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Screening compounds

AZM 475271

Also known as N-(2-chloro-5-methoxyphenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine, N-(2-chloro-5-methoxyphenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine, 4-Quinazolinamine, N-(2-chloro-5-methoxyphenyl)-6-methoxy-7-((1-methyl-4-piperidinyl)methoxy)-

CAS 476159-98-5Formula C23H27ClN4O3Molar mass 442.95 g/molEC 637-153-3
GHS signal word: Danger. Pictograms: Acute toxicity (severe)
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AZM 475271 chemical structure, C23H27ClN4O3, CAS 476159-98-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
476159-98-5
Formula
C23H27ClN4O3
Molar mass
442.95 g/mol
EC number
637-153-3
HS code
293359
Category
Screening compounds

What is AZM 475271?

Plain description, key identifiers and synonyms

Src Kinase Inhibitor M475271 is an inhibitor of Src tyrosine kinase, with potential antineoplastic activity. Upon administration, Src kinase inhibitor M-475271 targets and binds to Src kinase. This inhibits Src-mediated signaling and the proliferation of tumor cells overexpressing Src. Src tyrosine kinase, a non-receptor tyrosine kinase upregulated in many tumor cell types, plays an important role in tumor cell proliferation, motility, invasiveness and survival.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-(2-chloro-5-methoxyphenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
CAS number
476159-98-5 CAS number cross-checked
EC number
637-153-3
Molecular formula
C23H27ClN4O3
UNII
0361Z8214O
MDL number
MFCD19690925
InChIKey
WPOXAFXHRJYEIC-UHFFFAOYSA-N
InChI
InChI=1S/C23H27ClN4O3/c1-28-8-6-15(7-9-28)13-31-22-12-19-17(11-21(22)30-3)23(26-14-25-19)27-20-10-16(29-2)4-5-18(20)24/h4-5,10-12,14-15H,6-9,13H2,1-3H3,(H,25,26,27)
SMILES (canonical and isomeric)
CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=CC(=C4)OC)Cl)OC

Synonyms

  • N-(2-chloro-5-methoxyphenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine
  • N-(2-chloro-5-methoxyphenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
  • 4-Quinazolinamine, N-(2-chloro-5-methoxyphenyl)-6-methoxy-7-((1-methyl-4-piperidinyl)methoxy)-
  • Src Kinase Inhibitor M475271
  • N-(2-chloro-5-methoxyphenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine
  • Methoxy Aniline 7
  • C23H27ClN4O3
  • N-(2-Chloro-5-methoxyphenyl)-6-methoxy
  • AZM475271?
  • N-(2-chloro-5-methoxy-phenyl)-6-methoxy-7-[(1-methyl-4-piperidyl)methoxy]quinazolin-4-amine

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
442.95 g/molcalc.
Exact mass
442.1772 Dacalc.
LogP (octanol/water)
4.76calc.
Topological polar surface area
68.74 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
7calc.
Rotatable bonds
7calc.
Heavy atoms
31calc.
Rings
4calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.39calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(Nc2ncnc3cc(OCC4CCNCC4)ccc23)cc1

c1ccc(Nc2ncnc3cc(OCC4CCNCC4)ccc23)cc1

4 rings, 25 atoms.

16 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)

Hazard statements

  • H301Toxic if swallowed.
Precautionary statements (7)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

AZM 475271 suppliers

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AZM 475271 price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code AZM 475271 is traded under.

HS 2933.59Indicative HS code

Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring, other

World exports in 2024
$18.4B
+10.5% vs 2023, imports $24.8B
2019 to 2024
Top exporters
  1. Ireland43.6%
  2. Switzerland * partner reported26.3%
  3. China7.9%
Top importers
  1. Slovenia30.3%
  2. United States30.1%
  3. Germany15.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for AZM 475271 is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about AZM 475271, based on the data on this page

What is AZM 475271?

Src Kinase Inhibitor M475271 is an inhibitor of Src tyrosine kinase, with potential antineoplastic activity. Upon administration, Src kinase inhibitor M-475271 targets and binds to Src kinase. This inhibits Src-mediated signaling and the proliferation of tumor cells overexpressing Src.

What is the CAS number of AZM 475271?

The CAS registry number of AZM 475271 is 476159-98-5.

What is the molecular formula and weight of AZM 475271?

The molecular formula of AZM 475271 is C23H27ClN4O3 and its molar mass is 442.95 g/mol.

What is AZM 475271 used for?

Known uses and roles of AZM 475271 include building blocks in research and laboratory and screening compounds in research and laboratory.

Is AZM 475271 hazardous?

AZM 475271 carries the GHS signal word "Danger". Main hazards: toxic if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of AZM 475271?

AZM 475271 is usually classified under HS code 293359 (Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy AZM 475271?

Post a free request on CompoundList and suppliers of AZM 475271 will send you quotes. Your contact details stay private until you accept a quote.

What is the price of AZM 475271?

Suppliers quote AZM 475271 on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle AZM 475271

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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