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Murcko scaffold

2(5H)-Furanone scaffold

878 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
878
With full pages
123
Scaffold SMILES

O=C1C=CCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 2(5H)-Furanone page
Murcko scaffold O=C1C=CCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 878 chemicals

2,5-Dihydro-5-oxo-2-furanacetic acid chemical structure, C6H6O4, CAS 6666-46-2
2,5-Dihydro-5-oxo-2-furanacetic acid
CAS 6666-46-2C6H6O4
2(5H)-Furanone chemical structure, C4H4O2, CAS 497-23-4
2(5H)-Furanone
CAS 497-23-4C4H4O2
4-Hydroxy-2-pentenoic acid gamma-lactone chemical structure, C5H6O2, CAS 591-11-7
4-Hydroxy-2-pentenoic acid gamma-lactone
CAS 591-11-7C5H6O2
5-Ethyl-2(5H)-furanone chemical structure, C6H8O2, CAS 2407-43-4
5-Ethyl-2(5H)-furanone
CAS 2407-43-4C6H8O2
5-Hydroxy-2,5-dihydrofuran-2-one chemical structure, C4H4O3, CAS 14032-66-7
5-Hydroxy-2,5-dihydrofuran-2-one
CAS 14032-66-7C4H4O3
Butenolide chemical structure, C6H7NO3, CAS 16275-44-8
Butenolide
CAS 16275-44-8C6H7NO3
5,5-Dimethyl-2(5H)-furanone chemical structure, C6H8O2, CAS 20019-64-1
5,5-Dimethyl-2(5H)-furanone
CAS 20019-64-1C6H8O2
3-Methyl-2(5H)-furanone chemical structure, C5H6O2, CAS 22122-36-7
3-Methyl-2(5H)-furanone
CAS 22122-36-7C5H6O2
3,4-Dichloro-5-methoxy-2(5H)-furanone chemical structure, C5H4Cl2O3, CAS 23066-93-5
3,4-Dichloro-5-methoxy-2(5H)-furanone
CAS 23066-93-5C5H4Cl2O3
3-Chloro-5-ethoxy-2(5H)-furanone chemical structure, C6H7ClO3, CAS 32830-75-4
3-Chloro-5-ethoxy-2(5H)-furanone
CAS 32830-75-4C6H7ClO3
3,5,5-Trimethyl-2(5H)-furanone chemical structure, C7H10O2, CAS 50598-50-0
3,5,5-Trimethyl-2(5H)-furanone
CAS 50598-50-0C7H10O2
3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone chemical structure, C5H3Cl3O3, CAS 77439-76-0
3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone
CAS 77439-76-0C5H3Cl3O3
3-Chloro-4-(dichloromethyl)-5-methoxy-2(5H)-furanone chemical structure, C6H5Cl3O3, CAS 97055-38-4
3-Chloro-4-(dichloromethyl)-5-methoxy-2(5H)-furanone
CAS 97055-38-4C6H5Cl3O3
2(5H)-Furanone, 3-chloro-5-((dimethylamino)methyl)-4,5-dimethyl- chemical structure, C9H14ClNO2, CAS 104502-43-4
2(5H)-Furanone, 3-chloro-5-((dimethylamino)methyl)-4,5-dimethyl-
CAS 104502-43-4C9H14ClNO2
2(5H)-Furanone, 3-bromo-5-((dimethylamino)methyl)-4,5-dimethyl- chemical structure, C9H14BrNO2, CAS 104502-47-8
2(5H)-Furanone, 3-bromo-5-((dimethylamino)methyl)-4,5-dimethyl-
CAS 104502-47-8C9H14BrNO2
2(5H)-Furanone, 3-bromo-5-((diethylamino)methyl)-4,5-dimethyl- chemical structure, C11H18BrNO2, CAS 106609-75-0
2(5H)-Furanone, 3-bromo-5-((diethylamino)methyl)-4,5-dimethyl-
CAS 106609-75-0C11H18BrNO2
2(5H)-Furanone, 3-chloro-5-((diethylamino)methyl)-4,5-dimethyl- chemical structure, C11H18ClNO2, CAS 106609-86-3
2(5H)-Furanone, 3-chloro-5-((diethylamino)methyl)-4,5-dimethyl-
CAS 106609-86-3C11H18ClNO2
3,4-Dichloro-5-(dichloromethyl)-5-hydroxy-2-furanone chemical structure, C5H2Cl4O3, CAS 108082-06-0
3,4-Dichloro-5-(dichloromethyl)-5-hydroxy-2-furanone
CAS 108082-06-0C5H2Cl4O3
3-Chloro-4-methyl-5-ethoxy-2(5H)-furanone chemical structure, C7H9ClO3, CAS 112309-60-1
3-Chloro-4-methyl-5-ethoxy-2(5H)-furanone
CAS 112309-60-1C7H9ClO3
3-Chloro-5-hydroxy-4-methyl-2(5H)-furanone chemical structure, C5H5ClO3, CAS 112309-61-2
3-Chloro-5-hydroxy-4-methyl-2(5H)-furanone
CAS 112309-61-2C5H5ClO3
5-Ethyl-3-hydroxy-4-methyl-2(5H)-furanone chemical structure, C7H10O3, CAS 698-10-2
5-Ethyl-3-hydroxy-4-methyl-2(5H)-furanone
CAS 698-10-2C7H10O3
Sotolone chemical structure, C6H8O3, CAS 28664-35-9
Sotolone
CAS 28664-35-9C6H8O3
3-Chloro-4-(dichloromethyl)-2(5H)-furanone chemical structure, C5H3Cl3O2, CAS 122551-89-7
3-Chloro-4-(dichloromethyl)-2(5H)-furanone
CAS 122551-89-7C5H3Cl3O2
5-Octyl-2(5H)-furanone chemical structure, C12H20O2, CAS 17756-68-2
5-Octyl-2(5H)-furanone
CAS 17756-68-2C12H20O2