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2,2'-Bipyridine chemical structure, C10H8N2, CAS 366-18-7
2D chemical structure

Key facts

What buyers check first

Appearance
White crystals
Melting point
72 ยฐC
Boiling point
273.5 ยฐC
Solubility
In water, 5.93 ร— 10โบยณ mg/l @ 25 ยฐC
HS code
293339
Category
Builders and chelating agents
Illustrative photo, colourless crystals in a clear glass bottle on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is 2,2'-Bipyridine?

Plain description, key identifiers and synonyms

2,2'-bipyridine is a bipyridine in which the two pyridine moieties are linked by a bond between positions C-2 and C-2'. It has a role as a ferroptosis inhibitor and a chelator.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-pyridin-2-ylpyridine
CAS number
366-18-7 CAS number cross-checked
EC number
206-674-4
Molecular formula
C10H8N2
UNII
551W113ZEP
MDL number
MFCD00006212
InChIKey
ROFVEXUMMXZLPA-UHFFFAOYSA-N
InChI
InChI=1S/C10H8N2/c1-3-7-11-9(5-1)10-6-2-4-8-12-10/h1-8H
SMILES (canonical and isomeric)
C1=CC=NC(=C1)C2=CC=CC=N2

Synonyms

  • 2,2'-Dipyridyl
  • 2,2'-Bipyridyl
  • Bipyridine
  • 2,2'-Dipyridine
  • 2-(2-Pyridyl)pyridine
  • 2,2'-Bipyridin
  • 2,2-bipyridyl
  • alpha,alpha'-Dipyridyl
  • alpha,alpha'-Bipyridyl
  • alpha,alpha'-Dipyridine
  • 2-pyridin-2-ylpyridine
  • 2,2-Bipyridine
  • 2,2 Bipyridyl
  • 2,2-Dipyridyl
  • 2,2' Bipyridine
  • alpha,alpha'-Bipyridine
  • 2,2 Bipyridine
  • 2,2 Dipyridyl
  • 2,2' Dipyridyl
  • Dipyridyl, 2,2
  • alpha,alpha Dipyridyl
  • alpha,alpha-Dipyridyl
  • Dipyridyl, 2,2'
  • Bipyridyl
  • AA-DP
Show all 34 synonyms
  • dipyridyl
  • 2-(pyridin-2-yl)pyridine
  • [2,2']Bipyridinyl
  • BPY
  • CI 588
  • 2,2 inverted exclamation mark(R)-Bipyridine
  • pyridine, 2-(2-pyridyl)-
  • [2,2]bipyridinyl
  • Bipy

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
White crystalsexp.
Melting point
72 ยฐCexp.
Boiling point
273.5 ยฐCexp.
Solubility
In water, 5.93 ร— 10โบยณ mg/l @ 25 ยฐCexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
156.19 g/molcalc.
Exact mass
156.0687 Dacalc.
LogP (octanol/water)
2.14calc.
Topological polar surface area
25.78 ร…ยฒcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
1calc.
Heavy atoms
12calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(-c2ccccn2)nc1

c1ccc(-c2ccccn2)nc1

2 rings, 12 atoms. This chemical is the scaffold itself.

892 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H301 + H311Toxic if swallowed. Toxic in contact with skin.
  • H301Toxic if swallowed.
  • H311Toxic in contact with skin.
  • H312Harmful in contact with skin.
  • H319Causes serious eye irritation.
  • H412Harmful to aquatic life with long lasting effects.
Precautionary statements (18)
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P316Get emergency medical help immediately.
  • P317Get medical help.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P337 + P317If eye irritation persists: Get medical help.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

2,2'-Bipyridine suppliers

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2,2'-Bipyridine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Iron chelating agent.

Indicator for photometric determination of Ag, Cd, Cu, Fe, and Mo.

Important chemical intermediate in the production of the herbicide diquat, the quaternary salt is used as a contact herbicide.

Pharmacological actions

  • Chelating Agents
  • Indicators and Reagents

Roles

  • chelator
  • ferroptosis inhibitor
  • ligand

How it is made

Dehydrogenation of pyridine with nickel or other metal catalysts gives 2,2'-bipyridyl.

Raney nickel reduction (of pyridine) gives 2,2'-bipyridine.

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 2,2'-Bipyridine is traded under.

HS 2933.39Indicative HS code

Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structureโ€ฆ

World exports in 2024
$9.16B
โˆ’17.9% vs 2023, imports $10.6B
2019 to 2024
Top exporters
  1. China21.5%
  2. India * partner reported12.3%
  3. Ireland11.6%
Top importers
  1. Germany14.2%
  2. United States12.8%
  3. Brazil10.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for 2,2'-Bipyridine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 2,2'-Bipyridine, based on the data on this page

What is 2,2'-Bipyridine?

2,2'-bipyridine is a bipyridine in which the two pyridine moieties are linked by a bond between positions C-2 and C-2'. It has a role as a ferroptosis inhibitor and a chelator.

What is the CAS number of 2,2'-Bipyridine?

The CAS registry number of 2,2'-Bipyridine is 366-18-7.

What is the molecular formula and weight of 2,2'-Bipyridine?

The molecular formula of 2,2'-Bipyridine is C10H8N2 and its molar mass is 156.19 g/mol.

What is 2,2'-Bipyridine used for?

Iron chelating agent. Indicator for photometric determination of Ag, Cd, Cu, Fe, and Mo. Important chemical intermediate in the production of the herbicide diquat, the quaternary salt is used as a contact herbicide.

Is 2,2'-Bipyridine hazardous?

2,2'-Bipyridine carries the GHS signal word "Danger". Main hazards: toxic if swallowed. toxic in contact with skin, toxic if swallowed, toxic in contact with skin. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of 2,2'-Bipyridine?

2,2'-Bipyridine is usually classified under HS code 293339 (Compounds containing an unfused pyridine ring (whether or not hydrogenated) in theโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy 2,2'-Bipyridine?

CompoundList lists 132 suppliers of 2,2'-Bipyridine in China, United States, United Kingdom, India and 13 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy 2,2'-Bipyridine in India?

5 suppliers in India list 2,2'-Bipyridine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of 2,2'-Bipyridine?

Suppliers quote 2,2'-Bipyridine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle 2,2'-Bipyridine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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