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Central nervous system drugs

Biperiden

Also known as Biperidene, Biperidine, Biperideno

CAS 514-65-8Formula C21H29NOMolar mass 311.47 g/molEC 208-184-6
GHS signal word: Warning. Pictograms: Harmful or irritant 18 suppliers listed
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Biperiden chemical structure, C21H29NO, CAS 514-65-8
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystals
Melting point
101 °C
Solubility
Fluffy white powder, mp 238 °C. Solubility in water (mg/100 mL) at 30 °C: 220 (ph 3.8),…
HS code
293339
Category
Central nervous system drugs
Illustrative photo, closed jumbo bulk bags in a warehouse in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Biperiden?

Plain description, key identifiers and synonyms

Biperiden is a member of the class of piperidines that is N-propylpiperidine in which the methyl hydrogens have been replaced by hydroxy, phenyl, and 5-norbornen-2-yl groups. A muscarinic antagonist affecting both the central and peripheral nervous systems, it is used in the treatment of all forms of Parkinson's disease. It has a role as an antidote to sarin poisoning, an antiparkinson drug, a muscarinic antagonist, a parasympatholytic and an antidyskinesia agent. It is a member of piperidines, a tertiary alcohol and a tertiary amino compound.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-(2-bicyclo[2.2.1]hept-5-enyl)-1-phenyl-3-piperidin-1-ylpropan-1-ol
CAS number
514-65-8 CAS number cross-checked
EC number
208-184-6
Molecular formula
C21H29NO
UNII
0FRP6G56LD
InChIKey
YSXKPIUOCJLQIE-UHFFFAOYSA-N
InChI
InChI=1S/C21H29NO/c23-21(19-7-3-1-4-8-19,11-14-22-12-5-2-6-13-22)20-16-17-9-10-18(20)15-17/h1,3-4,7-10,17-18,20,23H,2,5-6,11-16H2
SMILES (canonical and isomeric)
C1CCN(CC1)CCC(C2CC3CC2C=C3)(C4=CC=CC=C4)O

Synonyms

  • Biperidene
  • Biperidine
  • Biperideno
  • Biperidenum
  • KL 373
  • Akineton-
  • alpha-5-Norbornen-2-yl-alpha-phenyl-1-piperidinepropanol
  • 1-(bicyclo[2.2.1]hept-5-en-2-yl)-1-phenyl-3-(piperidin-1-yl)propan-1-ol
  • alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanol
  • 1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenyl-3-(piperidin-1-yl)propan-1-ol
  • 1-Piperidinepropanol, alpha-bicyclo(2.2.1)hept-5-en-2-yl-alpha-phenyl-
  • alpha-Bicyclo(2.2.1)hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanol
  • 1-Bicyclo(2.2.1)hept-5-en-2-yl-1-phenyl-3-piperidin-1-yl-propan-1-ol
  • 1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-yl-propan-1-ol
  • 1-Piperidinepropanol, alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-
  • 1-(bicyclo(2.2.1)hept-5-en-2-yl)-1-phenyl-3-(piperidin-1-yl)propan-1-ol
  • Hydrochloride, Biperiden
  • Akineton
  • Beperiden
  • Bipariden
  • 1-Bicycloheptenyl-1-phenyl-3-piperidino-propanol-1
  • 3-Piperidino-1-phenyl-1-bicycloheptenyl-1-propanol
  • alpha-(Bicyclo(2.2.1)hept-5-en-2-yl)-alpha-phenyl-1-piperidino propanol
  • 1-PIPERIDINEPROPANOL, alpha-5-NORBORNEN-2-YL-alpha-PHENYL-
  • 3-Piperidino-1-phenyl-1-bicyclo(2.2.1)hepten-(5)-yl-propanol-(1)
Show all 30 synonyms
  • 1-(5-bicyclo[2.2.1]hept-2-enyl)-1-phenyl-3-piperidin-1-ylpropan-1-ol
  • 1-(2-bicyclo[2.2.1]hept-5-enyl)-1-phenyl-3-piperidin-1-ylpropan-1-ol
  • Akineton (TN)
  • 1-Piperidinepropanol, alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-, hydrochloride
  • Biperiden (JAN/USP/INN)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystalsexp.
Melting point
101 °Cexp.
Solubility
Fluffy white powder, mp 238 °C. Solubility in water (mg/100 mL) at 30 °C: 220 (ph 3.8), 280 (pH 5.5), 290 (pH 6.7), 264 (pH 7.9), 244 (pH 9.2-10.1) /Hydrochloride/exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
311.47 g/molcalc.
Exact mass
311.2249 Dacalc.
LogP (octanol/water)
3.96calc.
Topological polar surface area
23.47 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
5calc.
Heavy atoms
23calc.
Rings
4calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.62calc.
Formal charge
0calc.
Stereocentres
4calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1=CC2CC1CC2C(CCN1CCCCC1)c1ccccc1

C1=CC2CC1CC2C(CCN1CCCCC1)c1ccccc1

4 rings, 22 atoms.

9 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Biperiden suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 18 suppliers
18 of 18 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

18 suppliers in 9 countries

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Biperiden price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Therapeutic category: Antiparkinsonian.

Use classes: Pharmaceuticals.

Industries and functions

Pharmacological actions

  • Antiparkinson Agents
  • Muscarinic Antagonists
  • Parasympatholytics

Roles

  • antidepressant
  • antidote
  • antidote to sarin poisoning
  • antidyskinesia agent
  • antiparkinson drug
  • antipsychotic agent
  • anxiolytic drug
  • central nervous system depressant
  • central nervous system drug
  • cholinergic antagonist
  • cholinergic drug
  • muscarinic antagonist
  • neurotransmitter agent
  • parasympatholytic
  • pharmaceutical
  • protective agent
  • psychotropic drug
  • tranquilizing drug

Pharmacology

Biperiden is an Anticholinergic. The mechanism of action of biperiden is as a Cholinergic Antagonist.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Biperiden is traded under.

HS 2933.39Indicative HS code

Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure…

World exports in 2024
$9.16B
−17.9% vs 2023, imports $10.6B
2019 to 2024
Top exporters
  1. China21.5%
  2. India * partner reported12.3%
  3. Ireland11.6%
Top importers
  1. Germany14.2%
  2. United States12.8%
  3. Brazil10.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Biperiden is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Biperiden, based on the data on this page

What is Biperiden?

Biperiden is a member of the class of piperidines that is N-propylpiperidine in which the methyl hydrogens have been replaced by hydroxy, phenyl, and 5-norbornen-2-yl groups.

What is the CAS number of Biperiden?

The CAS registry number of Biperiden is 514-65-8.

What is the molecular formula and weight of Biperiden?

The molecular formula of Biperiden is C21H29NO and its molar mass is 311.47 g/mol.

What is Biperiden used for?

Therapeutic category: Antiparkinsonian. Use classes: Pharmaceuticals.

Is Biperiden hazardous?

Biperiden carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Biperiden?

Biperiden is usually classified under HS code 293339 (Compounds containing an unfused pyridine ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Biperiden?

CompoundList lists 18 suppliers of Biperiden in China, United States, Hong Kong, France and 5 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Biperiden in India?

1 supplier in India list Biperiden on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Biperiden?

Suppliers quote Biperiden on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Biperiden

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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