyl}benzoic acid chemical structure, C21H13ClF6N2O4S, CAS 1254205-60-1](/s/DJBQNOYYCPDREF-UHFFFAOYSA-N.svg)
4-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]({[3-(trifluoromethyl)phenyl]methyl})sulfamoyl}benzoic acid
CAS 1254205-60-1C21H13ClF6N2O4S
phenyl]methyl})sulfamoyl}benzoic acid chemical structure, C21H13ClF6N2O5S, CAS 1254205-62-3](/s/CRPGXZOGGKNDNJ-UHFFFAOYSA-N.svg)
4-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]({[3-(trifluoromethoxy)phenyl]methyl})sulfamoyl}benzoic acid
CAS 1254205-62-3C21H13ClF6N2O5S
phenyl]methyl})sulfamoyl}benzoic acid chemical structure, C21H13ClF6N2O4S, CAS 1254205-68-9](/s/CDRBZUVBPKPRTA-UHFFFAOYSA-N.svg)
4-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]({[2-(trifluoromethyl)phenyl]methyl})sulfamoyl}benzoic acid
CAS 1254205-68-9C21H13ClF6N2O4S
phenyl]methyl})sulfamoyl}benzoic acid chemical structure, C21H12ClF7N2O4S, CAS 1254205-80-5](/s/WJZTXQAKUXWZIU-UHFFFAOYSA-N.svg)
4-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]({[4-fluoro-3-(trifluoromethyl)phenyl]methyl})sulfamoyl}benzoic acid
CAS 1254205-80-5C21H12ClF7N2O4S
phenyl]methyl})sulfamoyl}benzoic acid chemical structure, C24H19ClF6N2O4S, CAS 1254205-87-2](/s/GVGWRROBXZESQK-UHFFFAOYSA-N.svg)
4-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]({[4-(1,1,1-trifluoro-2-methylpropan-2-yl)phenyl]methyl})sulfamoyl}benzoic acid
CAS 1254205-87-2C24H19ClF6N2O4S
N-Benzyl-4-chloro-3-methyl-N-(pyridin-2-yl)benzene-1-sulfonamide
CAS 1374679-79-4C19H17ClN2O2S
![3-{Benzyl[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfamoyl}benzoic acid chemical structure, C20H14ClF3N2O4S, CAS 1254205-89-4](/s/IEUHRUWHWSEANZ-UHFFFAOYSA-N.svg)
3-{Benzyl[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfamoyl}benzoic acid
CAS 1254205-89-4C20H14ClF3N2O4S
![4-{Benzyl[3-fluoro-5-(trifluoromethyl)pyridin-2-yl]sulfamoyl}benzoic acid chemical structure, C20H14F4N2O4S, CAS 1254205-90-7](/s/VBEONWICTOPKBL-UHFFFAOYSA-N.svg)
4-{Benzyl[3-fluoro-5-(trifluoromethyl)pyridin-2-yl]sulfamoyl}benzoic acid
CAS 1254205-90-7C20H14F4N2O4S
![4-{Benzyl[5-(trifluoromethyl)pyridin-2-yl]sulfamoyl}benzoic acid chemical structure, C20H15F3N2O4S, CAS 1254205-51-0](/s/XHYVYDXJVUCFLR-UHFFFAOYSA-N.svg)
4-{Benzyl[5-(trifluoromethyl)pyridin-2-yl]sulfamoyl}benzoic acid
CAS 1254205-51-0C20H15F3N2O4S
- N-Benzyl-N-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(hydroxymethyl)benzene-1-sulfonamide1254205-46-3C20H16ClF3N2O3S
- 6-[Benzenesulfonyl-(4-chloro-benzyl)-amino]-nicotinic acid methyl ester1255716-63-2C20H17ClN2O4S
- 6-[Benzenesulfonyl-(4-chloro-benzyl)-amino]-nicotinic acid1255716-64-3C19H15ClN2O4S
- 4-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]({[4-(trifluoromethyl)phenyl]methyl})sulfamoyl}benzoic acid1254205-76-9C21H13ClF6N2O4S
- 2-{Benzyl[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfamoyl}benzoic acid1638533-91-1C20H14ClF3N2O4S
- 4-[Benzyl(3-chloro-5-cyanopyridin-2-yl)sulfamoyl]benzoic acid1638533-96-6C20H14ClN3O4S
- 4-{Benzyl[3-cyano-5-(trifluoromethyl)pyridin-2-yl]sulfamoyl}benzoic acid1638533-97-7C21H14F3N3O4S
- 4-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl][(4-acetamidophenyl)methyl]sulfamoyl}benzoic acid1638533-99-9C22H17ClF3N3O5S
Related scaffolds
Same ring framework with different atoms or bond orders
O=S(=O)(c1ccccc1)N(Cc1ccccc1)c1ccccc131 chemicals
c1ccc(CN(Cc2ccccc2)c2ccccc2)cc111 chemicals
O=C(c1ccccc1)N(Cc1ccccc1)c1ccccc15 chemicals
c1ccc(SC(Sc2ccccc2)c2ccccc2)cc14 chemicals
c1ccc(NN(Cc2ccncc2)c2ccccc2)cc14 chemicals
O=C(c1ccccc1)N(c1ccccc1)S(=O)(=O)c1ccccc13 chemicals
c1ccc(CC(Cc2ccccc2)c2ccccc2)cc13 chemicals
c1ccc(NN(Cc2ccccn2)c2ccccc2)cc13 chemicals
O=C(c1ccccc1)C(Nc1ccccc1)c1ccccc13 chemicals
O=C(c1ccccc1)N(Cc1ccccc1)N1C(=O)CCCC1=O3 chemicals
C1CC(CC(CC2CCNCC2)C2CCNCC2)CCN12 chemicals
O=S(=O)(c1ccccc1)N(Cc1ccccc1)c1ncccn12 chemicals