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Fungicides

8-Hydroxyquinoline

Also known as quinolin-8-ol, 8-quinolinol, Oxyquinoline

CAS 148-24-3Formula C9H7NOMolar mass 145.16 g/molEC 205-711-1
GHS signal word: Danger. Pictograms: Corrosive, Acute toxicity (severe), Serious health hazard, Hazardous to the environment 155 suppliers listed Drug substance
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8-Hydroxyquinoline chemical structure, C9H7NO, CAS 148-24-3
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
White crystals or white crystalline powder
Melting point
73 to 75
Boiling point
Ca. 267
Density
1.034 @ 20 ยฐC
Solubility
1 part in 1500 parts water
HS code
293349
Category
Fungicides
UN number
UN 2811
Illustrative photo, off-white crystalline powder in fibre drums in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is 8-Hydroxyquinoline?

Plain description, key identifiers and synonyms

Quinolin-8-ol is a monohydroxyquinoline that is quinoline substituted by a hydroxy group at position 8. Its fungicidal properties are used for the control of grey mould on vines and tomatoes. It has a role as an antibacterial agent, an iron chelator, an antiseptic drug and an antifungal agrochemical. It derives from a hydride of a quinoline.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
quinolin-8-ol
CAS number
148-24-3 CAS number cross-checkedOther or deprecated CAS: 14495-13-7, 24804-14-6, 84063-18-3
EC number
205-711-1
Molecular formula
C9H7NO
UNII
5UTX5635HP
MDL number
MFCD00006807
INCI name
OXYQUINOLINE
InChIKey
MCJGNVYPOGVAJF-UHFFFAOYSA-N
InChI
InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H
SMILES (canonical and isomeric)
C1=CC2=C(C(=C1)O)N=CC=C2

Synonyms

  • quinolin-8-ol
  • 8-quinolinol
  • Oxyquinoline
  • Oxine
  • Quinophenol
  • Oxychinolin
  • Phenopyridine
  • 8-Quinol
  • Bioquin
  • Tumex
  • Oxin
  • Oxybenzopyridine
  • Hydroxybenzopyridine
  • 8-Oxyquinoline
  • 1-Azanaphthalene-8-ol
  • 8-Hydroxychinolin
  • 8-Chinolinol
  • 8-Hydroxy-chinolin
  • Fennosan H 30
  • Fennosan
  • o-Oxychinolin
  • Usaf ek-794
  • Oxyquinol
  • Quinoline, 8-hydroxy-
  • 8 Hydroxyquinoline
Show all 37 synonyms
  • 8 Oxyquinoline
  • 8 Quinolinol
  • UDDER BALM
  • 8-Oxychinolin
  • 8-hydroxy-quinoline
  • Oxoquinoline
  • 8-hydroxy quinoline
  • Procaterol Impurity 12
  • quinoline-8-ol
  • Oxyquinoline (USAN)
  • Oxine, 8-Hydroxyquinoline, Quinophenol, 8-Quinolinone
  • Fennosan HF-15

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
White crystals or white crystalline powderexp.
Odour
Phenolic odorexp.
Melting point
73 to 75exp.
Boiling point
Ca. 267exp.
Density
1.034 @ 20 ยฐCexp.
Solubility
1 part in 1500 parts waterexp.
Vapour pressure
1.66 ร— 10โปยณ mm Hg @ 25 ยฐCexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
145.16 g/molcalc.
Exact mass
145.0528 Dacalc.
LogP (octanol/water)
1.94calc.
Topological polar surface area
33.12 ร…ยฒcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
0calc.
Heavy atoms
11calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2ncccc2c1

c1ccc2ncccc2c1

2 rings, 10 atoms, the Quinoline ring system.

21,766 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H301Toxic if swallowed.
  • H317May cause an allergic skin reaction.
  • H318Causes serious eye damage.
  • H360DMay damage the unborn child.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (20)
  • P203Obtain, read and follow all safety instructions before use.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 2811

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

8-Hydroxyquinoline suppliers

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All 155 suppliers
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Where suppliers are based

155 suppliers in 21 countries

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8-Hydroxyquinoline price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Chemical intermediate for the anti-infective agent, oxyquinoline benzoate, for the fungicide, copper 8-quinolinate, for diiodohydroxyquin, for fungicidal salts in textile products, antiseptic in numerous applications, stabilizer for hydrogen peroxide.

