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Skin conditioning agents and actives

2-O-Ethyl ascorbic acid

Also known as L-Ascorbic acid, 2-O-Ethyl-, Vitamin C Facial Serum, (R)-5-((S)-1,2-Dihydroxyethyl)-3-ethoxy-4-hydroxyfuran-2(5H)-one

CAS 112894-37-8Formula C8H12O6Molar mass 204.18 g/mol
Drug substance
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2-O-Ethyl ascorbic acid chemical structure, C8H12O6, CAS 112894-37-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
112894-37-8
Formula
C8H12O6
Molar mass
204.18 g/mol
HS code
293220
Category
Skin conditioning agents and actives

What is 2-O-Ethyl ascorbic acid?

Plain description, key identifiers and synonyms

3-o-Ethyl-L-ascorbic acid is a butenolide.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2R)-2-[(1S)-1,2-dihydroxyethyl]-4-ethoxy-3-hydroxy-2H-furan-5-one
CAS number
112894-37-8 CAS number cross-checked
Molecular formula
C8H12O6
UNII
801M14RK9K
INCI name
2-O-ETHYL ASCORBIC ACID
InChIKey
GXRFOOHMMLYYNW-UJURSFKZSA-N
InChI
InChI=1S/C8H12O6/c1-2-13-7-5(11)6(4(10)3-9)14-8(7)12/h4,6,9-11H,2-3H2,1H3/t4-,6+/m0/s1
Canonical SMILES
CCOC1=C(O)C(C(O)CO)OC1=O
Isomeric SMILES
CCOC1=C([C@H](OC1=O)[C@H](CO)O)O

Synonyms

  • L-Ascorbic acid, 2-O-Ethyl-
  • Vitamin C Facial Serum
  • (R)-5-((S)-1,2-Dihydroxyethyl)-3-ethoxy-4-hydroxyfuran-2(5H)-one
  • (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-ethoxy-3-hydroxy-2H-furan-5-one
  • 2-o-Ethyl-l-ascorbic acid
  • (5R)-5-[(1S)-1,2-dihydroxyethyl]-3-ethoxy-4-hydroxy-2,5-dihydrofuran-2-one
  • L-ascorbic acid ethyl ester
  • (5R)-5-[(1S)-1,2-Dihydroxyethyl]-3-ethoxy-4-hydroxyfuran-2(5H)-one

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
204.18 g/molcalc.
Exact mass
204.0634 Dacalc.
LogP (octanol/water)
-0.93calc.
Topological polar surface area
96.22 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
4calc.
Heavy atoms
14calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.63calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=CCO1

O=C1C=CCO1

1 ring, 6 atoms, the 2(5H)-Furanone ring system.

877 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

2-O-Ethyl ascorbic acid suppliers

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2-O-Ethyl ascorbic acid price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name 2-O-ETHYL ASCORBIC ACID(skin conditioning)

Functional uses

  • Softener and conditioner

Cosmetic functions

  • Skin conditioning

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory
  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 2-O-Ethyl ascorbic acid is traded under.

HS 2932.20Indicative HS code

Lactones

World exports in 2024
$1.97B
−4.7% vs 2023, imports $2.07B
2019 to 2024
Top exporters
  1. China56.3%
  2. India * partner reported7.4%
  3. Germany7.3%
Top importers
  1. United States14.2%
  2. India * partner reported13.5%
  3. Brazil8.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for 2-O-Ethyl ascorbic acid is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 2-O-Ethyl ascorbic acid, based on the data on this page

What is 2-O-Ethyl ascorbic acid?

3-o-Ethyl-L-ascorbic acid is a butenolide.

What is the CAS number of 2-O-Ethyl ascorbic acid?

The CAS registry number of 2-O-Ethyl ascorbic acid is 112894-37-8.

What is the molecular formula and weight of 2-O-Ethyl ascorbic acid?

The molecular formula of 2-O-Ethyl ascorbic acid is C8H12O6 and its molar mass is 204.18 g/mol.

What is 2-O-Ethyl ascorbic acid used for?

Known uses and roles of 2-O-Ethyl ascorbic acid include skin conditioning agents in cosmetics and personal care, skin conditioning and softener and conditioner.

Is 2-O-Ethyl ascorbic acid hazardous?

No GHS hazard classification for 2-O-Ethyl ascorbic acid is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of 2-O-Ethyl ascorbic acid?

2-O-Ethyl ascorbic acid is usually classified under HS code 293220 (Lactones). This is indicative, confirm it with your customs broker before shipping.

Where can I buy 2-O-Ethyl ascorbic acid?

Post a free request on CompoundList and suppliers of 2-O-Ethyl ascorbic acid will send you quotes. Your contact details stay private until you accept a quote.

What is the price of 2-O-Ethyl ascorbic acid?

Suppliers quote 2-O-Ethyl ascorbic acid on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle 2-O-Ethyl ascorbic acid

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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