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Aromatic building blocks

4-Hydroxyetretinate

Also known as Ro-11-4768, Ro 11-4768, ethyl (2E,4E,6E,8E)-9-(4-hydroxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate

CAS 66757-07-1Formula C22H28O3Molar mass 340.46 g/mol
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4-Hydroxyetretinate chemical structure, C22H28O3, CAS 66757-07-1
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
66757-07-1
Formula
C22H28O3
Molar mass
340.46 g/mol
HS code
291829
Category
Aromatic building blocks

What is 4-Hydroxyetretinate?

Plain description, key identifiers and synonyms

4-Hydroxyetretinate is a chemical substance with the molecular formula C22H28O3 and a molar mass of 340.46 g/mol. Its CAS registry number is 66757-07-1. The IUPAC name is ethyl (2E,4E,6E,8E)-9-(4-hydroxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
ethyl (2E,4E,6E,8E)-9-(4-hydroxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate
CAS number
66757-07-1
Molecular formula
C22H28O3
InChIKey
NIOLMQBHFHVZML-PAAZSCCJSA-N
InChI
InChI=1S/C22H28O3/c1-7-25-22(24)13-16(3)10-8-9-15(2)11-12-20-17(4)14-21(23)19(6)18(20)5/h8-14,23H,7H2,1-6H3/b10-8+,12-11+,15-9+,16-13+
Canonical SMILES
CCOC(=O)C=C(C)C=CC=C(C)C=Cc1c(C)cc(O)c(C)c1C
Isomeric SMILES
CCOC(=O)/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C(=C(C=C1C)O)C)C

Synonyms

  • Ro-11-4768
  • Ro 11-4768
  • ethyl (2E,4E,6E,8E)-9-(4-hydroxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate
  • 9-(4-Hydroxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid, ethyl ester
  • 2,4,6,8-Nonatetraenoic acid, 9-(4-hydroxy-2,3,6-trimethylphenyl-3,7-dimethyl-, ethyl ester, (all-E)-
  • 9-(4-Hydroxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid,ethyl ester

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
340.46 g/molcalc.
Exact mass
340.2038 Dacalc.
LogP (octanol/water)
5.34calc.
Topological polar surface area
46.53 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
6calc.
Heavy atoms
25calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.32calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

4-Hydroxyetretinate suppliers

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4-Hydroxyetretinate price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 4-Hydroxyetretinate is traded under.

HS 2918.29Indicative HS code

Carboxylic acids, (with phenol function but without other oxygen function), their anhydrides, halides…

World exports in 2024
$861M
+0.9% vs 2023, imports $892M
2019 to 2024
Top exporters
  1. China30.5%
  2. South Korea18.3%
  3. Switzerland * partner reported13.3%
Top importers
  1. United States14.7%
  2. Germany13.3%
  3. Japan10.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for 4-Hydroxyetretinate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 4-Hydroxyetretinate, based on the data on this page

What is 4-Hydroxyetretinate?

4-Hydroxyetretinate is a chemical substance with the molecular formula C22H28O3 and a molar mass of 340.46 g/mol. Its CAS registry number is 66757-07-1. The IUPAC name is ethyl (2E,4E,6E,8E)-9-(4-hydroxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate.

What is the CAS number of 4-Hydroxyetretinate?

The CAS registry number of 4-Hydroxyetretinate is 66757-07-1.

What is the molecular formula and weight of 4-Hydroxyetretinate?

The molecular formula of 4-Hydroxyetretinate is C22H28O3 and its molar mass is 340.46 g/mol.

What is 4-Hydroxyetretinate used for?

Known uses and roles of 4-Hydroxyetretinate include building blocks in research and laboratory.

Is 4-Hydroxyetretinate hazardous?

No GHS hazard classification for 4-Hydroxyetretinate is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of 4-Hydroxyetretinate?

4-Hydroxyetretinate is usually classified under HS code 291829 (Carboxylic acids with phenol function but without other oxygen function, their…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy 4-Hydroxyetretinate?

Post a free request on CompoundList and suppliers of 4-Hydroxyetretinate will send you quotes. Your contact details stay private until you accept a quote.

What is the price of 4-Hydroxyetretinate?

Suppliers quote 4-Hydroxyetretinate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle 4-Hydroxyetretinate

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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