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Murcko scaffold

Ring system with 4 rings and 26 atoms

14 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
14
With full pages
4
Scaffold SMILES

O=C(Nc1ccc(N2CCNCC2)cc1)c1ccc(-c2ccccc2)o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(N2CCNCC2)cc1)c1ccc(-c2ccccc2)o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

5-(4-Bromophenyl)-N-[4-(4-methylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C22H22BrN3O2, CAS 577766-40-6
5-(4-Bromophenyl)-N-[4-(4-methylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 577766-40-6C22H22BrN3O2
N-[4-(4-Acetylpiperazin-1-yl)phenyl]-5-(4-bromophenyl)furan-2-carboxamide chemical structure, C23H22BrN3O3, CAS 832122-61-9
N-[4-(4-Acetylpiperazin-1-yl)phenyl]-5-(4-bromophenyl)furan-2-carboxamide
CAS 832122-61-9C23H22BrN3O3
5-(2,5-Dichlorophenyl)-N-[4-(4-methylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C22H21Cl2N3O2, CAS 689747-72-6
5-(2,5-Dichlorophenyl)-N-[4-(4-methylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 689747-72-6C22H21Cl2N3O2
N-[4-(4-Methylpiperazin-1-yl)phenyl]-5-(3-nitrophenyl)furan-2-carboxamide chemical structure, C22H22N4O4, CAS 577766-21-3
N-[4-(4-Methylpiperazin-1-yl)phenyl]-5-(3-nitrophenyl)furan-2-carboxamide
CAS 577766-21-3C22H22N4O4
5-(4-Chlorophenyl)-N-[4-(4-methyl-1-piperazinyl)phenyl]-2-furancarboxamide chemical structure, C22H22ClN3O2, CAS 573950-09-1
5-(4-Chlorophenyl)-N-[4-(4-methyl-1-piperazinyl)phenyl]-2-furancarboxamide
CAS 573950-09-1C22H22ClN3O2
5-(4-Chlorophenyl)-N-{4-[4-(methylsulfonyl)-1-piperazinyl]phenyl}-2-furamide chemical structure, C22H22ClN3O4S, CAS 832679-24-0
5-(4-Chlorophenyl)-N-{4-[4-(methylsulfonyl)-1-piperazinyl]phenyl}-2-furamide
CAS 832679-24-0C22H22ClN3O4S
5-(2,4-Dichlorophenyl)-N-[4-(4-methylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C22H21Cl2N3O2, CAS 836666-49-0
5-(2,4-Dichlorophenyl)-N-[4-(4-methylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 836666-49-0C22H21Cl2N3O2
N-[4-(4-Butanoylpiperazin-1-yl)-3-chlorophenyl]-5-(4-chlorophenyl)furan-2-carboxamide chemical structure, C25H25Cl2N3O3, CAS 674306-83-3
N-[4-(4-Butanoylpiperazin-1-yl)-3-chlorophenyl]-5-(4-chlorophenyl)furan-2-carboxamide
CAS 674306-83-3C25H25Cl2N3O3
N-[3-Chloro-4-(4-ethylpiperazin-1-yl)phenyl]-5-(3-chlorophenyl)furan-2-carboxamide chemical structure, C23H23Cl2N3O2, CAS 674365-80-1
N-[3-Chloro-4-(4-ethylpiperazin-1-yl)phenyl]-5-(3-chlorophenyl)furan-2-carboxamide
CAS 674365-80-1C23H23Cl2N3O2
N-[3-Chloro-4-(4-methylpiperazin-1-yl)phenyl]-5-(2,4-dichlorophenyl)furan-2-carboxamide chemical structure, C22H20Cl3N3O2, CAS 895640-20-7
N-[3-Chloro-4-(4-methylpiperazin-1-yl)phenyl]-5-(2,4-dichlorophenyl)furan-2-carboxamide
CAS 895640-20-7C22H20Cl3N3O2
N-[4-(4-Methylsulfonylpiperazin-1-yl)phenyl]-5-(3-nitrophenyl)furan-2-carboxamide chemical structure, C22H22N4O6S, CAS 792946-77-1
N-[4-(4-Methylsulfonylpiperazin-1-yl)phenyl]-5-(3-nitrophenyl)furan-2-carboxamide
CAS 792946-77-1C22H22N4O6S
5-(4-Chlorophenyl)-N-[4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]furan-2-carboxamide chemical structure, C25H26ClN3O3, CAS 832095-57-5
5-(4-Chlorophenyl)-N-[4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]furan-2-carboxamide
CAS 832095-57-5C25H26ClN3O3
5-(4-Chlorophenyl)-N-[4-(4-propanoylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C24H24ClN3O3, CAS 835894-80-9
5-(4-Chlorophenyl)-N-[4-(4-propanoylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 835894-80-9C24H24ClN3O3
N-[4-(4-Acetylpiperazin-1-yl)phenyl]-5-(3-fluorophenyl)furan-2-carboxamide chemical structure, C23H22FN3O3, CAS 895338-10-0
N-[4-(4-Acetylpiperazin-1-yl)phenyl]-5-(3-fluorophenyl)furan-2-carboxamide
CAS 895338-10-0C23H22FN3O3