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Murcko scaffold

Ring system with 3 rings and 17 atoms

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
21
With full pages
5
Scaffold SMILES

O=C(Nc1nc(-c2ccccc2)cs1)C1CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1nc(-c2ccccc2)cs1)C1CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

N-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide chemical structure, C14H14N2O2S, CAS 330189-59-8
N-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide
CAS 330189-59-8C14H14N2O2S
N-[4-(3,4-Dichlorophenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide chemical structure, C13H10Cl2N2OS, CAS 330189-62-3
N-[4-(3,4-Dichlorophenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide
CAS 330189-62-3C13H10Cl2N2OS
N-[4-(4-Methylphenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide chemical structure, C14H14N2OS, CAS 333397-48-1
N-[4-(4-Methylphenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide
CAS 333397-48-1C14H14N2OS
N-[4-(2,4-Dimethylphenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide chemical structure, C15H16N2OS, CAS 352678-67-2
N-[4-(2,4-Dimethylphenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide
CAS 352678-67-2C15H16N2OS
N-[4-(4-Nitrophenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide chemical structure, C13H11N3O3S, CAS 354140-14-0
N-[4-(4-Nitrophenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide
CAS 354140-14-0C13H11N3O3S
N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide chemical structure, C13H11ClN2OS, CAS 406194-67-0
N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide
CAS 406194-67-0C13H11ClN2OS
N-[4-(4-Propan-2-ylphenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide chemical structure, C16H18N2OS, CAS 476278-65-6
N-[4-(4-Propan-2-ylphenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide
CAS 476278-65-6C16H18N2OS
N-[4-(4-tert-Butylphenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide chemical structure, C17H20N2OS, CAS 392238-47-0
N-[4-(4-tert-Butylphenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide
CAS 392238-47-0C17H20N2OS
Ethyl 2-(cyclopropanecarbonylamino)-4-phenyl-1,3-thiazole-5-carboxylate chemical structure, C16H16N2O3S, CAS 392238-48-1
Ethyl 2-(cyclopropanecarbonylamino)-4-phenyl-1,3-thiazole-5-carboxylate
CAS 392238-48-1C16H16N2O3S
N-[4-(4-Cyanophenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide chemical structure, C14H11N3OS, CAS 476278-67-8
N-[4-(4-Cyanophenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide
CAS 476278-67-8C14H11N3OS
N-[4-(2,5-Dimethoxyphenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide chemical structure, C15H16N2O3S, CAS 484654-87-7
N-[4-(2,5-Dimethoxyphenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide
CAS 484654-87-7C15H16N2O3S
N-[4-(4-Bromophenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide chemical structure, C13H11BrN2OS, CAS 313405-50-4
N-[4-(4-Bromophenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide
CAS 313405-50-4C13H11BrN2OS
N-[4-(4-Ethoxyphenyl)-5-methyl-1,3-thiazol-2-yl]cyclopropanecarboxamide chemical structure, C16H18N2O2S, CAS 536733-03-6
N-[4-(4-Ethoxyphenyl)-5-methyl-1,3-thiazol-2-yl]cyclopropanecarboxamide
CAS 536733-03-6C16H18N2O2S
N-[4-(4-Methoxyphenyl)-5-methyl-1,3-thiazol-2-yl]cyclopropanecarboxamide chemical structure, C15H16N2O2S, CAS 536734-11-9
N-[4-(4-Methoxyphenyl)-5-methyl-1,3-thiazol-2-yl]cyclopropanecarboxamide
CAS 536734-11-9C15H16N2O2S
N-[4-(4-Iodophenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide chemical structure, C13H11IN2OS, CAS 313406-01-8
N-[4-(4-Iodophenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide
CAS 313406-01-8C13H11IN2OS
2,2-Dichloro-N-[4-(2,4-dichlorophenyl)-1,3-thiazol-2-yl]-1-methylcyclopropanecarboxamide chemical structure, C14H10Cl4N2OS, CAS 444937-29-5
2,2-Dichloro-N-[4-(2,4-dichlorophenyl)-1,3-thiazol-2-yl]-1-methylcyclopropanecarboxamide
CAS 444937-29-5C14H10Cl4N2OS
N-[4-(3-Nitrophenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide chemical structure, C13H11N3O3S, CAS 330189-58-7
N-[4-(3-Nitrophenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide
CAS 330189-58-7C13H11N3O3S
N-[4-(3-Methoxyphenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide chemical structure, C14H14N2O2S, CAS 536731-87-0
N-[4-(3-Methoxyphenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide
CAS 536731-87-0C14H14N2O2S
2,2-Dibromo-1-methyl-N-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide chemical structure, C14H11Br2N3O3S, CAS 444925-72-8
2,2-Dibromo-1-methyl-N-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide
CAS 444925-72-8C14H11Br2N3O3S
AK-968/40733741 chemical structure, C14H11Cl3N2OS, CAS 496017-29-9
AK-968/40733741
CAS 496017-29-9C14H11Cl3N2OS
N-[4-(3-Bromophenyl)(1,3-thiazol-2-yl)]cyclopropylcarboxamide chemical structure, C13H11BrN2OS, CAS 905767-33-1
N-[4-(3-Bromophenyl)(1,3-thiazol-2-yl)]cyclopropylcarboxamide
CAS 905767-33-1C13H11BrN2OS