CompoundList

5-Methoxytryptamine

Also known as 2-(5-Methoxy-1H-indol-3-yl)ethanamine, Methoxytryptamine, O-Methylserotonin

5-Methoxytryptamine chemical structure, C11H14N2O, CAS 608-07-1
2D chemical structure

Key facts

What buyers check first

CAS number
608-07-1
Formula
C11H14N2O
Molar mass
190.25 g/mol
EC number
210-153-7
HS code
293399
Category
Impurities and reference standards

What is 5-Methoxytryptamine?

Plain description, key identifiers and synonyms

5-methoxytryptamine is a member of the class of tryptamines that is the methyl ether derivative of serotonin. It has a role as a 5-hydroxytryptamine 2B receptor agonist, a 5-hydroxytryptamine 2C receptor agonist, a 5-hydroxytryptamine 2A receptor agonist, an antioxidant, a serotonergic agonist, a neuroprotective agent, a radiation protective agent, a mouse metabolite, a cardioprotective agent and a human metabolite. It is a member of tryptamines, an aromatic ether and a primary amino compound. It is functionally related to a serotonin. It is a conjugate base of a 5-methoxytryptamine(1+).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-(5-methoxy-1H-indol-3-yl)ethanamine
CAS number
608-07-1 CAS number cross-checked
EC number
210-153-7
Molecular formula
C11H14N2O
UNII
3VMW6141KC
MDL number
MFCD00005662
InChIKey
JTEJPPKMYBDEMY-UHFFFAOYSA-N
InChI
InChI=1S/C11H14N2O/c1-14-9-2-3-11-10(6-9)8(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3
SMILES (canonical and isomeric)
COC1=CC2=C(C=C1)NC=C2CCN

Synonyms

  • 2-(5-Methoxy-1H-indol-3-yl)ethanamine
  • Methoxytryptamine
  • O-Methylserotonin
  • 3-(2-Aminoethyl)-5-methoxyindole
  • 1H-Indole-3-ethanamine, 5-methoxy-
  • 5-Mot
  • 2-(5-Methoxy-1H-Indol-3-Yl)Ethan-1-Amine
  • 5-MeOT
  • 5-methoxy-1H-indole-3-ethanamine
  • 5 Methoxytryptamine
  • Meksamine
  • Mexamine
  • Mexamine base
  • Meksamin
  • 2-(5-Methoxyindol-3-yl)ethylamine
  • Meksamin (free base)
  • o-methyl serotonin
  • Indole, 3-(2-aminoethyl)-5-methoxy-
  • 5-Methoxytryptamine (5-MT)
  • 2-(5-Methoxy-1H-indol-3-yl)-ethylamine
  • Deacetylmelatonin
  • 2-(5-Methoxy-1H-indol-3-yl)ethanamine (5-Methoxytryptamine)
  • 2-(5-Methoxy-1H-indol-3-yl)ethanamine, 5-Methoxytryptamine, Melatonin Related Compound A (USP), Melatonin Related Compound A
  • 5-methoxy-tryptamine
  • 5-Methoxy tryptamine
Show all 33 synonyms
  • tryptamine, 5-Methoxy
  • 2-(5-Methoxy-1H-indol-3-yl)ethylamine
  • Tryptamine, 5-methoxy-
  • Biomol-NT_000156
  • 5-Methoxytryptamine, 97%
  • 5-22-12-00018 (Beilstein Handbook Reference)
  • Methoxytryptamine, 5-
  • 5-Methoxytryptamine, free base

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
190.25 g/molcalc.
Exact mass
190.1106 Dacalc.
LogP (octanol/water)
1.68calc.
Topological polar surface area
51.04 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
3calc.
Heavy atoms
14calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.27calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2[nH]ccc2c1

c1ccc2[nH]ccc2c1

2 rings, 9 atoms, the Indole ring system.

25,097 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

5-Methoxytryptamine suppliers

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5-Methoxytryptamine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • 5-hydroxytryptamine 2A receptor agonist
  • 5-hydroxytryptamine 2B receptor agonist
  • 5-hydroxytryptamine 2C receptor agonist
  • agonist
  • animal metabolite
  • antioxidant
  • cardioprotective agent
  • eukaryotic metabolite
  • human metabolite
  • mammalian metabolite
  • metabolite
  • mouse metabolite
  • neuroprotective agent
  • neurotransmitter agent
  • pharmaceutical
  • protective agent
  • radiation protective agent
  • serotonergic agonist
  • serotonergic drug

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 5-Methoxytryptamine is traded under.

HS 2933.99Indicative HS code

Heterocyclic compounds with nitrogen hetero-atom(s) only, other

World exports in 2024
$12.1B
−31.0% vs 2023, imports $28.8B
2019 to 2024
Top exporters
  1. China30.5%
  2. India * partner reported16.3%
  3. Ireland9.0%
Top importers
  1. Slovenia31.7%
  2. Italy24.2%
  3. United States5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for 5-Methoxytryptamine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 5-Methoxytryptamine, based on the data on this page

What is 5-Methoxytryptamine?

5-methoxytryptamine is a member of the class of tryptamines that is the methyl ether derivative of serotonin.

What is the CAS number of 5-Methoxytryptamine?

The CAS registry number of 5-Methoxytryptamine is 608-07-1.

What is the molecular formula and weight of 5-Methoxytryptamine?

The molecular formula of 5-Methoxytryptamine is C11H14N2O and its molar mass is 190.25 g/mol.

What is 5-Methoxytryptamine used for?

Known uses and roles of 5-Methoxytryptamine include 5-hydroxytryptamine 2a receptor agonist, 5-hydroxytryptamine 2b receptor agonist, 5-hydroxytryptamine 2c receptor agonist, agonist, animal metabolite and 14 more.

Is 5-Methoxytryptamine hazardous?

5-Methoxytryptamine carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of 5-Methoxytryptamine?

5-Methoxytryptamine is usually classified under HS code 293399 (Heterocyclic compounds with nitrogen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy 5-Methoxytryptamine?

CompoundList lists 60 suppliers of 5-Methoxytryptamine in China, United States, Hong Kong, United Kingdom and 9 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy 5-Methoxytryptamine in India?

1 supplier in India list 5-Methoxytryptamine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of 5-Methoxytryptamine?

Suppliers quote 5-Methoxytryptamine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle 5-Methoxytryptamine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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