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Murcko scaffold

2-[4-(Furan-2-carbonyl)piperazin-1-yl]-N-phenylacetamide scaffold

20 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 23
Chemicals: 20
With full pages: 10

Scaffold SMILES

O=C(CN1CCN(C(=O)c2ccco2)CC1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-[4-(Furan-2-carbonyl)piperazin-1-yl]-N-phenylacetamide page

Murcko scaffold O=C(CN1CCN(C(=O)c2ccco2)CC1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

N-(3,5-Dimethylphenyl)-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide chemical structure, C19H23N3O3, CAS 333758-64-8

N-(3,5-Dimethylphenyl)-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide

CAS 333758-64-8C₁₉H₂₃N₃O₃

2-[4-(Furan-2-carbonyl)piperazin-1-yl]-N-phenylacetamide chemical structure, C17H19N3O3, CAS 333758-62-6

2-[4-(Furan-2-carbonyl)piperazin-1-yl]-N-phenylacetamide

CAS 333758-62-6C₁₇H₁₉N₃O₃

2-[4-(Furan-2-carbonyl)piperazin-1-yl]-N-(4-methylphenyl)acetamide chemical structure, C18H21N3O3, CAS 432519-36-3

2-[4-(Furan-2-carbonyl)piperazin-1-yl]-N-(4-methylphenyl)acetamide

CAS 432519-36-3C₁₈H₂₁N₃O₃

2-[4-(Furan-2-carbonyl)piperazin-1-yl]-N-(4-methoxyphenyl)acetamide chemical structure, C18H21N3O4, CAS 1062137-17-0

2-[4-(Furan-2-carbonyl)piperazin-1-yl]-N-(4-methoxyphenyl)acetamide

CAS 1062137-17-0C₁₈H₂₁N₃O₄

N-(2,5-Dichloro-phenyl)-2-[4-(furan-2-carbonyl)-piperazin-1-yl]-acetamide chemical structure, C17H17Cl2N3O3, CAS 700851-16-7

N-(2,5-Dichloro-phenyl)-2-[4-(furan-2-carbonyl)-piperazin-1-yl]-acetamide

CAS 700851-16-7C₁₇H₁₇Cl₂N₃O₃

N-(4-Bromophenyl)-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide chemical structure, C17H18BrN3O3, CAS 519041-49-7

N-(4-Bromophenyl)-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide

CAS 519041-49-7C₁₇H₁₈BrN₃O₃

N-(4-Chloro-2-methyl-phenyl)-2-[4-(furan-2-carbonyl)-piperazin-1-yl]-acetamide chemical structure, C18H20ClN3O3, CAS 333758-63-7

N-(4-Chloro-2-methyl-phenyl)-2-[4-(furan-2-carbonyl)-piperazin-1-yl]-acetamide

CAS 333758-63-7C₁₈H₂₀ClN₃O₃

N-(3,5-Dichlorophenyl)-2-[4-(furan-2-ylcarbonyl)piperazin-1-yl]acetamide chemical structure, C17H17Cl2N3O3, CAS 404856-14-0

N-(3,5-Dichlorophenyl)-2-[4-(furan-2-ylcarbonyl)piperazin-1-yl]acetamide

CAS 404856-14-0C₁₇H₁₇Cl₂N₃O₃

2-[4-(Furan-2-carbonyl)piperazin-1-yl]-N-(2-methoxyphenyl)acetamide chemical structure, C18H21N3O4, CAS 835598-85-1

2-[4-(Furan-2-carbonyl)piperazin-1-yl]-N-(2-methoxyphenyl)acetamide

CAS 835598-85-1C₁₈H₂₁N₃O₄

N-(2,4-Dimethoxyphenyl)-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide chemical structure, C19H23N3O5, CAS 835598-98-6

N-(2,4-Dimethoxyphenyl)-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide

CAS 835598-98-6C₁₉H₂₃N₃O₅

N-(3,4-Dichlorophenyl)-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide chemical structure, C17H17Cl2N3O3, CAS 900604-12-8

N-(3,4-Dichlorophenyl)-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide

CAS 900604-12-8C₁₇H₁₇Cl₂N₃O₃

N-[3,5-Bis(trifluoromethyl)phenyl]-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide chemical structure, C19H17F6N3O3, CAS 839681-24-2

N-[3,5-Bis(trifluoromethyl)phenyl]-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide

CAS 839681-24-2C₁₉H₁₇F₆N₃O₃

RefChem:1089769 chemical structure, C18H17ClF3N3O3, CAS 899713-86-1

RefChem:1089769

CAS 899713-86-1C₁₈H₁₇ClF₃N₃O₃

2-[4-(Furan-2-carbonyl)piperazin-1-yl]-N-(3-methoxyphenyl)acetamide chemical structure, C18H21N3O4, CAS 902728-69-2

2-[4-(Furan-2-carbonyl)piperazin-1-yl]-N-(3-methoxyphenyl)acetamide

CAS 902728-69-2C₁₈H₂₁N₃O₄

N-(4-Ethoxyphenyl)-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide chemical structure, C19H23N3O4, CAS 902733-03-3

N-(4-Ethoxyphenyl)-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide

CAS 902733-03-3C₁₉H₂₃N₃O₄

N-(4-Bromo-2-chlorophenyl)-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide chemical structure, C17H17BrClN3O3, CAS 902732-50-7

N-(4-Bromo-2-chlorophenyl)-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide

CAS 902732-50-7C₁₇H₁₇BrClN₃O₃

N-(2,4-Dichlorophenyl)-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide chemical structure, C17H17Cl2N3O3, CAS 900604-08-2

N-(2,4-Dichlorophenyl)-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide

CAS 900604-08-2C₁₇H₁₇Cl₂N₃O₃

N-(5-Chloro-2-methylphenyl)-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide chemical structure, C18H20ClN3O3, CAS 902733-70-4

N-(5-Chloro-2-methylphenyl)-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide

CAS 902733-70-4C₁₈H₂₀ClN₃O₃

2-[4-(Furan-2-carbonyl)piperazin-1-yl]-N-(2-methylphenyl)acetamide chemical structure, C18H21N3O3, CAS 902728-06-7

2-[4-(Furan-2-carbonyl)piperazin-1-yl]-N-(2-methylphenyl)acetamide

CAS 902728-06-7C₁₈H₂₁N₃O₃

N-(2-Cyanophenyl)-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide chemical structure, C18H18N4O3, CAS 1083198-99-5

N-(2-Cyanophenyl)-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide

CAS 1083198-99-5C₁₈H₁₈N₄O₃