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Hardeners and crosslinkers

Apholate

Also known as Pholate, 1-Aziridinylphosphonitrile trimer, Afolat

CAS 52-46-0Formula C12H24N9P3Molar mass 387.31 g/mol
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Apholate chemical structure, C12H24N9P3, CAS 52-46-0
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
52-46-0
Formula
C12H24N9P3
Appearance
Crystals from heptane
Melting point
147.5 °C
HS code
293499
Category
Hardeners and crosslinkers
Illustrative photo, a shrink wrapped pallet of kraft paper sacks in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Apholate?

Plain description, key identifiers and synonyms

Apholate is a member of the class of aziridines that is 1,3,5,2,4,6-triazatriphosphinine substituted by aziridin-1-yl groups at positions 2,2,4,4,6, and 6. It is an insect sterilant. It has a role as an alkylating agent and an insect sterilant. It is a member of aziridines and a ring assembly. It is functionally related to a 1,3,5,2,4,6-triazatriphosphinine.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2,2,4,4,6,6-hexakis(aziridin-1-yl)-1,3,5-triaza-2λ5,4λ5,6λ5-triphosphacyclohexa-1,3,5-triene
CAS number
52-46-0 CAS number cross-checked
Molecular formula
C12H24N9P3
UNII
MN3Q1B846W
InChIKey
PXZAWHSJYIECNQ-UHFFFAOYSA-N
InChI
InChI=1S/C12H24N9P3/c1-2-16(1)22(17-3-4-17)13-23(18-5-6-18,19-7-8-19)15-24(14-22,20-9-10-20)21-11-12-21/h1-12H2
SMILES (canonical and isomeric)
C1CN1P2(=NP(=NP(=N2)(N3CC3)N4CC4)(N5CC5)N6CC6)N7CC7

Synonyms

  • Pholate
  • 1-Aziridinylphosphonitrile trimer
  • Afolat
  • Hexakis(aziridinyl)phosphotriazine
  • Olin MO. 2174
  • Myko 63
  • ENT 26,316
  • CB 40068
  • Hexa(1-aziridinyl)triphosphotriazine
  • Hexakis-(1-aziridinyl)phosphonitrile
  • SQ 8388
  • 1,3,5,2,4,6-Triazatriphosphorine, 2,2,4,4,6,6-hexakis(1-aziridinyl)-2,2,4,4,6,6-hexahydro-
  • 2,2,4,4,6,6-Hexakis(1-aziridinyl)-2,2,4,4,6,6-hexahydro-1,3,5,2,4,6-triazatriphosphorine
  • Aziridine, 1,3,5,2,4,6-triazatriphosphorine derivative
  • 2,2,4,4,6,6-Hexakis(1-aziridinyl)cyclotriphosphaza-1,3,5-triene
  • Hexakis (1-aziridinyl)phosphonitrilate
  • 1,3,5,2,4,6-Triazatriphosphorine, 2,2,4,4,6,6-hexakis(1-aziridiny l)-2,2,4,4,6,6-hexahydro-
  • APN
  • 2,2,4,4,6,6-Hexaaziridin-1-yl-1,3,5-triaza-2$l^{5},4$l^{5},6$l^{5}-tri phosphacyclohexa-1,3,5-triene
  • 2,2,4,4,6,6-hexakis(aziridin-1-yl)-1,3,5-triaza-2lambda5,4lambda5,6lambda5-triphosphacyclohexa-1,3,5-triene
  • Hexa(1-aziridinyl)-1,3,5-phosphotriazine
  • 2,2,4,4,6,6-Hexahydro-2,2,4,4,6,6-hexakis(1-aziridinyl)-1,3,5,2,4,6-triazatriphosphorine
  • Hexa(1-aziridinyl)triphosphatriazine
  • ENT 26316
  • Hexa(1-aziridinyl)-1,5-phosphotriazine
Show all 34 synonyms
  • Aziridine,3,5,2,4,6-triazatriphosphorine derivative
  • 2,2,4,4,6,6-hexakis(1-aziridinyl)-cyclotriphosphazene
  • 2,4,4,6,6-Hexakis(1-aziridinyl)cyclotriphosphaza-1,3,5-triene
  • 2,4,4,6,6-Hexahydro-2,2,4,4,6,6-hexakis(1-aziridinyl)-1,3,5,2,4,6-triazatriphosphorine
  • 2,4,4,6,6-Hexakis(1-aziridinyl)-2,2,4,4,6,6-hexahydro-1,3,5,2,4,6-triazatriphosphorine
  • 1,5,2,4,6-Triazatriphosphorine, 2,2,4,4,6,6-hexakis(1-aziridinyl)-2,2,4,4,6,6-hexahydro-
  • 2,2,4,4,6,6-hexakis(aziridin-1-yl)-1,3,5,2lambda5,4lambda5,6lambda5-triazatriphosphinine
  • 2,2,4,4,6,6-hexakis(aziridin-1-yl)-1,3,5,2lambda(5),4lambda(5),6lambda(5)-triazatriphosphinine
  • 2,2,4,4,6,6-Hexakis(aziridin-1-yl)-1,3,5,2lambda~5~,4lambda~5~,6lambda~5~-triazatriphosphinine

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystals from heptaneexp.
Melting point
147.5 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
387.31 g/molcalc.
Exact mass
387.1368 Dacalc.
LogP (octanol/water)
1.73calc.
Topological polar surface area
55.14 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
9calc.
Rotatable bonds
6calc.
Heavy atoms
24calc.
Rings
7calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CN1P1(N2CC2)=NP(N2CC2)(N2CC2)=NP(N2CC2)(N2CC2)=N1

C1CN1P1(N2CC2)=NP(N2CC2)(N2CC2)=NP(N2CC2)(N2CC2)=N1

7 rings, 24 atoms. This chemical is the scaffold itself.

1 other chemical share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Apholate suppliers

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Where suppliers are based

1 supplier in 1 country

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Apholate price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Exptl insect chemosterilant.

Use classes: Insecticides.

Roles

  • aetiopathogenetic role
  • alkylating agent
  • chemosterilant
  • genotoxin
  • insect sterilant
  • insecticide
  • mutagen
  • pesticide

How it is made

By addn of aziridine to 2,2,4,4,6,6-hexachloro-2,2,4,4,5,5-hexahydrotriazatriphosphorine, however, it has been produced for research purposes only.

Ratz grundmann, us patent 2,858,306 (1958 to olin mathieson).

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Apholate is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Apholate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Apholate, based on the data on this page

What is Apholate?

Apholate is a member of the class of aziridines that is 1,3,5,2,4,6-triazatriphosphinine substituted by aziridin-1-yl groups at positions 2,2,4,4,6, and 6. It is an insect sterilant. It has a role as an alkylating agent and an insect sterilant. It is a member of aziridines and a ring assembly.

What is the CAS number of Apholate?

The CAS registry number of Apholate is 52-46-0.

What is the molecular formula and weight of Apholate?

The molecular formula of Apholate is C12H24N9P3 and its molar mass is 387.31 g/mol.

What is Apholate used for?

Exptl insect chemosterilant. Use classes: Insecticides.

Is Apholate hazardous?

No GHS hazard classification for Apholate is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Apholate?

Apholate is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Apholate?

CompoundList lists 1 supplier of Apholate in China. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Apholate?

Suppliers quote Apholate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Apholate

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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