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Murcko scaffold

Tetrantoin scaffold

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
15
With full pages
2
Scaffold SMILES

O=C1NC(=O)C2(CCc3ccccc3C2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Tetrantoin page
Murcko scaffold O=C1NC(=O)C2(CCc3ccccc3C2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

Tetrantoin chemical structure, C12H12N2O2, CAS 52094-70-9
Tetrantoin
CAS 52094-70-9C12H12N2O2
2-Spirohydantoin-6,7-dimethoxytetrahydronaphthalene chemical structure, C14H16N2O4, CAS 35485-64-4
2-Spirohydantoin-6,7-dimethoxytetrahydronaphthalene
CAS 35485-64-4C14H16N2O4
Spiro(imidazolidine-4,2'(1'H)-naphthalene)-2,5-dione, 3',4'-dihydro-7'-methoxy- chemical structure, C13H14N2O3, CAS 35485-63-3
Spiro(imidazolidine-4,2'(1'H)-naphthalene)-2,5-dione, 3',4'-dihydro-7'-methoxy-
CAS 35485-63-3C13H14N2O3
Ethyl 2-(2',5'-dioxospiro[2,4-dihydro-1H-naphthalene-3,4'-imidazolidine]-1'-yl)acetate chemical structure, C16H18N2O4, CAS 968-76-3
Ethyl 2-(2',5'-dioxospiro[2,4-dihydro-1H-naphthalene-3,4'-imidazolidine]-1'-yl)acetate
CAS 968-76-3C16H18N2O4
RefChem:357342 chemical structure, C14H16N2O4, CAS 86264-49-5
RefChem:357342
CAS 86264-49-5C14H16N2O4
Spiro(imidazolidine-4,2'(1'H)-naphthalene)-2,5-dione, 3',4'-dihydro-1-methyl- chemical structure, C13H14N2O2, CAS 109402-15-5
Spiro(imidazolidine-4,2'(1'H)-naphthalene)-2,5-dione, 3',4'-dihydro-1-methyl-
CAS 109402-15-5C13H14N2O2
Spiro(imidazolidine-4,2'(1'H)-naphthalene)-2,5-dione, 3',4'-dihydro-1-(2-hydroxyethyl)- chemical structure, C14H16N2O3, CAS 111526-26-2
Spiro(imidazolidine-4,2'(1'H)-naphthalene)-2,5-dione, 3',4'-dihydro-1-(2-hydroxyethyl)-
CAS 111526-26-2C14H16N2O3
beta-Tethymustine chemical structure, C18H23Cl2N3O2, CAS 198416-57-8
beta-Tethymustine
CAS 198416-57-8C18H23Cl2N3O2
3',4'-Dihydro-8'-methoxyspiro[imidazolidine-4,2'(1'H)-naphthalene]-2,5-dione chemical structure, C13H14N2O3, CAS 67544-72-3
3',4'-Dihydro-8'-methoxyspiro[imidazolidine-4,2'(1'H)-naphthalene]-2,5-dione
CAS 67544-72-3C13H14N2O3
6'-Amino-3',4'-dihydrospiro[imidazolidine-4,2'(1'H)-naphthalene]-2,5-dione chemical structure, C12H13N3O2, CAS 765941-57-9
6'-Amino-3',4'-dihydrospiro[imidazolidine-4,2'(1'H)-naphthalene]-2,5-dione
CAS 765941-57-9C12H13N3O2
6'-Bromospiro[imidazolidine-5,2'-tetralin]-2,4-dione chemical structure, C12H11BrN2O2, CAS 659736-46-6
6'-Bromospiro[imidazolidine-5,2'-tetralin]-2,4-dione
CAS 659736-46-6C12H11BrN2O2
1-(Prop-2-en-1-yl)-3',4'-dihydro-1'H-spiro[imidazolidine-4,2'-naphthalene]-2,5-dione chemical structure, C15H16N2O2, CAS 279247-21-1
1-(Prop-2-en-1-yl)-3',4'-dihydro-1'H-spiro[imidazolidine-4,2'-naphthalene]-2,5-dione
CAS 279247-21-1C15H16N2O2
3',4'-Dihydro-2,5-dioxospiro(imidazolidine-4,2'(1'H)-naphthalene)-1-acetic acid chemical structure, C14H14N2O4, CAS 843-61-8
3',4'-Dihydro-2,5-dioxospiro(imidazolidine-4,2'(1'H)-naphthalene)-1-acetic acid
CAS 843-61-8C14H14N2O4
(S)-5',8'-Dimethoxy-3',4'-dihydro-1'H-spiro[imidazolidine-4,2'-naphthalene]-2,5-dione chemical structure, C14H16N2O4, CAS 1391557-65-5
(S)-5',8'-Dimethoxy-3',4'-dihydro-1'H-spiro[imidazolidine-4,2'-naphthalene]-2,5-dione
CAS 1391557-65-5C14H16N2O4
6'-Chloro-3',4'-dihydro-1'H-spiro[imidazolidine-4,2'-naphthalene]-2,5-dione chemical structure, C12H11ClN2O2, CAS 74444-82-9
6'-Chloro-3',4'-dihydro-1'H-spiro[imidazolidine-4,2'-naphthalene]-2,5-dione
CAS 74444-82-9C12H11ClN2O2