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Murcko scaffold

Ring system with 3 rings and 21 atoms

35 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
35
With full pages
6
Scaffold SMILES

O=C(Nc1ccccc1)C1(c2ccccc2)CCOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)C1(c2ccccc2)CCOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 35 of 35 chemicals

N-(4-Fluorophenyl)-4-phenyloxane-4-carboxamide chemical structure, C18H18FNO2, CAS 682760-44-7
N-(4-Fluorophenyl)-4-phenyloxane-4-carboxamide
CAS 682760-44-7C18H18FNO2
4-Phenyl-N-[3-(trifluoromethyl)phenyl]oxane-4-carboxamide chemical structure, C19H18F3NO2, CAS 682760-46-9
4-Phenyl-N-[3-(trifluoromethyl)phenyl]oxane-4-carboxamide
CAS 682760-46-9C19H18F3NO2
N-(2-Chlorophenyl)-4-phenyloxane-4-carboxamide chemical structure, C18H18ClNO2, CAS 371226-08-3
N-(2-Chlorophenyl)-4-phenyloxane-4-carboxamide
CAS 371226-08-3C18H18ClNO2
N-(3-Methylphenyl)-4-phenyloxane-4-carboxamide chemical structure, C19H21NO2, CAS 431979-68-9
N-(3-Methylphenyl)-4-phenyloxane-4-carboxamide
CAS 431979-68-9C19H21NO2
N-(4-Methylphenyl)-4-phenyloxane-4-carboxamide chemical structure, C19H21NO2, CAS 432021-27-7
N-(4-Methylphenyl)-4-phenyloxane-4-carboxamide
CAS 432021-27-7C19H21NO2
N-(2-Methoxyphenyl)-4-phenyloxane-4-carboxamide chemical structure, C19H21NO3, CAS 355820-68-7
N-(2-Methoxyphenyl)-4-phenyloxane-4-carboxamide
CAS 355820-68-7C19H21NO3
N-(4-Acetylphenyl)-4-phenyloxane-4-carboxamide chemical structure, C20H21NO3, CAS 512795-86-7
N-(4-Acetylphenyl)-4-phenyloxane-4-carboxamide
CAS 512795-86-7C20H21NO3
N-(2-Methoxy-5-methylphenyl)-4-phenyloxane-4-carboxamide chemical structure, C20H23NO3, CAS 692262-38-7
N-(2-Methoxy-5-methylphenyl)-4-phenyloxane-4-carboxamide
CAS 692262-38-7C20H23NO3
N-(4-Methoxyphenyl)-4-phenyloxane-4-carboxamide chemical structure, C19H21NO3, CAS 332391-81-8
N-(4-Methoxyphenyl)-4-phenyloxane-4-carboxamide
CAS 332391-81-8C19H21NO3
N-(2-Methoxyphenyl)-4-(4-methoxyphenyl)oxane-4-carboxamide chemical structure, C20H23NO4, CAS 664971-08-8
N-(2-Methoxyphenyl)-4-(4-methoxyphenyl)oxane-4-carboxamide
CAS 664971-08-8C20H23NO4
N-(3-Chlorophenyl)-4-phenyloxane-4-carboxamide chemical structure, C18H18ClNO2, CAS 713099-45-7
N-(3-Chlorophenyl)-4-phenyloxane-4-carboxamide
CAS 713099-45-7C18H18ClNO2
N-(2-Methoxy-5-methylphenyl)-4-(4-methoxyphenyl)oxane-4-carboxamide chemical structure, C21H25NO4, CAS 664993-29-7
N-(2-Methoxy-5-methylphenyl)-4-(4-methoxyphenyl)oxane-4-carboxamide
CAS 664993-29-7C21H25NO4
N-(4-Bromophenyl)-4-(4-methoxyphenyl)oxane-4-carboxamide chemical structure, C19H20BrNO3, CAS 664993-45-7
N-(4-Bromophenyl)-4-(4-methoxyphenyl)oxane-4-carboxamide
CAS 664993-45-7C19H20BrNO3
Ethyl 4-({[4-(3,4-dimethoxyphenyl)tetrahydro-2H-pyran-4-yl]carbonyl}amino)benzoate chemical structure, C23H27NO6, CAS 428831-88-3
Ethyl 4-({[4-(3,4-dimethoxyphenyl)tetrahydro-2H-pyran-4-yl]carbonyl}amino)benzoate
CAS 428831-88-3C23H27NO6
4-(3,4-Dimethoxyphenyl)-N-(4-methoxyphenyl)tetrahydro-2H-pyran-4-carboxamide chemical structure, C21H25NO5, CAS 433953-45-8
4-(3,4-Dimethoxyphenyl)-N-(4-methoxyphenyl)tetrahydro-2H-pyran-4-carboxamide
CAS 433953-45-8C21H25NO5
4-(3,4-Dimethoxyphenyl)-N-(2-methoxyphenyl)oxane-4-carboxamide chemical structure, C21H25NO5, CAS 428837-24-5
4-(3,4-Dimethoxyphenyl)-N-(2-methoxyphenyl)oxane-4-carboxamide
CAS 428837-24-5C21H25NO5
N-(3-Methoxyphenyl)-4-phenyltetrahydro-2H-pyran-4-carboxamide chemical structure, C19H21NO3, CAS 432013-06-4
N-(3-Methoxyphenyl)-4-phenyltetrahydro-2H-pyran-4-carboxamide
CAS 432013-06-4C19H21NO3
N-(4-Bromophenyl)-4-phenyltetrahydro-2H-pyran-4-carboxamide chemical structure, C18H18BrNO2, CAS 431984-51-9
N-(4-Bromophenyl)-4-phenyltetrahydro-2H-pyran-4-carboxamide
CAS 431984-51-9C18H18BrNO2
4-(3,4-Dimethoxyphenyl)-N-(3-methoxyphenyl)oxane-4-carboxamide chemical structure, C21H25NO5, CAS 664971-17-9
4-(3,4-Dimethoxyphenyl)-N-(3-methoxyphenyl)oxane-4-carboxamide
CAS 664971-17-9C21H25NO5
4-(3,4-Dimethoxyphenyl)-N-(2-methylphenyl)oxane-4-carboxamide chemical structure, C21H25NO4, CAS 664971-19-1
4-(3,4-Dimethoxyphenyl)-N-(2-methylphenyl)oxane-4-carboxamide
CAS 664971-19-1C21H25NO4
4-(3,4-Dimethoxyphenyl)-N-[3-(trifluoromethyl)phenyl]oxane-4-carboxamide chemical structure, C21H22F3NO4, CAS 664971-23-7
4-(3,4-Dimethoxyphenyl)-N-[3-(trifluoromethyl)phenyl]oxane-4-carboxamide
CAS 664971-23-7C21H22F3NO4
N-(3-Bromophenyl)-4-phenyloxane-4-carboxamide chemical structure, C18H18BrNO2, CAS 864935-71-7
N-(3-Bromophenyl)-4-phenyloxane-4-carboxamide
CAS 864935-71-7C18H18BrNO2
N-(3-Chloro-4-methylphenyl)-4-(4-methoxyphenyl)oxane-4-carboxamide chemical structure, C20H22ClNO3, CAS 700859-91-2
N-(3-Chloro-4-methylphenyl)-4-(4-methoxyphenyl)oxane-4-carboxamide
CAS 700859-91-2C20H22ClNO3
4-({[4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-yl]carbonyl}amino)benzoic acid chemical structure, C20H21NO5, CAS 695170-22-0
4-({[4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-yl]carbonyl}amino)benzoic acid
CAS 695170-22-0C20H21NO5