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Insecticides and acaricides

Acephate

Also known as Orthene, Acetamidophos, Ortran

CAS 30560-19-1Formula C4H10NO3PSMolar mass 183.17 g/molEC 250-241-2
GHS signal word: Warning. Pictograms: Harmful or irritant 199 suppliers listed
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Acephate chemical structure, C4H10NO3PS, CAS 30560-19-1
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Colorless crystals
Melting point
82 to 89
Density
1.4 g/cm³
Solubility
In water, 818,000 mg/L at 25 °C
HS code
293090
Category
Insecticides and acaricides
UN number
UN 3018
Illustrative photo, colourless crystals in small glass vials on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Acephate?

Plain description, key identifiers and synonyms

Acephate is a phosphoramide that is methamidophos in which one of the hydrogens is replaced by an acetyl group. It has a role as an acaricide, an agrochemical and an EC 3.1.1.7 (acetylcholinesterase) inhibitor. It is a phosphoramide, an organothiophosphate insecticide, an organic thiophosphate and a mixed diacylamine. It is functionally related to a member of methamidophos.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-[methoxy(methylsulfanyl)phosphoryl]acetamide
CAS number
30560-19-1 CAS number cross-checked
EC number
250-241-2
Molecular formula
C4H10NO3PS
UNII
3Y417O444D
MDL number
MFCD00055361
InChIKey
YASYVMFAVPKPKE-UHFFFAOYSA-N
InChI
InChI=1S/C4H10NO3PS/c1-4(6)5-9(7,8-2)10-3/h1-3H3,(H,5,6,7)
SMILES (canonical and isomeric)
CC(=O)NP(=O)(OC)SC

Synonyms

  • Orthene
  • Acetamidophos
  • Ortran
  • N-[methoxy(methylsulfanyl)phosphoryl]acetamide
  • Ortril
  • Acetylphosphoramidothioic acid O,S-dimethyl ester
  • Acephat
  • Chevron Orthene
  • O,S-Dimethylacetylphosphoroamidothioate
  • Acephate, technical
  • Chevron RE 12,420
  • Ortho 124120
  • Phosphoramidothioic acid, acetyl-, O,S-dimethyl ester
  • N-(Methoxy(methylthio)phosphinoyl)acetamide
  • O,S-Dimethyl acetylphosphoramidothioate
  • 75 SP
  • ENT 27822
  • RE 12420
  • o,S-Dimethyl acetylamidothiophosphate
  • O,S-dimethyl acetylphosphoroamidothioate
  • N-(methoxy(methylsulfanyl)phosphoryl)acetamide
  • O,S-dimethyl N-acetyl phosphoramidothioate
  • O,S-Dimethyl N-acetylphosphoramidothioate
  • Orthene-755
  • Phosphoramidothioic acid, N-acetyl-, O,S-dimethyl ester
Show all 31 synonyms
  • O,S-Dimethyl N-acetylphosphoramidothiolate
  • Ortho 12420
  • Acefate
  • Acephate (Standard)
  • N-(Methoxy(methylthio)phosphoryl)acetamide
  • DivK1c_006616

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless crystalsexp.
Melting point
82 to 89exp.
Density
1.4 g/cm³exp.
Solubility
In water, 818,000 mg/L at 25 °Cexp.
Vapour pressure
1.7 × 10⁻⁶ mm Hg at 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
183.17 g/molcalc.
Exact mass
183.0119 Dacalc.
LogP (octanol/water)
1.24calc.
Topological polar surface area
55.4 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
3calc.
Heavy atoms
10calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.75calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 3018

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Acephate suppliers

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All 199 suppliers
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Where suppliers are based

199 suppliers in 17 countries

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Acephate price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Insecticide, For use on beans, Brussels sprouts, cauliflower, celery, cotton, cranberries, head lettuce, mint, peanuts, peppers, tobacco, ornamentals, and forests.

Acephate ... is used to control insects and aphids in ornamentals, where it has a reasonably broad spectrum. It is also cleared for use on beans, cotton, head lettuce, celery, soybeans, and bell peppers. It controls parasites of cattle, goats, hogs, horses, poultry, and sheep, where tolerances have been set for milk, eggs, fat, and meat.

Acephate ... is used for household use or golf course spray. (From table).

Use classes: Insecticides, Pesticides.

Pharmacological actions

  • Insecticides

Roles

  • acaricide
  • agrochemical
  • enzyme inhibitor
  • pesticide

Functional uses

  • Biocide

Pharmacology

Acephate is a synthetic organic thiophosphate compound and weak organophosphate acetylcholinesterase inhibitor that is used as a pesticide. It is characterized as a moderately persistent and highly soluble colorless to white solid, and exposure occurs by inhalation, contact, or ingestion.

How it is made

Produced by acetylation of O,O-dimethyl phosphoroamidothioate followed by isomerization.

Acephate may be produced by the acetylation of O,O-dimethylphosphoroamidothioate, (which is prepared from O,O-dimethylphosphorothioic acid chloride and ammonia).

Preparation and activity: Magee, US 3716600 and US 3845172 (1973, 1974 both to Chevron).

Regulatory status

Inventories, regulations and trade controls that list this substance

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 015-079-00-7

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Acephate is traded under.

HS 2930.90Indicative HS code

Organo-sulphur compounds, other

World exports in 2024
$5.83B
+0.1% vs 2023, imports $5.93B
2019 to 2024
Top exporters
  1. China40.7%
  2. United States10.9%
  3. Japan9.3%
Top importers
  1. United States13.3%
  2. Brazil12.6%
  3. China6.6%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Acephate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Acephate, based on the data on this page

What is Acephate?

Acephate is a phosphoramide that is methamidophos in which one of the hydrogens is replaced by an acetyl group. It has a role as an acaricide, an agrochemical and an EC 3.1.1.7 (acetylcholinesterase) inhibitor. It is a phosphoramide, an organothiophosphate insecticide, an organic thiophosphate and a mixed diacylamine.

What is the CAS number of Acephate?

The CAS registry number of Acephate is 30560-19-1.

What is the molecular formula and weight of Acephate?

The molecular formula of Acephate is C4H10NO3PS and its molar mass is 183.17 g/mol.

What is Acephate used for?

Insecticide, For use on beans, Brussels sprouts, cauliflower, celery, cotton, cranberries, head lettuce, mint, peanuts, peppers, tobacco, ornamentals, and forests. Acephate ... is used to control insects and aphids in ornamentals, where it has a reasonably broad spectrum.

Is Acephate hazardous?

Acephate carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Acephate?

Acephate is usually classified under HS code 293090 (Organo-sulphur compounds, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Acephate?

CompoundList lists 199 suppliers of Acephate in Brazil, China, India, United States and 13 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Acephate in India?

40 suppliers in India list Acephate on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Acephate?

Suppliers quote Acephate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Acephate

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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