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Murcko scaffold

Ring system with 3 rings and 14 atoms

30 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
30
With full pages
3
Scaffold SMILES

c1ccc2c(c1)CCC1(CCCC1)O2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc2c(c1)CCC1(CCCC1)O2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

[(6-Ethoxy-3,4-dihydrospiro[[1]benzopyran-2,1'-cyclopentan]-4-yl)sulfanyl]acetic acid chemical structure, C17H22O4S, CAS 899710-27-1
[(6-Ethoxy-3,4-dihydrospiro[[1]benzopyran-2,1'-cyclopentan]-4-yl)sulfanyl]acetic acid
CAS 899710-27-1C17H22O4S
3,4-Dihydrospiro[1-benzopyran-2,1'-cyclopentan]-4-ol chemical structure, C13H16O2, CAS 70496-43-4
3,4-Dihydrospiro[1-benzopyran-2,1'-cyclopentan]-4-ol
CAS 70496-43-4C13H16O2
6-Ethoxy-3,4-dihydrospiro[chromene-2,1'-cyclopentan]-4-ol chemical structure, C15H20O3, CAS 1119450-08-6
6-Ethoxy-3,4-dihydrospiro[chromene-2,1'-cyclopentan]-4-ol
CAS 1119450-08-6C15H20O3
N-Methyl-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentan]-4-amine chemical structure, C14H19NO, CAS 1495575-03-5
N-Methyl-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentan]-4-amine
CAS 1495575-03-5C14H19NO
3,4-Dihydrospiro[1-benzopyran-2,1'-cyclopentane]-4-amine chemical structure, C13H17NO, CAS 70505-77-0
3,4-Dihydrospiro[1-benzopyran-2,1'-cyclopentane]-4-amine
CAS 70505-77-0C13H17NO
5,7-Dimethyl-3,4-dihydrospiro[[1]benzopyran-2,1'-cyclopentan]-4-amine chemical structure, C15H21NO, CAS 1017399-26-6
5,7-Dimethyl-3,4-dihydrospiro[[1]benzopyran-2,1'-cyclopentan]-4-amine
CAS 1017399-26-6C15H21NO
6,8-Dichloro-3,4-dihydrospiro[[1]benzopyran-2,1'-cyclopentan]-4-amine chemical structure, C13H15Cl2NO, CAS 1017399-30-2
6,8-Dichloro-3,4-dihydrospiro[[1]benzopyran-2,1'-cyclopentan]-4-amine
CAS 1017399-30-2C13H15Cl2NO
(4R)-3,4-Dihydrospiro[1-benzopyran-2,1'-cyclopentan]-4-amine chemical structure, C13H17NO, CAS 1444803-38-6
(4R)-3,4-Dihydrospiro[1-benzopyran-2,1'-cyclopentan]-4-amine
CAS 1444803-38-6C13H17NO
(4R)-6-Chloro-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentan]-4-amine chemical structure, C13H16ClNO, CAS 1604409-93-9
(4R)-6-Chloro-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentan]-4-amine
CAS 1604409-93-9C13H16ClNO
(4S)-6-Chloro-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentane]-4-amine chemical structure, C13H16ClNO, CAS 1604418-66-7
(4S)-6-Chloro-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentane]-4-amine
CAS 1604418-66-7C13H16ClNO
Ethyl 3,4-dihydrospiro[[1]benzopyran-2,1'-cyclopentan]-4-ylcarbamate chemical structure, C16H21NO3, CAS 1000356-56-8
Ethyl 3,4-dihydrospiro[[1]benzopyran-2,1'-cyclopentan]-4-ylcarbamate
CAS 1000356-56-8C16H21NO3
3-[(6-Ethoxy-3,4-dihydrospiro[chromene-2,1'-cyclopentan]-4-yl)thio]propanoic acid chemical structure, C18H24O4S, CAS 1171515-79-9
3-[(6-Ethoxy-3,4-dihydrospiro[chromene-2,1'-cyclopentan]-4-yl)thio]propanoic acid
CAS 1171515-79-9C18H24O4S
3,4-Dihydrospiro[chromene-2,1'-cyclopentan]-4-amine hydrochloride chemical structure, C13H18ClNO, CAS 1609395-35-8
3,4-Dihydrospiro[chromene-2,1'-cyclopentan]-4-amine hydrochloride
CAS 1609395-35-8C13H18ClNO
(4R)-6-Fluoro-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentan]-4-amine chemical structure, C13H16FNO, CAS 1604369-88-1
(4R)-6-Fluoro-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentan]-4-amine
CAS 1604369-88-1C13H16FNO
(4S)-6-Fluoro-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentan]-4-amine chemical structure, C13H16FNO, CAS 939411-27-5
(4S)-6-Fluoro-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentan]-4-amine
CAS 939411-27-5C13H16FNO
(4S)-6-Fluoro-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentane]-4-ol chemical structure, C13H15FO2, CAS 1604253-29-3
(4S)-6-Fluoro-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentane]-4-ol
CAS 1604253-29-3C13H15FO2
(4R)-6-Fluoro-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentane]-4-ol chemical structure, C13H15FO2, CAS 939411-25-3
(4R)-6-Fluoro-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentane]-4-ol
CAS 939411-25-3C13H15FO2
(4S)-3,4-Dihydrospiro[1-benzopyran-2,1'-cyclopentan]-4-ol chemical structure, C13H16O2, CAS 171200-73-0
(4S)-3,4-Dihydrospiro[1-benzopyran-2,1'-cyclopentan]-4-ol
CAS 171200-73-0C13H16O2
(4R)-3,4-Dihydrospiro[1-benzopyran-2,1'-cyclopentan]-4-ol chemical structure, C13H16O2, CAS 1604445-28-4
(4R)-3,4-Dihydrospiro[1-benzopyran-2,1'-cyclopentan]-4-ol
CAS 1604445-28-4C13H16O2
3,4-Dihydrospiro[1-benzopyran-2,1'-cyclopentan]-5-ol chemical structure, C13H16O2, CAS 2097966-98-6
3,4-Dihydrospiro[1-benzopyran-2,1'-cyclopentan]-5-ol
CAS 2097966-98-6C13H16O2
(4S)-6-Chloro-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentane]-4-amine hydrochloride chemical structure, C13H17Cl2NO, CAS 2219353-78-1
(4S)-6-Chloro-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentane]-4-amine hydrochloride
CAS 2219353-78-1C13H17Cl2NO
(4S)-6-Fluoro-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentane]-4-amine hydrochloride chemical structure, C13H17ClFNO, CAS 2219353-63-4
(4S)-6-Fluoro-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentane]-4-amine hydrochloride
CAS 2219353-63-4C13H17ClFNO
(4R)-4-Azido-6-fluoro-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentane] chemical structure, C13H14FN3O, CAS 2225126-91-8
(4R)-4-Azido-6-fluoro-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentane]
CAS 2225126-91-8C13H14FN3O
(4R)-6-Fluoro-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentane]-4-amine hydrochloride chemical structure, C13H17ClFNO, CAS 2225126-79-2
(4R)-6-Fluoro-3,4-dihydrospiro[1-benzopyran-2,1'-cyclopentane]-4-amine hydrochloride
CAS 2225126-79-2C13H17ClFNO