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Central nervous system drugs

Acepromazine

Also known as Acetylpromazine, Acetopromazine, Acepromazina

CAS 61-00-7Formula C19H22N2OSMolar mass 326.47 g/molEC 200-496-0
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Harmful or irritant 21 suppliers listed Drug substance
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Acepromazine chemical structure, C19H22N2OS, CAS 61-00-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
61-00-7
Formula
C19H22N2OS
Molar mass
326.47 g/mol
EC number
200-496-0
HS code
293430
Category
Central nervous system drugs

What is Acepromazine?

Plain description, key identifiers and synonyms

Acepromazine is a member of the class of phenothiazines that is 10H-phenothiazine substituted by an acetyl group at position 2 and a 3-(dimethylamino)propyl group at position 10. It has a role as a phenothiazine antipsychotic drug. It is a member of phenothiazines, a tertiary amino compound, a methyl ketone and an aromatic ketone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]ethanone
CAS number
61-00-7 CAS number cross-checked
EC number
200-496-0
Molecular formula
C19H22N2OS
UNII
54EJ303F0R
InChIKey
NOSIYYJFMPDDSA-UHFFFAOYSA-N
InChI
InChI=1S/C19H22N2OS/c1-14(22)15-9-10-19-17(13-15)21(12-6-11-20(2)3)16-7-4-5-8-18(16)23-19/h4-5,7-10,13H,6,11-12H2,1-3H3
SMILES (canonical and isomeric)
CC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CCCN(C)C

Synonyms

  • Acetylpromazine
  • Acetopromazine
  • Acepromazina
  • Atravet
  • Acezine 2
  • Acepromazinum
  • 10-(3-Dimethylaminopropyl)phenothiazin-3-yl methyl ketone
  • Concentrat vo34
  • 10-(3-Dimethylaminopropyl)phenothiazine-3-ethylone
  • Ethanone, 1-(10-(3-(dimethylamino)propyl)-10H-phenothiazin-2-yl)-
  • 1-(10-(3-(Dimethylamino)propyl)-10H-phenothiazin-2-yl)ethanone
  • Ethanone, 1-[10-[3-(dimethylamino)propyl]-10H-phenothiazin-2-yl]-
  • 1-[10-(3-Dimethylamino-propyl)-10H-phenothiazin-2-yl]-ethanone
  • 1-{10-[3-(dimethylamino)propyl]-10H-phenothiazin-2-yl}ethanone
  • 1-{10-[3-(dimethylamino)propyl]-10H-phenothiazin-2-yl}ethan-1-one
  • 1-(10-(3-(dimethylamino)propyl)-10H-phenothiazin-2-yl)ethan-1-one
  • 1-(10-(3-Dimethylamino-propyl)-10H-phenothiazin-2-yl)-ethanone
  • Azepromazine
  • Notensil
  • Plivafen
  • Atsetozin
  • Acepromazin
  • Acetacin
  • Acetazin
  • Promazine, acetyl-
Show all 34 synonyms
  • 2-Acetylpromazine
  • 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]ethanone
  • 2-Acetyl-10-(3-dimethylaminopropyl)phenothiazine
  • AY-57,062
  • Acepromazine (INN)
  • 3-Acetyl-10-(3-dimethylaminopropyl)phenothiazine
  • 10-[3-(dimethylamino)propyl]phenothiazin-2-yl methyl ketone
  • Ketone, 10-(3-(dimethylamino)propyl)phenothiazin-2-yl methyl
  • PMZ

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
326.47 g/molcalc.
Exact mass
326.1453 Dacalc.
LogP (octanol/water)
4.44calc.
Topological polar surface area
23.55 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
5calc.
Heavy atoms
23calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.32calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2c(c1)Nc1ccccc1S2

c1ccc2c(c1)Nc1ccccc1S2

3 rings, 14 atoms, the Phenothiazine ring system.

1,001 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H301Toxic if swallowed.
  • H311Toxic in contact with skin.
  • H315Causes skin irritation.
  • H317May cause an allergic skin reaction.
  • H319Causes serious eye irritation.
  • H331Toxic if inhaled.
  • H335May cause respiratory irritation.
Precautionary statements (24)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P316Get emergency medical help immediately.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Acepromazine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 21 suppliers
21 of 21 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

21 suppliers in 7 countries

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Acepromazine price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Industries and functions

Pharmacological actions

  • Antipsychotic Agents
  • Dopamine Antagonists

Roles

  • antipsychotic agent
  • central nervous system depressant
  • central nervous system drug
  • first generation antipsychotic
  • pharmaceutical
  • phenothiazine antipsychotic drug
  • psychotropic drug
  • tranquilizing drug

Pharmacology

Acepromazine is a phenothiazine derivative with depressant effect on the central nervous system. Acepromazine acts as a dopamine receptor antagonist in the CNS, thereby causing sedation, muscular relaxation and a reduction in spontaneous activity. Its fast-acting neuroleptic effect with low toxicity is of particular value in veterinary medicine.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Acepromazine is traded under.

HS 2934.30Indicative HS code

Compounds containing in the structure a phenothiazine ring-system (whether or not…

World exports in 2024
$89.3M
−7.1% vs 2023, imports $97M
2019 to 2024
Top exporters
  1. Germany21.6%
  2. France * partner reported14.6%
  3. China13.0%
Top importers
  1. United States14.2%
  2. Brazil12.7%
  3. India * partner reported10.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Acepromazine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Acepromazine, based on the data on this page

What is Acepromazine?

Acepromazine is a member of the class of phenothiazines that is 10H-phenothiazine substituted by an acetyl group at position 2 and a 3-(dimethylamino)propyl group at position 10. It has a role as a phenothiazine antipsychotic drug.

What is the CAS number of Acepromazine?

The CAS registry number of Acepromazine is 61-00-7.

What is the molecular formula and weight of Acepromazine?

The molecular formula of Acepromazine is C19H22N2OS and its molar mass is 326.47 g/mol.

What is Acepromazine used for?

Use classes: Pharmaceuticals.

Is Acepromazine hazardous?

Acepromazine carries the GHS signal word "Danger". Main hazards: toxic if swallowed, toxic in contact with skin, causes skin irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Acepromazine?

Acepromazine is usually classified under HS code 293430 (Compounds containing in the structure a phenothiazine ring-system (whether or not…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Acepromazine?

CompoundList lists 21 suppliers of Acepromazine in United States, China, France, Hungary and 3 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Acepromazine?

Suppliers quote Acepromazine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Acepromazine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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