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Analgesics and anti-inflammatories

Bromfenac

Also known as 2-(2-Amino-3-(4-bromobenzoyl)phenyl)acetic acid, 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid, Bromfenaco

CAS 91714-94-2Formula C15H12BrNO3Molar mass 334.17 g/mol
19 suppliers listed Drug substance
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Bromfenac chemical structure, C15H12BrNO3, CAS 91714-94-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
91714-94-2
Formula
C15H12BrNO3
Molar mass
334.17 g/mol
HS code
292250
Category
Analgesics and anti-inflammatories

What is Bromfenac?

Plain description, key identifiers and synonyms

Bromfenac is amfenac in which the the hydrogen at the 4 position of the benzoyl group is substituted by bromine. It is used for the management of ocular pain and treatment of postoperative inflammation in patients who have undergone cataract extraction. It was withdrawn from the US market in 1998, following concerns over off-label abuse and hepatic failure. It has a role as a non-steroidal anti-inflammatory drug and a non-narcotic analgesic. It is a member of benzophenones, an aromatic amino acid, an organobromine compound and a substituted aniline. It is functionally related to an amfenac. It is a conjugate acid of a bromfenac(1-).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid
CAS number
91714-94-2 CAS number cross-checkedOther or deprecated CAS: 120638-55-3
Molecular formula
C15H12BrNO3
UNII
864P0921DW
MDL number
MFCD00864341
InChIKey
ZBPLOVFIXSTCRZ-UHFFFAOYSA-N
InChI
InChI=1S/C15H12BrNO3/c16-11-6-4-9(5-7-11)15(20)12-3-1-2-10(14(12)17)8-13(18)19/h1-7H,8,17H2,(H,18,19)
SMILES (canonical and isomeric)
C1=CC(=C(C(=C1)C(=O)C2=CC=C(C=C2)Br)N)CC(=O)O

Synonyms

  • 2-(2-Amino-3-(4-bromobenzoyl)phenyl)acetic acid
  • 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid
  • Bromfenaco
  • Bromfenacum
  • 2-Amino-3-(4-bromobenzoyl)benzeneacetic acid
  • Benzeneacetic acid, 2-amino-3-(4-bromobenzoyl)-
  • [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid
  • 2-{2-amino-3-[(4-bromophenyl)carbonyl]phenyl}acetic acid
  • (2-Amino-3-(4-bromo-benzoyl)-phenyl)-acetic acid
  • 2-(2-amino-3-((4-bromophenyl)carbonyl)phenyl)acetic acid
  • Xibrom
  • [2-amino-3-(4-bromobenzoyl)phenyl]acetic acid
  • Bromfenac (INN)
  • 4mjq
  • AHR 10282
  • Bromfenac sodium hydrate (2:2:3)
  • 2-Amino-3-(4-bromobenzoyl) phenylacetic acid hydrate
  • 2-Amino-3-(4-bromobenzoyl)benzeneacetic Acid Sodium Salt Hydrate

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
334.17 g/molcalc.
Exact mass
333.0001 Dacalc.
LogP (octanol/water)
2.89calc.
Topological polar surface area
80.39 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
4calc.
Heavy atoms
20calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.07calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(c1ccccc1)c1ccccc1

O=C(c1ccccc1)c1ccccc1

2 rings, 14 atoms, the Benzophenone ring system.

5,108 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Bromfenac suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 19 suppliers
19 of 19 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

19 suppliers in 8 countries

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Bromfenac price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Anti-Inflammatory Agents, Non-Steroidal

Roles

  • analgesic
  • anti-inflammatory agent
  • anti-inflammatory drug
  • antirheumatic drug
  • non-narcotic analgesic
  • non-steroidal anti-inflammatory drug
  • ophthalmology drug
  • pharmaceutical

Pharmacology

Bromfenac is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of bromfenac is as a Cyclooxygenase Inhibitor.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Bromfenac is traded under.

HS 2922.50Indicative HS code

Amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function

World exports in 2024
$3.29B
−5.9% vs 2023, imports $3.19B
2019 to 2024
Top exporters
  1. China39.2%
  2. United Kingdom27.1%
  3. India * partner reported4.8%
Top importers
  1. United States20.7%
  2. Germany7.6%
  3. Italy6.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Bromfenac is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Bromfenac, based on the data on this page

What is Bromfenac?

Bromfenac is amfenac in which the the hydrogen at the 4 position of the benzoyl group is substituted by bromine. It is used for the management of ocular pain and treatment of postoperative inflammation in patients who have undergone cataract extraction.

What is the CAS number of Bromfenac?

The CAS registry number of Bromfenac is 91714-94-2. Other or deprecated CAS numbers: 120638-55-3.

What is the molecular formula and weight of Bromfenac?

The molecular formula of Bromfenac is C15H12BrNO3 and its molar mass is 334.17 g/mol.

What is Bromfenac used for?

Known uses and roles of Bromfenac include analgesics and antipyretics in pharmaceuticals, anti-inflammatories in pharmaceuticals, analgesic, anti-inflammatory agent, anti-inflammatory drug and 6 more.

Is Bromfenac hazardous?

No GHS hazard classification for Bromfenac is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Bromfenac?

Bromfenac is usually classified under HS code 292250 (Amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Bromfenac?

CompoundList lists 19 suppliers of Bromfenac in China, Bangladesh, United States, Canada and 4 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Bromfenac in India?

2 suppliers in India list Bromfenac on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Bromfenac?

Suppliers quote Bromfenac on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Bromfenac

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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