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Murcko scaffold

Ring system with 3 rings and 14 atoms

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
6
With full pages
1
Scaffold SMILES

c1ccc2c(c1)CCC1(CCOC1)O2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc2c(c1)CCC1(CCOC1)O2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

3,4-Dihydrospiro[1-benzopyran-2,3'-oxolan]-4-amine chemical structure, C12H15NO2, CAS 1598898-13-5
3,4-Dihydrospiro[1-benzopyran-2,3'-oxolan]-4-amine
CAS 1598898-13-5C12H15NO2
3,4-Dihydrospiro[1-benzopyran-2,3'-oxolane]-4-amine hydrochloride chemical structure, C12H16ClNO2, CAS 2172508-70-0
3,4-Dihydrospiro[1-benzopyran-2,3'-oxolane]-4-amine hydrochloride
CAS 2172508-70-0C12H16ClNO2
N-Spiro[3,4-dihydrochromene-2,3'-oxolane]-4-ylprop-2-enamide chemical structure, C15H17NO3, CAS 2361658-25-3
N-Spiro[3,4-dihydrochromene-2,3'-oxolane]-4-ylprop-2-enamide
CAS 2361658-25-3C15H17NO3
(E)-4-(Dimethylamino)-N-spiro[3,4-dihydrochromene-2,3'-oxolane]-4-ylbut-2-enamide chemical structure, C18H24N2O3, CAS 2411325-55-6
(E)-4-(Dimethylamino)-N-spiro[3,4-dihydrochromene-2,3'-oxolane]-4-ylbut-2-enamide
CAS 2411325-55-6C18H24N2O3
2-Chloro-N-spiro[3,4-dihydrochromene-2,3'-oxolane]-4-ylacetamide chemical structure, C14H16ClNO3, CAS 2411255-40-6
2-Chloro-N-spiro[3,4-dihydrochromene-2,3'-oxolane]-4-ylacetamide
CAS 2411255-40-6C14H16ClNO3
N-{3,4-Dihydrospiro[1-benzopyran-2,3'-oxolan]-4-yl}but-2-ynamide chemical structure, C16H17NO3, CAS 2411240-22-5
N-{3,4-Dihydrospiro[1-benzopyran-2,3'-oxolan]-4-yl}but-2-ynamide
CAS 2411240-22-5C16H17NO3