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Murcko scaffold

Ring system with 2 rings and 21 atoms

32 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
21
Chemicals
32
With full pages
5
Scaffold SMILES

O=C(COc1ccccc1)NNC(=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)NNC(=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 32 of 32 chemicals

2-[(4-Methylphenoxy)acetyl]-N-phenylhydrazinecarboxamide chemical structure, C16H17N3O3, CAS 300821-58-3
2-[(4-Methylphenoxy)acetyl]-N-phenylhydrazinecarboxamide
CAS 300821-58-3C16H17N3O3
2-[(4-Chlorophenoxy)acetyl]-N-(4-methylphenyl)hydrazinecarboxamide chemical structure, C16H16ClN3O3, CAS 339528-09-5
2-[(4-Chlorophenoxy)acetyl]-N-(4-methylphenyl)hydrazinecarboxamide
CAS 339528-09-5C16H16ClN3O3
N-(3-Chlorophenyl)-2-[(2,3-dimethylphenoxy)acetyl]hydrazinecarboxamide chemical structure, C17H18ClN3O3, CAS 495395-96-5
N-(3-Chlorophenyl)-2-[(2,3-dimethylphenoxy)acetyl]hydrazinecarboxamide
CAS 495395-96-5C17H18ClN3O3
2-[(4-Chlorophenoxy)acetyl]-N-(3-methylphenyl)hydrazinecarboxamide chemical structure, C16H16ClN3O3, CAS 339528-07-3
2-[(4-Chlorophenoxy)acetyl]-N-(3-methylphenyl)hydrazinecarboxamide
CAS 339528-07-3C16H16ClN3O3
1-(2-(2,4-Dimethylphenoxy)acetyl)-4-phenylsemicarbazide chemical structure, C17H19N3O3, CAS 650630-86-7
1-(2-(2,4-Dimethylphenoxy)acetyl)-4-phenylsemicarbazide
CAS 650630-86-7C17H19N3O3
1-(4-Chlorophenyl)-3-[[2-(4-methoxyphenoxy)acetyl]amino]urea chemical structure, C16H16ClN3O4, CAS 648915-34-8
1-(4-Chlorophenyl)-3-[[2-(4-methoxyphenoxy)acetyl]amino]urea
CAS 648915-34-8C16H16ClN3O4
N-(4-Chlorophenyl)-2-[(2,5-dichlorophenoxy)acetyl]hydrazinecarboxamide chemical structure, C15H12Cl3N3O3, CAS 495386-34-0
N-(4-Chlorophenyl)-2-[(2,5-dichlorophenoxy)acetyl]hydrazinecarboxamide
CAS 495386-34-0C15H12Cl3N3O3
2-[(2,4-Dichlorophenoxy)acetyl]-N-(3-methylphenyl)hydrazinecarboxamide chemical structure, C16H15Cl2N3O3, CAS 445007-88-5
2-[(2,4-Dichlorophenoxy)acetyl]-N-(3-methylphenyl)hydrazinecarboxamide
CAS 445007-88-5C16H15Cl2N3O3
1-[[2-(4-Chloro-2-methylphenoxy)acetyl]amino]-3-(3,4-dimethoxyphenyl)urea chemical structure, C18H20ClN3O5, CAS 701281-15-4
1-[[2-(4-Chloro-2-methylphenoxy)acetyl]amino]-3-(3,4-dimethoxyphenyl)urea
CAS 701281-15-4C18H20ClN3O5
1-[[2-(2-Chloro-5-methylphenoxy)acetyl]amino]-3-(2,4-dichlorophenyl)urea chemical structure, C16H14Cl3N3O3, CAS 701929-67-1
1-[[2-(2-Chloro-5-methylphenoxy)acetyl]amino]-3-(2,4-dichlorophenyl)urea
CAS 701929-67-1C16H14Cl3N3O3
1-[[2-(2,4-Difluorophenoxy)acetyl]amino]-3-(2,5-dimethoxyphenyl)urea chemical structure, C17H17F2N3O5, CAS 701933-96-2
1-[[2-(2,4-Difluorophenoxy)acetyl]amino]-3-(2,5-dimethoxyphenyl)urea
CAS 701933-96-2C17H17F2N3O5
1-(4-Acetylphenyl)-3-[[2-(2,4,5-trichlorophenoxy)acetyl]amino]urea chemical structure, C17H14Cl3N3O4, CAS 708229-26-9
