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Hormones and steroids

Prostaglandin E2

Also known as Dinoprostone, Prostin E2, Prepidil

CAS 363-24-6Formula C20H32O5Molar mass 352.47 g/molEC 206-656-6
GHS signal word: Danger. Pictograms: Harmful or irritant, Serious health hazard 79 suppliers listed Drug substance
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Prostaglandin E2 chemical structure, C20H32O5, CAS 363-24-6
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
363-24-6
Formula
C20H32O5
Molar mass
352.47 g/mol
EC number
206-656-6
HS code
293750
Category
Hormones and steroids

What is Prostaglandin E2?

Plain description, key identifiers and synonyms

Prostaglandin E2 is prostaglandin F2alpha in which the hydroxy group at position 9 has been oxidised to the corresponding ketone. Prostaglandin E2 is the most common and most biologically potent of mammalian prostaglandins. It has a role as an oxytocic, a mouse metabolite and a human metabolite. It is a conjugate acid of a prostaglandin E2(1-).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid
CAS number
363-24-6 CAS number cross-checkedOther or deprecated CAS: 22230-04-2
EC number
206-656-6
Molecular formula
C20H32O5
UNII
K7Q1JQR04M
MDL number
MFCD00077861
InChIKey
XEYBRNLFEZDVAW-ARSRFYASSA-N
InChI
InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1
Canonical SMILES
CCCCCC(O)C=CC1C(O)CC(=O)C1CC=CCCCC(=O)O
Isomeric SMILES
CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1C/C=C\CCCC(=O)O)O)O

Synonyms

  • Dinoprostone
  • Prostin E2
  • Prepidil
  • Cervidil
  • Minprostin E2
  • Propess
  • Minprositin E2
  • Dinoproston
  • Dinoprostonum
  • Cerviprost
  • Dinoprostona
  • Enzaprost E
  • Cerviprime
  • Prostenone
  • PGE2alpha
  • (5Z,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
  • Prostaglandin E2alpha
  • (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid
  • Prostaglandin E(2)
  • (Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid
  • (5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
  • (5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate
  • Dinoprostone beta-Cyclodextrin Clathrate
  • 5-Heptenoic acid, 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-
  • Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, (5Z,11alpha,13E,15S)-
Show all 39 synonyms
  • (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate
  • Prosta-5,13-dien-1-oic acid, (5Z,11-alpha,13E,15S)-11,15-dihydroxy-9-oxo-
  • PGE2 alpha
  • Prostaglandin E2 alpha
  • 5-Heptenoic acid, 7-[3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-
  • Gel, Prepidil
  • E2, Prostaglandin
  • (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid
  • alpha, PGE2
  • E2alpha, Prostaglandin
  • alpha, Prostaglandin E2
  • E2 alpha, Prostaglandin
  • (E,Z)-(1R,2R,3R)-7-[3-hydroxy-2-[(3S)-(3-hydroxy-1-octenyl)]-5-oxocyclopentyl]-5-heptenoic acid
  • (Z)-7-((1R,2R,3R)-3-hydroxy-2-((E,3S)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
352.47 g/molcalc.
Exact mass
352.225 Dacalc.
LogP (octanol/water)
3.25calc.
Topological polar surface area
94.83 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
12calc.
Heavy atoms
25calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.7calc.
Formal charge
0calc.
Stereocentres
4calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CCCC1

O=C1CCCC1

1 ring, 6 atoms, the Cyclopentanone ring system.

1,367 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H302Harmful if swallowed.
  • H360May damage fertility or the unborn child.
Precautionary statements (9)
  • P203Obtain, read and follow all safety instructions before use.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Prostaglandin E2 suppliers

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All 79 suppliers
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Where suppliers are based

79 suppliers in 18 countries

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Prostaglandin E2 price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Oxytocics

Roles

  • analgesic
  • animal metabolite
  • antineoplastic agent
  • eukaryotic metabolite
  • human metabolite
  • mammalian metabolite
  • metabolite
  • mouse metabolite
  • oxytocic
  • pharmaceutical

Pharmacology

Dinoprostone is a Prostaglandin Analog.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Prostaglandin E2 is traded under.

HS 2937.50Indicative HS code

Prostaglandins, thromboxanes and leukotrienes, their derivatives and structural analogues

World exports in 2024
$270M
+9.1% vs 2023, imports $304M
2019 to 2024
Top exporters
  1. Hungary22.8%
  2. Czech Republic21.6%
  3. South Korea14.6%
Top importers
  1. Japan17.0%
  2. Italy13.1%
  3. Germany10.4%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Prostaglandin E2 is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Prostaglandin E2, based on the data on this page

What is Prostaglandin E2?

Prostaglandin E2 is prostaglandin F2alpha in which the hydroxy group at position 9 has been oxidised to the corresponding ketone. Prostaglandin E2 is the most common and most biologically potent of mammalian prostaglandins. It has a role as an oxytocic, a mouse metabolite and a human metabolite.

What is the CAS number of Prostaglandin E2?

The CAS registry number of Prostaglandin E2 is 363-24-6. Other or deprecated CAS numbers: 22230-04-2.

What is the molecular formula and weight of Prostaglandin E2?

The molecular formula of Prostaglandin E2 is C20H32O5 and its molar mass is 352.47 g/mol.

What is Prostaglandin E2 used for?

Known uses and roles of Prostaglandin E2 include hormones and steroids in pharmaceuticals, analgesic, animal metabolite, antineoplastic agent, eukaryotic metabolite and 7 more.

Is Prostaglandin E2 hazardous?

Prostaglandin E2 carries the GHS signal word "Danger". Main hazards: harmful if swallowed, may damage fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Prostaglandin E2?

Prostaglandin E2 is usually classified under HS code 293750 (Prostaglandins, thromboxanes and leukotrienes, their derivatives and structural analogues). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Prostaglandin E2?

CompoundList lists 79 suppliers of Prostaglandin E2 in China, United States, Germany, United Kingdom and 14 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Prostaglandin E2 in India?

3 suppliers in India list Prostaglandin E2 on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Prostaglandin E2?

Suppliers quote Prostaglandin E2 on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Prostaglandin E2

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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