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Murcko scaffold

N-((5-((2-Oxo-2-(thiazol-2-ylamino)ethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide scaffold

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
11
With full pages
1
Scaffold SMILES

O=C(CSc1nnc(CNC(=O)c2ccccc2)o1)Nc1nccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-((5-((2-Oxo-2-(thiazol-2-ylamino)ethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide page
Murcko scaffold O=C(CSc1nnc(CNC(=O)c2ccccc2)o1)Nc1nccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

2-Chloro-6-fluoro-N-((5-((2-oxo-2-(thiazol-2-ylamino)ethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide chemical structure, C15H11ClFN5O3S2, CAS 851860-51-0
2-Chloro-6-fluoro-N-((5-((2-oxo-2-(thiazol-2-ylamino)ethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide
CAS 851860-51-0C15H11ClFN5O3S2
4-Methoxy-N-((5-((2-oxo-2-(thiazol-2-ylamino)ethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide chemical structure, C16H15N5O4S2, CAS 851783-65-8
4-Methoxy-N-((5-((2-oxo-2-(thiazol-2-ylamino)ethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide
CAS 851783-65-8C16H15N5O4S2
3,4-Dimethoxy-N-((5-((2-oxo-2-(thiazol-2-ylamino)ethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide chemical structure, C17H17N5O5S2, CAS 851862-84-5
3,4-Dimethoxy-N-((5-((2-oxo-2-(thiazol-2-ylamino)ethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide
CAS 851862-84-5C17H17N5O5S2
3,4,5-Trimethoxy-N-((5-((2-oxo-2-(thiazol-2-ylamino)ethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide chemical structure, C18H19N5O6S2, CAS 851784-31-1
3,4,5-Trimethoxy-N-((5-((2-oxo-2-(thiazol-2-ylamino)ethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide
CAS 851784-31-1C18H19N5O6S2
N-((5-((2-Oxo-2-(thiazol-2-ylamino)ethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide chemical structure, C15H13N5O3S2, CAS 872613-57-5
N-((5-((2-Oxo-2-(thiazol-2-ylamino)ethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide
CAS 872613-57-5C15H13N5O3S2
4-Fluoro-N-((5-((2-oxo-2-(thiazol-2-ylamino)ethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide chemical structure, C15H12FN5O3S2, CAS 903269-31-8
4-Fluoro-N-((5-((2-oxo-2-(thiazol-2-ylamino)ethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide
CAS 903269-31-8C15H12FN5O3S2
4-Fluoro-N-((5-((2-((4-methylthiazol-2-yl)amino)-2-oxoethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide chemical structure, C16H14FN5O3S2, CAS 906155-17-7
4-Fluoro-N-((5-((2-((4-methylthiazol-2-yl)amino)-2-oxoethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide
CAS 906155-17-7C16H14FN5O3S2
N-((5-((2-((4-Methylthiazol-2-yl)amino)-2-oxoethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)-3-(trifluoromethyl)benzamide chemical structure, C17H14F3N5O3S2, CAS 872620-89-8
N-((5-((2-((4-Methylthiazol-2-yl)amino)-2-oxoethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)-3-(trifluoromethyl)benzamide
CAS 872620-89-8C17H14F3N5O3S2
2-Methyl-3-nitro-N-((5-((2-oxo-2-(thiazol-2-ylamino)ethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide chemical structure, C16H14N6O5S2, CAS 903271-97-6
2-Methyl-3-nitro-N-((5-((2-oxo-2-(thiazol-2-ylamino)ethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide
CAS 903271-97-6C16H14N6O5S2
2-Methyl-N-((5-((2-((4-methylthiazol-2-yl)amino)-2-oxoethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)-3-nitrobenzamide chemical structure, C17H16N6O5S2, CAS 903315-34-4
2-Methyl-N-((5-((2-((4-methylthiazol-2-yl)amino)-2-oxoethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)-3-nitrobenzamide
CAS 903315-34-4C17H16N6O5S2
4-(N,N-Dimethylsulfamoyl)-N-((5-((2-((4-methylthiazol-2-yl)amino)-2-oxoethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide chemical structure, C18H20N6O5S3, CAS 1396885-73-6
4-(N,N-Dimethylsulfamoyl)-N-((5-((2-((4-methylthiazol-2-yl)amino)-2-oxoethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide
CAS 1396885-73-6C18H20N6O5S3