1-(4-Acetylphenyl)-3-[[2-(2,4,5-trichlorophenoxy)acetyl]amino]urea
CAS 708229-26-9C17H14Cl3N3O4
1-(2-Methoxy-5-methylphenyl)-3-[2-(4-nitrophenoxy)propanoylamino]urea chemical structure, C18H20N4O6, CAS 701930-69-0
1-(2-Methoxy-5-methylphenyl)-3-[2-(4-nitrophenoxy)propanoylamino]urea
CAS 701930-69-0C18H20N4O6
1-[2-(2,4-Dichlorophenoxy)propanoylamino]-3-(2,5-dimethoxyphenyl)urea chemical structure, C18H19Cl2N3O5, CAS 701953-34-6
1-[2-(2,4-Dichlorophenoxy)propanoylamino]-3-(2,5-dimethoxyphenyl)urea
CAS 701953-34-6C18H19Cl2N3O5
1-(4-Ethoxyphenyl)-3-[[2-(4-ethylphenoxy)acetyl]amino]urea chemical structure, C19H23N3O4, CAS 892834-47-8
1-(4-Ethoxyphenyl)-3-[[2-(4-ethylphenoxy)acetyl]amino]urea
CAS 892834-47-8C19H23N3O4
1-(2-(4-Trifluoromethoxyphenoxy)acetyl)-4-(2-chlorophenyl)semicarbazide chemical structure, C16H13ClF3N3O4, CAS 1022454-89-2
1-(2-(4-Trifluoromethoxyphenoxy)acetyl)-4-(2-chlorophenyl)semicarbazide
CAS 1022454-89-2C16H13ClF3N3O4
N-((Phenylamino)carbonylamino)-2-(3-(trifluoromethyl)phenoxy)ethanamide chemical structure, C16H14F3N3O3, CAS 891018-44-3
N-((Phenylamino)carbonylamino)-2-(3-(trifluoromethyl)phenoxy)ethanamide
CAS 891018-44-3C16H14F3N3O3
2-(4-Bromo-3,5-dimethylphenoxy)-N-((N-(4-(trifluoromethyl)phenyl)carbamoyl)amino)ethanamide chemical structure, C18H17BrF3N3O3, CAS 1022288-03-4
2-(4-Bromo-3,5-dimethylphenoxy)-N-((N-(4-(trifluoromethyl)phenyl)carbamoyl)amino)ethanamide
CAS 1022288-03-4C18H17BrF3N3O3
1-[[2-(4-Nitrophenoxy)acetyl]amino]-3-[3-(trifluoromethyl)phenyl]urea chemical structure, C16H13F3N4O5, CAS 905371-34-8
1-[[2-(4-Nitrophenoxy)acetyl]amino]-3-[3-(trifluoromethyl)phenyl]urea
CAS 905371-34-8C16H13F3N4O5
1-(2-(4-Ethylphenoxy)acetyl)-4-(5-chloro-2-methoxyphenyl)semicarbazide chemical structure, C18H20ClN3O4, CAS 904197-37-1
1-(2-(4-Ethylphenoxy)acetyl)-4-(5-chloro-2-methoxyphenyl)semicarbazide
CAS 904197-37-1C18H20ClN3O4
1-(2-(2,4-Dichlorophenoxy)propionyl)-4-(3-(trifluoromethyl)phenyl)semicarbazide chemical structure, C17H14Cl2F3N3O3, CAS 894955-04-5
1-(2-(2,4-Dichlorophenoxy)propionyl)-4-(3-(trifluoromethyl)phenyl)semicarbazide
CAS 894955-04-5C17H14Cl2F3N3O3
1-(2-(4-Ethylphenoxy)acetyl)-4-(3-trifluoromethylphenyl)semicarbazide chemical structure, C18H18F3N3O3, CAS 905371-43-9
1-(2-(4-Ethylphenoxy)acetyl)-4-(3-trifluoromethylphenyl)semicarbazide
CAS 905371-43-9C18H18F3N3O3
1-(2-(4-Ethylphenoxy)acetyl)-4-(2-ethoxyphenyl)semicarbazide chemical structure, C19H23N3O4, CAS 892834-41-2
1-(2-(4-Ethylphenoxy)acetyl)-4-(2-ethoxyphenyl)semicarbazide
CAS 892834-41-2C19H23N3O4
1-(2-(4-Bromophenoxy)acetyl)-4-(4-chlorophenyl)semicarbazide chemical structure, C15H13BrClN3O3, CAS 448251-28-3
1-(2-(4-Bromophenoxy)acetyl)-4-(4-chlorophenyl)semicarbazide
CAS 448251-28-3C15H13BrClN3O3