Analytical colorimetric reagent & for precipitation & separation of metals, prepn of number of derivatives used in medicine & industrial applications, used to make its copper chelate, copper 8-hydroxyquinolate for fungicide in agricultural & indust applications, used in manufacture of dyes.

Corrosion inhibitor.

Use classes: Cosmetics, Bactericides, Fungicides.

Cosmetic ingredient, INCI name OXYQUINOLINE(antimicrobial, chelating)

Roles

  • agrochemical
  • antibacterial agent
  • antifungal agent
  • antifungal agrochemical
  • antiinfective agent
  • antimicrobial agent
  • antiseptic drug
  • chelator
  • fungicide
  • iron chelator
  • ligand
  • pesticide
  • pharmaceutical

Functional uses

  • Stabilizing agent

Cosmetic functions

  • Antimicrobial
  • Chelating

How it is made

Reaction of o-aminophenol with o-nitrophenol, glycerol & sulfuric acid, or by hydrolysis of quinoline-8-sulfonic acid

By sulfonation fusion of quinoline, by hydrolysis of 8-chloroquinoline (93% (yield) or by a modified Skraup method with o-aminophenol (80% yield).

Acid hydrolysis of the appropriate aminoquinoline at temps 180-235 ยฐC.

Regulatory status

Inventories, regulations and trade controls that list this substance

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 613-324-00-8

Health and food

  • EU cosmetic ingredient inventory
  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: Hydroxy-8-quinoline and its sulphate bis(8-hydroxyquinolinium) sulphate, except for the uses of the sulphate provided for in entry 51 of Annex III, Refโ€ฆ
  • Active ingredient in FDA approved drug labels

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 8-Hydroxyquinoline is traded under.

HS 2933.49Indicative HS code

Compounds containing in the structure a quinoline or isoquinoline ring-system (whetherโ€ฆ

World exports in 2024
$939M
โˆ’14.6% vs 2023, imports $1.48B
2019 to 2024
Top exporters
  1. China30.1%
  2. India * partner reported16.7%
  3. Switzerland * partner reported14.1%
Top importers
  1. United Kingdom19.2%
  2. Germany16.0%
  3. Romania8.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for 8-Hydroxyquinoline is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 8-Hydroxyquinoline, based on the data on this page

What is 8-Hydroxyquinoline?

Quinolin-8-ol is a monohydroxyquinoline that is quinoline substituted by a hydroxy group at position 8. Its fungicidal properties are used for the control of grey mould on vines and tomatoes. It has a role as an antibacterial agent, an iron chelator, an antiseptic drug and an antifungal agrochemical.

What is the CAS number of 8-Hydroxyquinoline?

The CAS registry number of 8-Hydroxyquinoline is 148-24-3. Other or deprecated CAS numbers: 14495-13-7, 24804-14-6, 84063-18-3.

What is the molecular formula and weight of 8-Hydroxyquinoline?

The molecular formula of 8-Hydroxyquinoline is C9H7NO and its molar mass is 145.16 g/mol.

What is 8-Hydroxyquinoline used for?

Chemical intermediate for the anti-infective agent, oxyquinoline benzoate, for the fungicide, copper 8-quinolinate, for diiodohydroxyquin, for fungicidal salts in textile products, antiseptic in numerous applications, stabilizer for hydrogen peroxide.

Is 8-Hydroxyquinoline hazardous?

8-Hydroxyquinoline carries the GHS signal word "Danger". Main hazards: toxic if swallowed, may cause an allergic skin reaction, causes serious eye damage. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of 8-Hydroxyquinoline?

8-Hydroxyquinoline is usually classified under HS code 293349 (Compounds containing in the structure a quinoline or isoquinoline ring-system (whetherโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy 8-Hydroxyquinoline?

CompoundList lists 155 suppliers of 8-Hydroxyquinoline in China, United States, India, Germany and 17 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy 8-Hydroxyquinoline in India?

12 suppliers in India list 8-Hydroxyquinoline on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of 8-Hydroxyquinoline?

Suppliers quote 8-Hydroxyquinoline on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle 8-Hydroxyquinoline

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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