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Cardiovascular and metabolic drugs

Alprostadil

Also known as Prostaglandin E1, Caverject, Edex

CAS 745-65-3Formula C20H34O5Molar mass 354.49 g/molEC 212-017-2
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Serious health hazard 116 suppliers listed Drug substance
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Alprostadil chemical structure, C20H34O5, CAS 745-65-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
745-65-3
Formula
C20H34O5
Molar mass
354.49 g/mol
EC number
212-017-2
HS code
293750
Category
Cardiovascular and metabolic drugs

What is Alprostadil?

Plain description, key identifiers and synonyms

Prostaglandin E1 is a prostaglandins E. It has a role as a vasodilator agent, an anticoagulant, a platelet aggregation inhibitor and a human metabolite. It is a conjugate acid of a prostaglandin E1(1-).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid
CAS number
745-65-3 CAS number cross-checked
EC number
212-017-2
Molecular formula
C20H34O5
UNII
F5TD010360
MDL number
MFCD00077860
InChIKey
GMVPRGQOIOIIMI-DWKJAMRDSA-N
InChI
InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1
Canonical SMILES
CCCCCC(O)C=CC1C(O)CC(=O)C1CCCCCCC(=O)O
Isomeric SMILES
CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1CCCCCCC(=O)O)O)O

Synonyms

  • Prostaglandin E1
  • Caverject
  • Edex
  • Muse
  • Alprostadilum
  • Befar
  • Prostin VR Pediatric
  • Vitaros
  • Prink
  • Prostavasin
  • (11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid
  • Caverject Impulse
  • PGE1alpha
  • Lipo PGE1
  • Prostaglandin E1alpha
  • 11alpha,15alpha-Dihydroxy-9-oxo-13-trans-prostenoic acid
  • (13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate
  • 7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid
  • 9-oxo-11R,15S-dihydroxy-13E-prostaenoic acid
  • Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11alpha,13E,15S)-
  • Prostine VR
  • 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid
  • Lipo-PGE1
  • Viridal duo
  • 7-((1R,2R,3R)-3-hydroxy-2-((E,3S)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)heptanoic acid
Show all 38 synonyms
  • Viridal 5
  • 7-((1R,2R,3R)-3-Hydroxy-2-((1E,3S)-3-hydroxyoct-1-en-1-yl)-5-oxocyclopentyl)heptanoic acid
  • Viridal 10
  • Viridal 20
  • Muse (intraurethral alprostadil suppository)
  • Prostin
  • Prostandin
  • Prostin VR
  • l-Prostaglandin E1
  • Vasaprostan
  • Femprox
  • Topiglan
  • Liprostin

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
354.49 g/molcalc.
Exact mass
354.2406 Dacalc.
LogP (octanol/water)
3.48calc.
Topological polar surface area
94.83 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
13calc.
Heavy atoms
25calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.8calc.
Formal charge
0calc.
Stereocentres
4calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CCCC1

O=C1CCCC1

1 ring, 6 atoms, the Cyclopentanone ring system.

1,367 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H301Toxic if swallowed.
  • H361Suspected of damaging fertility or the unborn child.
Precautionary statements (10)
  • P203Obtain, read and follow all safety instructions before use.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P318If exposed or concerned, get medical advice.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Alprostadil suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 116 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

116 suppliers in 19 countries

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Alprostadil price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Platelet Aggregation Inhibitors
  • Urological Agents
  • Vasodilator Agents

Roles

  • animal metabolite
  • anticoagulant
  • antimicrobial agent
  • antineoplastic agent
  • antiviral agent
  • cardiovascular drug
  • eukaryotic metabolite
  • hematologic agent
  • human metabolite
  • mammalian metabolite
  • metabolite
  • ophthalmology drug
  • pharmaceutical
  • platelet aggregation inhibitor
  • protective agent
  • renoprotective agent
  • vasodilator agent

Pharmacology

Alprostadil is a Prostaglandin Analog and Prostaglandin E1 Agonist. The mechanism of action of alprostadil is as a Prostaglandin Receptor Agonist. The physiologic effect of alprostadil is by means of Genitourinary Arterial Vasodilation and Venous Vasodilation.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Alprostadil is traded under.

HS 2937.50Indicative HS code

Prostaglandins, thromboxanes and leukotrienes, their derivatives and structural analogues

World exports in 2024
$270M
+9.1% vs 2023, imports $304M
2019 to 2024
Top exporters
  1. Hungary22.8%
  2. Czech Republic21.6%
  3. South Korea14.6%
Top importers
  1. Japan17.0%
  2. Italy13.1%
  3. Germany10.4%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Alprostadil is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Alprostadil, based on the data on this page

What is Alprostadil?

Prostaglandin E1 is a prostaglandins E. It has a role as a vasodilator agent, an anticoagulant, a platelet aggregation inhibitor and a human metabolite. It is a conjugate acid of a prostaglandin E1(1-).

What is the CAS number of Alprostadil?

The CAS registry number of Alprostadil is 745-65-3.

What is the molecular formula and weight of Alprostadil?

The molecular formula of Alprostadil is C20H34O5 and its molar mass is 354.49 g/mol.

What is Alprostadil used for?

Known uses and roles of Alprostadil include cardiovascular drugs in pharmaceuticals, hormones and steroids in pharmaceuticals, animal metabolite, anticoagulant, antimicrobial agent and 17 more.

Is Alprostadil hazardous?

Alprostadil carries the GHS signal word "Danger". Main hazards: toxic if swallowed, suspected of damaging fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Alprostadil?

Alprostadil is usually classified under HS code 293750 (Prostaglandins, thromboxanes and leukotrienes, their derivatives and structural analogues). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Alprostadil?

CompoundList lists 116 suppliers of Alprostadil in United States, China, United Kingdom, India and 15 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Alprostadil in India?

4 suppliers in India list Alprostadil on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Alprostadil?

Suppliers quote Alprostadil on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Alprostadil

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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