2,3-Dichlorophenol
Also known as Phenol, 2,3-dichloro-, Dichlorophenol, Phenol, 2,3-dichloro-, 2,3-Dichlorophenol, NSC 60646
Key facts
What buyers check first
- Appearance
- Crystals from ligroin and benzene
- Melting point
- 58 °C
- Boiling point
- 206 °C
- Solubility
- In water, 3,600 mg/L at 25 °C
- HS code
- 290819
- Category
- Impurities and reference standards
- UN number
- UN 2020

What is 2,3-Dichlorophenol?
Plain description, key identifiers and synonyms
2,3-dichlorophenol appears as brown crystals (from ligroin, benzene). Taste threshold concentration 0.00004 mg/L. Odor threshold concentration 0.03 mg/L. (NTP, 1992)
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 2,3-dichlorophenol
- CAS number
- 576-24-9 CAS number cross-checkedOther or deprecated CAS: 25167-81-1
- EC numbers
- 209-399-8, 246-693-5
- Molecular formula
- C6H4Cl2O
- UNII
- IZM39U444L
- MDL number
- MFCD00002160
- InChIKey
- UMPSXRYVXUPCOS-UHFFFAOYSA-N
- InChI
- InChI=1S/C6H4Cl2O/c7-4-2-1-3-5(9)6(4)8/h1-3,9H
- SMILES (canonical and isomeric)
- C1=CC(=C(C(=C1)Cl)Cl)O
Synonyms
- Phenol, 2,3-dichloro-
- Dichlorophenol
- Phenol, 2,3-dichloro-, 2,3-Dichlorophenol, NSC 60646
- 2,3 dichlorophenol
- Phenol,3-dichloro-
- 2,3-dichloro phenol
- Ketoconazole Impurity 50
- 2,3-Dichlorophenol, 98%
- 4-06-00-00883 (Beilstein Handbook Reference)
- Dichlorophenol, 2,3-
- 2,3-Dichlorophenol, analytical standard
- 2,3-Dichlorophenol 10 microg/mL in Methanol
- 2,3-Dichlorophenol Solution in Methanol, 100_g/mL
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | Crystals from ligroin and benzeneexp.Measured value |
|---|---|
| Taste | Taste Threshold in water: 0.04 ug/l.exp.Measured value |
| Melting point | 58 °Cexp.Measured value |
| Boiling point | 206 °Cexp.Measured value |
| Solubility | In water, 3,600 mg/L at 25 °Cexp.Measured value |
| Vapour pressure | 0.058 mm Hg at 25 °Cexp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 163.00 g/molcalc.Computed value |
|---|---|
| Exact mass | 161.9639 Dacalc.Computed value |
| LogP (octanol/water) | 2.7calc.Computed value |
| Topological polar surface area | 20.23 Ųcalc.Computed value |
| Hydrogen bond donors | 1calc.Computed value |
| Hydrogen bond acceptors | 1calc.Computed value |
| Rotatable bonds | 0calc.Computed value |
| Heavy atoms | 9calc.Computed value |
| Rings | 1calc.Computed value |
| Aromatic rings | 1calc.Computed value |
| Fraction sp3 carbons | 0calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H302Harmful if swallowed.
- H312Harmful in contact with skin.
- H315Causes skin irritation.
- H319Causes serious eye irritation.
- H411Toxic to aquatic life with long lasting effects.
Precautionary statements (16)
- P264Wash skin thoroughly after handling.
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P270Do not eat, drink or smoke when using this product.
- P273Avoid release to the environment.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P301 + P317If swallowed: Get medical help.
- P302 + P352If on skin: Wash with plenty of water.
- P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P317Get medical help.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P330Rinse mouth.
- P332 + P317If skin irritation occurs: Get medical help.
- P337 + P317If eye irritation persists: Get medical help.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P391Collect spillage.
- P501Dispose of contents and container in accordance with local regulations.
- UN number
- UN 2020
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aid2,3-Dichlorophenol suppliers
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2,3-Dichlorophenol price
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Uses and applications
What the substance is used for, by industry and function
Research chemical.
How it is made
Hydrolysis of chlorobenzenes can be carried out in alkaline aqueous media, with or without the presence of copper salts. It can be done in the vapor phase at 250-400 °C on phosphates or on silica at 500-550 °C. Hydrolysis is most frequently carried out in the presence of methanolic sodium or potassium at 150-200 °C and 1.0-3.0 MPa. (Mono-, Di-, and Trichlorophenols with Chlorine in a Meta Position)
Sulfonation of chlorobenzenes followed by the desulfonation of chlorobenzenesulfonic acids can be used to produce numerous chlorophenols.
Read more
The chlorobenzenes are sulfonated by using 15 - 20% oleum at 60 - 80 °C. The subsequent desulfonation is usually carried out by using 15 - 25% aqueous sodium hydroxide solution at 180 - 220 °C and 1.5 - 3.0 MPa. (Mono-, Di-, and Trichlorophenols with Chlorine in a Meta Position)
Sandmeyer Reaction. m-Chlorophenols can also be made by diazotization of the corresponding chloroanilines that have been obtained either by nitration of chlorobenzenes followed by hydrogenation or by chlorination of nitrobenzenes. (m-Chlorophenols)
Regulatory status
Inventories, regulations and trade controls that list this substance
United States
- TSCA inventory (USA)Status: Inactive in US commerce, Regulatory flags: Section 4 test rule or order
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code 2,3-Dichlorophenol is traded under.
Derivatives containing only halogen substituents and their salts, other
- China58.6%
- South Korea10.3%
- United States5.5%
* Partner reported figures, a lower bound.
The HS code shown for 2,3-Dichlorophenol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about 2,3-Dichlorophenol, based on the data on this page
What is 2,3-Dichlorophenol?
What is the CAS number of 2,3-Dichlorophenol?
What is the molecular formula and weight of 2,3-Dichlorophenol?
What is 2,3-Dichlorophenol used for?
Is 2,3-Dichlorophenol hazardous?
What is the HS code of 2,3-Dichlorophenol?
Where can I buy 2,3-Dichlorophenol?
Where can I buy 2,3-Dichlorophenol in India?
What is the price of 2,3-Dichlorophenol?
Guides for buyers
Practical guides that help when you source, ship or handle 2,3-Dichlorophenol
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, Trade and logisticsShipping dangerous goods: UN numbers, classes and packing groupsHow the UN dangerous goods system works for chemicals, from the nine classes and UN numbers to packing groups, UN packaging marks, labels, documents and segregation.Read
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