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Aromatic building blocks

Alverine

Also known as Phenopropamine, Phenpropamine, Profenil

CAS 150-59-4Formula C20H27NMolar mass 281.44 g/molEC 205-763-5
GHS signal word: Warning. Pictograms: Harmful or irritant 13 suppliers listed
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Alverine chemical structure, C20H27N, CAS 150-59-4
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Liquid
Boiling point
165 to 168
Solubility
SIRUP, SOL IN WATER /HYDROCHLORIDE/
HS code
292149
Category
Aromatic building blocks
Illustrative photo, closed blue jerry cans in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Alverine?

Plain description, key identifiers and synonyms

Alverine is a tertiary amine having one ethyl and two 3-phenylprop-1-yl groups attached to the nitrogen. An antispasmodic that acts directly on intestinal and uterine smooth muscle, it is used (particularly as the citrate salt) in the treatment of irritable bowel syndrome. It has a role as an antispasmodic drug. It is a conjugate base of an alverine(1+).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine
CAS number
150-59-4 CAS number cross-checkedOther or deprecated CAS: 5560-59-8
EC number
205-763-5
Molecular formula
C20H27N
UNII
46TIR1560O
MDL number
MFCD00075035
InChIKey
ZPFXAOWNKLFJDN-UHFFFAOYSA-N
InChI
InChI=1S/C20H27N/c1-2-21(17-9-15-19-11-5-3-6-12-19)18-10-16-20-13-7-4-8-14-20/h3-8,11-14H,2,9-10,15-18H2,1H3
SMILES (canonical and isomeric)
CCN(CCCC1=CC=CC=C1)CCCC2=CC=CC=C2

Synonyms

  • Phenopropamine
  • Phenpropamine
  • Profenil
  • Dipropylin
  • Dipropyline
  • Sestron
  • Di(phenylpropyl)ethylamine
  • N-Ethyl-3,3'-diphenyldipropylamine
  • Alverina
  • Sestron base
  • Bis(gamma-phenylpropyl)ethylamine
  • ethylbis(3-phenylpropyl)amine
  • Alverinum
  • N,N-Bis(3-phenylpropyl)ethylamine
  • N-Ethyl-N-(3-phenylpropyl)benzenepropanamine
  • Dipropylamine, N-ethyl-3,3'-diphenyl-
  • N-Ethyl-3-phenyl-N-(3-phenylpropyl)-1-propanamine
  • Benzenepropanamine, N-ethyl-N-(3-phenylpropyl)-
  • N-ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine
  • N-Ethyl-bis(3-phenylpropyl)amin
  • Alverine (INN)
  • Meteospasmyl
  • Alverine citrate(USAN)
  • DivK1c_000312
  • citric acid, ethyl-bis(3-phenylpropyl)amine
Show all 27 synonyms
  • N-Ethyl-3-phenyl-N-(3-phenylpropyl)-1-propanamine #
  • N-ethyl-3-phenyl-N-(3-phenylpropyl)-1-propanamine, 2-hydroxypropane-1,2,3-tricarboxylic acid

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Liquidexp.
Boiling point
165 to 168exp.
Solubility
SIRUP, SOL IN WATER /HYDROCHLORIDE/exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
281.44 g/molcalc.
Exact mass
281.2144 Dacalc.
LogP (octanol/water)
4.57calc.
Topological polar surface area
3.24 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
9calc.
Heavy atoms
21calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.4calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(CCCNCCCc2ccccc2)cc1

c1ccc(CCCNCCCc2ccccc2)cc1

2 rings, 19 atoms, the Bis-(3-phenyl-propyl)-amine ring system.

21 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H312Harmful in contact with skin.
  • H332Harmful if inhaled.
Precautionary statements (13)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P317Get medical help.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Alverine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 13 suppliers
13 of 13 offers
  • Sinco Pharmachem
    Unclaimed profile
    AlverineGrade, purity and minimum order on request
    Price on request
    View
  • Chemicea
    India ManufacturerUnclaimed profile
    AlverineGrade, purity and minimum order on request
    Price on request
    View
  • Analytica Chemie
    IndiaUnclaimed profile
    AlverineGrade, purity and minimum order on request
    Price on request
    View
  • Chemcopia
    India ManufacturerUnclaimed profile
    AlverineGrade, purity and minimum order on request
    Price on request
    View
  • Enomark Pharma
    India ManufacturerUnclaimed profile
    AlverineGrade, purity and minimum order on request
    Price on request
    View
  • Shanghai Pinewood
    China, ShanghaiUnclaimed profile
    AlverineGrade, purity and minimum order on request
    Price on request
    View
  • Sris Synthesis Pvt Ltd.
    India ManufacturerUnclaimed profile
    AlverineGrade, purity and minimum order on request
    Price on request
    View
  • SynInnova Laboratories Inc.
    United States ManufacturerUnclaimed profile
    AlverineGrade, purity and minimum order on request
    Price on request
    View
  • 1st Scientific LLC
    China, NanjingUnclaimed profile
    AlverineGrade, purity and minimum order on request
    Price on request
    View
  • Hoffman Fine Chemicals
    Australia, BrooklynUnclaimed profile
    AlverineGrade, purity and minimum order on request
    Price on request
    View

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

13 suppliers in 5 countries

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Alverine price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Parasympatholytics

Roles

  • antihypertensive agent
  • antispasmodic drug
  • cardiovascular drug
  • muscle relaxant
  • neuromuscular agent
  • pharmaceutical

How it is made

Prepd from phenylpropyl chloride & ethylamine in alkaline medium: kulz et al, ber 72, 2165 (1939), alternate route: stuhner, elbrachter, arch pharm 287, 139 (1954).

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Alverine is traded under.

HS 2921.49Indicative HS code

Aromatic monoamines and their derivatives, salts thereof, other

World exports in 2024
$1.14B
+5.6% vs 2023, imports $1.06B
2019 to 2024
Top exporters
  1. Germany23.3%
  2. China19.4%
  3. Singapore14.6%
Top importers
  1. Belgium15.9%
  2. South Korea15.0%
  3. Germany12.8%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Alverine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Alverine, based on the data on this page

What is Alverine?

Alverine is a tertiary amine having one ethyl and two 3-phenylprop-1-yl groups attached to the nitrogen. An antispasmodic that acts directly on intestinal and uterine smooth muscle, it is used (particularly as the citrate salt) in the treatment of irritable bowel syndrome. It has a role as an antispasmodic drug.

What is the CAS number of Alverine?

The CAS registry number of Alverine is 150-59-4. Other or deprecated CAS numbers: 5560-59-8.

What is the molecular formula and weight of Alverine?

The molecular formula of Alverine is C20H27N and its molar mass is 281.44 g/mol.

What is Alverine used for?

Use classes: Pharmaceuticals.

Is Alverine hazardous?

Alverine carries the GHS signal word "Warning". Main hazards: harmful if swallowed, harmful in contact with skin, harmful if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Alverine?

Alverine is usually classified under HS code 292149 (Aromatic monoamines and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Alverine?

CompoundList lists 13 suppliers of Alverine in India, United States, China, Australia and 1 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Alverine in India?

5 suppliers in India list Alverine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Alverine?

Suppliers quote Alverine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Alverine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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