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Murcko scaffold

5-[1-(Benzenesulfonyl)-3-pyrazolyl]-2-phenylthiazole scaffold

4 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
4
With full pages
3
Scaffold SMILES

O=S(=O)(c1ccccc1)n1ccc(-c2cnc(-c3ccccc3)s2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-[1-(Benzenesulfonyl)-3-pyrazolyl]-2-phenylthiazole page
Murcko scaffold O=S(=O)(c1ccccc1)n1ccc(-c2cnc(-c3ccccc3)s2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

5-(1-((4-Methoxyphenyl)sulfonyl)-1H-pyrazol-3-yl)-2-phenyl-1,3-thiazole chemical structure, C19H15N3O3S2, CAS 318248-78-1
5-(1-((4-Methoxyphenyl)sulfonyl)-1H-pyrazol-3-yl)-2-phenyl-1,3-thiazole
CAS 318248-78-1C19H15N3O3S2
5-[1-(Benzenesulfonyl)-3-pyrazolyl]-2-phenylthiazole chemical structure, C18H13N3O2S2, CAS 318248-80-5
5-[1-(Benzenesulfonyl)-3-pyrazolyl]-2-phenylthiazole
CAS 318248-80-5C18H13N3O2S2
5-(1-((4-Chlorophenyl)sulfonyl)-1H-pyrazol-3-yl)-2-phenyl-1,3-thiazole chemical structure, C18H12ClN3O2S2, CAS 318255-91-3
5-(1-((4-Chlorophenyl)sulfonyl)-1H-pyrazol-3-yl)-2-phenyl-1,3-thiazole
CAS 318255-91-3C18H12ClN3O2S2
5-[1-(4-Fluorophenyl)sulfonyl-3-pyrazolyl]-2-phenylthiazole chemical structure, C18H12FN3O2S2, CAS 318255-93-5
5-[1-(4-Fluorophenyl)sulfonyl-3-pyrazolyl]-2-phenylthiazole
CAS 318255-93-5C18H12FN3O2S2