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Murcko scaffold

1H-1,5-Benzodiazepine scaffold

22 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
22
With full pages
4
Scaffold SMILES

C1=CNc2ccccc2N=C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1H-1,5-Benzodiazepine page
Murcko scaffold C1=CNc2ccccc2N=C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

7-Chloro-2,4-dimethyl-1H-1,5-benzodiazepine chemical structure, C11H11ClN2, CAS 6286-66-4
7-Chloro-2,4-dimethyl-1H-1,5-benzodiazepine
CAS 6286-66-4C11H11ClN2
2,4-Dimethyl-1H-1,5-benzodiazepine chemical structure, C11H12N2, CAS 48134-38-9
2,4-Dimethyl-1H-1,5-benzodiazepine
CAS 48134-38-9C11H12N2
7,8-Dimethoxy-2,4-dimethyl-1H-1,5-benzodiazepine chemical structure, C13H16N2O2, CAS 6286-55-1
7,8-Dimethoxy-2,4-dimethyl-1H-1,5-benzodiazepine
CAS 6286-55-1C13H16N2O2
1H-1,5-Benzodiazepine chemical structure, C9H8N2, CAS 265-02-1
1H-1,5-Benzodiazepine
CAS 265-02-1C9H8N2
2,4,8-Trimethyl-1H-benzo[b][1,4]diazepine chemical structure, C12H14N2, CAS 117566-70-8
2,4,8-Trimethyl-1H-benzo[b][1,4]diazepine
CAS 117566-70-8C12H14N2
8-Methoxy-2,4-dimethyl-1H-1,5-benzodiazepine chemical structure, C12H14N2O, CAS 944522-53-6
8-Methoxy-2,4-dimethyl-1H-1,5-benzodiazepine
CAS 944522-53-6C12H14N2O
Ethyl 4-amino-2-ethyl-1H-1,5-benzodiazepine-3-carboxylate chemical structure, C14H17N3O2, CAS 726153-48-6
Ethyl 4-amino-2-ethyl-1H-1,5-benzodiazepine-3-carboxylate
CAS 726153-48-6C14H17N3O2
1H-1,5-Benzodiazepine, 2,4-dimethyl-7-nitro- chemical structure, C11H11N3O2, CAS 125910-77-2
1H-1,5-Benzodiazepine, 2,4-dimethyl-7-nitro-
CAS 125910-77-2C11H11N3O2
Ethyl 4-amino-2-methyl-1H-1,5-benzodiazepine-3-carboxylate chemical structure, C13H15N3O2, CAS 726154-63-8
Ethyl 4-amino-2-methyl-1H-1,5-benzodiazepine-3-carboxylate
CAS 726154-63-8C13H15N3O2
2,4-Dimethyl-1H-1,5-benzodiazepine-7-carboxylic acid chemical structure, C12H12N2O2, CAS 655247-11-3
2,4-Dimethyl-1H-1,5-benzodiazepine-7-carboxylic acid
CAS 655247-11-3C12H12N2O2
2,4-Dimethyl-1H-1,5-benzodiazepine hydrochloride chemical structure, C11H13ClN2, CAS 58413-99-3
2,4-Dimethyl-1H-1,5-benzodiazepine hydrochloride
CAS 58413-99-3C11H13ClN2
5H-1,5-Benzodiazepin-1-ium chloride chemical structure, C9H9ClN2, CAS 65132-18-5
5H-1,5-Benzodiazepin-1-ium chloride
CAS 65132-18-5C9H9ClN2
Methyl (4-{[2-oxo-2-(propylamino)ethyl]thio}-1H-1,5-benzodiazepin-2-yl)acetate chemical structure, C17H21N3O3S, CAS 1251676-23-9
Methyl (4-{[2-oxo-2-(propylamino)ethyl]thio}-1H-1,5-benzodiazepin-2-yl)acetate
CAS 1251676-23-9C17H21N3O3S
3-[4-(Difluoromethyl)-1H-1,5-benzodiazepin-2-yl]-1,1-difluoropropan-2-one chemical structure, C13H10F4N2O, CAS 748794-20-9
3-[4-(Difluoromethyl)-1H-1,5-benzodiazepin-2-yl]-1,1-difluoropropan-2-one
CAS 748794-20-9C13H10F4N2O
Acetic acid--2,4-dimethyl-1H-1,5-benzodiazepine (1/1) chemical structure, C13H16N2O2, CAS 4485-90-9
Acetic acid--2,4-dimethyl-1H-1,5-benzodiazepine (1/1)
CAS 4485-90-9C13H16N2O2
Sulfuric acid--7,8-dibromo-2,4-dimethyl-1H-1,5-benzodiazepine (1/1) chemical structure, C11H12Br2N2O4S, CAS 62219-07-2
Sulfuric acid--7,8-dibromo-2,4-dimethyl-1H-1,5-benzodiazepine (1/1)
CAS 62219-07-2C11H12Br2N2O4S
2,3,4-Trimethyl-1H-1,5-benzodiazepine chemical structure, C12H14N2, CAS 91565-72-9
2,3,4-Trimethyl-1H-1,5-benzodiazepine
CAS 91565-72-9C12H14N2
2-Imino-2,5-dihydro-1H-1,5-benzodiazepine-3-carbonitrile chemical structure, C10H8N4, CAS 42510-46-3
2-Imino-2,5-dihydro-1H-1,5-benzodiazepine-3-carbonitrile
CAS 42510-46-3C10H8N4
Ethyl 2-imino-2,5-dihydro-1H-1,5-benzodiazepine-3-carboxylate chemical structure, C12H13N3O2, CAS 78842-07-6
Ethyl 2-imino-2,5-dihydro-1H-1,5-benzodiazepine-3-carboxylate
CAS 78842-07-6C12H13N3O2
2-Amino-4-(methylsulfanyl)-1H-1,5-benzodiazepine-3-carbonitrile chemical structure, C11H10N4S, CAS 827599-09-7
2-Amino-4-(methylsulfanyl)-1H-1,5-benzodiazepine-3-carbonitrile
CAS 827599-09-7C11H10N4S
2-(3,3,3-Trifluoroacetonyl)-4-trifluoromethyl-1H-benzo-[b]-1,4-diazepine chemical structure, C13H8F6N2O, CAS 2374758-31-1
2-(3,3,3-Trifluoroacetonyl)-4-trifluoromethyl-1H-benzo-[b]-1,4-diazepine
CAS 2374758-31-1C13H8F6N2O
6TT3C49Tkx chemical structure, C12H14ClN3O2, CAS 42510-47-4
6TT3C49Tkx
CAS 42510-47-4C12H14ClN3O2