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In-can and dry-film biocides

Bronopol

Also known as 2-Bromo-2-nitro-1,3-propanediol, 2-Bromo-2-nitropropane-1,3-diol, Bronosol

CAS 52-51-7Formula C3H6BrNO4Molar mass 199.99 g/molEC 200-143-0
GHS signal word: Danger. Pictograms: Corrosive, Harmful or irritant, Hazardous to the environment 169 suppliers listed Drug substance
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Bronopol chemical structure, C3H6BrNO4, CAS 52-51-7
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
White crystalline powder
Melting point
131.5 °C
Boiling point
151.7 °C
Density
Relative density (water = 1): 1.9
Flash point
167 °C
HS code
290559
Category
In-can and dry-film biocides
UN number
UN 3241
Illustrative photo, off-white crystalline powder in an HDPE jar on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Bronopol?

Plain description, key identifiers and synonyms

Bronopol is a nitro compound.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-bromo-2-nitropropane-1,3-diol
CAS number
52-51-7 CAS number cross-checked
EC number
200-143-0
Molecular formula
C3H6BrNO4
UNII
6PU1E16C9W
MDL number
MFCD00007390
INCI name
2-BROMO-2-NITROPROPANE-1,3-DIOL
InChIKey
LVDKZNITIUWNER-UHFFFAOYSA-N
InChI
InChI=1S/C3H6BrNO4/c4-3(1-6,2-7)5(8)9/h6-7H,1-2H2
SMILES (canonical and isomeric)
C(C(CO)([N+](=O)[O-])Br)O

Synonyms

  • 2-Bromo-2-nitro-1,3-propanediol
  • 2-Bromo-2-nitropropane-1,3-diol
  • Bronosol
  • Bronocot
  • Bronotak
  • Bronidiol
  • Bronopolu
  • Lexgard bronopol
  • Onyxide 500
  • Bronopolum
  • 1,3-Propanediol, 2-bromo-2-nitro-
  • 2-Nitro-2-bromo-1,3-propanediol
  • beta-Bromo-beta-nitrotrimethyleneglycol
  • 2-bromo-2-nitro-propane-1,3-diol
  • 2-Bromo-2-nitropropan-1,3-diol
  • Remain Silver
  • Remain Gold
  • Gold-Bloc
  • Soft Tuch
  • Gil Sani-Guard
  • Bronopol Teat Dip
  • QM Gold
  • Medic Booster Barrier
  • Ultra-soft barrier dip
  • AST Inc. PRO-4 BARRIER TEAT DIP
Show all 35 synonyms
  • AST Inc. PRO-4 SANITIZING TEAT DIP
  • Sfp inc. td-44 sanitizing teat dip
  • Sfp inc. td-44 barrier sanitizing post teat dip
  • BNPD
  • C3H6BrNO4
  • Bioban
  • Myacide AS plus
  • Myacide BT
  • Myacide Pharma BP
  • Canguard 409

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
White crystalline powderexp.
Odour
Odorlessexp.
Melting point
131.5 °Cexp.
Boiling point
151.7 °Cexp.
Density
Relative density (water = 1): 1.9exp.
Flash point
167 °Cexp.
Solubility
In water, 2.5 × 10⁺⁵ mg/L at 22 °Cexp.
Vapour pressure
1.26 × 10⁻⁵ mm Hg at 20 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
199.99 g/molcalc.
Exact mass
198.948 Dacalc.
LogP (octanol/water)
-0.66calc.
Topological polar surface area
83.6 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
3calc.
Heavy atoms
9calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive
GHS07: Harmful or irritant
Harmful or irritant
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H302Harmful if swallowed.
  • H312Harmful in contact with skin.
  • H315Causes skin irritation.
  • H318Causes serious eye damage.
  • H335May cause respiratory irritation.
  • H400Very toxic to aquatic life.
Precautionary statements (21)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 3241
Transport hazard class
4.1
Packing group
III

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Bronopol suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 169 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

169 suppliers in 17 countries

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Bronopol price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

For seed treatment on cotton for Xanthomonas campestris (blackarm diseae).

Biocide used in recirculating cooling towers.

FDA (1998) approved the use of (bronopol) in adhesives as a component of articles intended for use in packaging, transporting, or holding food...

Industrial uses: Anti-adhesive/cohesive, Preservative, Pigment.

Consumer uses: Anti-adhesive/cohesive, Pigment, Preservative.

Use classes: Cosmetics.

Cosmetic ingredient, INCI name 2-BROMO-2-NITROPROPANE-1,3-DIOL(preservative)

Pharmacological actions

  • Anti-Infective Agents
  • Anti-Infective Agents, Local
  • Indicators and Reagents

Functional uses

  • Biocide
  • Deodorizer
  • Preservative
  • Processing aids not otherwise specified

Cosmetic functions

  • Preservative

Pharmacology

Bronopol is a Standardized Chemical Allergen. The physiologic effect of bronopol is by means of Increased Histamine Release and Cell-mediated Immunity.

How it is made

Bronopol is made by the bromination of the sodium salt of 2-nitropropane-1,3-diol.

Regulatory status

Inventories, regulations and trade controls that list this substance

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 603-085-00-8

Health and food

  • EU cosmetic ingredient inventory
  • EU Cosmetics Regulation Annex V, allowed preservative
    Name: 2-BROMO-2-NITROPROPANE-1,3-DIOL, Ref no: 21, Annex ref: V/21
  • Active ingredient in FDA approved drug labels

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Bronopol is traded under.

HS 2905.59Indicative HS code

Halogenated, sulphonated, nitrated or nitrosated derivatives of acyclic alcohols, other

World exports in 2024
$210M
+1.6% vs 2023, imports $201M
2019 to 2024
Top exporters
  1. China43.9%
  2. Germany11.6%
  3. Spain6.9%
Top importers
  1. Germany17.1%
  2. United States13.4%
  3. India * partner reported12.4%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Bronopol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Bronopol, based on the data on this page

What is Bronopol?

Bronopol is a nitro compound.

What is the CAS number of Bronopol?

The CAS registry number of Bronopol is 52-51-7.

What is the molecular formula and weight of Bronopol?

The molecular formula of Bronopol is C3H6BrNO4 and its molar mass is 199.99 g/mol.

What is Bronopol used for?

For seed treatment on cotton for Xanthomonas campestris (blackarm diseae). Biocide used in recirculating cooling towers. FDA (1998) approved the use of (bronopol) in adhesives as a component of articles intended for use in packaging, transporting, or holding food...

Is Bronopol hazardous?

Bronopol carries the GHS signal word "Danger". Main hazards: harmful if swallowed, harmful in contact with skin, causes skin irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Bronopol?

Bronopol is usually classified under HS code 290559 (Halogenated, sulphonated, nitrated or nitrosated derivatives of acyclic alcohols, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Bronopol?

CompoundList lists 169 suppliers of Bronopol in China, India, United States, Japan and 13 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Bronopol in India?

43 suppliers in India list Bronopol on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Bronopol?

Suppliers quote Bronopol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Bronopol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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