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Respiratory, allergy and digestive drugs

Carbinoxamine

Also known as Paracarbinoxamine, Allergefon, Carbinoxamina

CAS 486-16-8Formula C16H19ClN2OMolar mass 290.79 g/molEC 207-628-6
11 suppliers listed Drug substance
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Carbinoxamine chemical structure, C16H19ClN2O, CAS 486-16-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
486-16-8
Formula
C16H19ClN2O
Molar mass
290.79 g/mol
EC number
207-628-6
HS code
293339
Category
Respiratory, allergy and digestive drugs

What is Carbinoxamine?

Plain description, key identifiers and synonyms

Carbinoxamine is an organochlorine compound that is 2-(4-chlorobenzyl)pyridine in which one of the benzylic hydrogens is substituted by 2-(dimethylamino)ethoxy group. It is an ethanolamine-type antihistamine, used as its maleate salt for treating hay fever, as well as mild cases of Parkinson's disease. It has a role as a H1-receptor antagonist, an antiparkinson drug, a muscarinic antagonist and an anti-allergic agent. It is a member of pyridines, a tertiary amino compound and a member of monochlorobenzenes.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-[(4-chlorophenyl)-pyridin-2-ylmethoxy]-N,N-dimethylethanamine
CAS number
486-16-8 CAS number cross-checked
EC number
207-628-6
Molecular formula
C16H19ClN2O
UNII
982A7M02H5
MDL number
MFCD00137402
InChIKey
OJFSXZCBGQGRNV-UHFFFAOYSA-N
InChI
InChI=1S/C16H19ClN2O/c1-19(2)11-12-20-16(15-5-3-4-10-18-15)13-6-8-14(17)9-7-13/h3-10,16H,11-12H2,1-2H3
SMILES (canonical and isomeric)
CN(C)CCOC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2

Synonyms

  • Paracarbinoxamine
  • Allergefon
  • Carbinoxamina
  • Carbinoxaminum
  • (+-)-Carbinoxamine
  • Carbinoxamine base
  • Palgic
  • 2-(p-Chloro-alpha-(2-(dimethylamino)ethoxy)benzyl)pyridine
  • Ethanamine, 2-((4-chlorophenyl)-2-pyridinylmethoxy)-N,N-dimethyl-
  • Ethanamine, 2-[(4-chlorophenyl)-2-pyridinylmethoxy]-N,N-dimethyl-
  • N,N-Dimethyl-2-(p-chloro-alpha-(2-pyridyl)benzyloxy)ethylamine
  • Arbinoxa
  • {2-[(4-chlorophenyl)(pyridin-2-yl)methoxy]ethyl}dimethylamine
  • {2-[(4-Chloro-phenyl)-pyridin-2-yl-methoxy]-ethyl}-dimethyl-amine
  • (2-((4-chlorophenyl)(pyridin-2-yl)methoxy)ethyl)dimethylamine
  • (2-((4-Chloro-phenyl)-pyridin-2-yl-methoxy)-ethyl)-dimethyl-amine
  • Paracarinoxamine
  • 2-((4-Chlorophenyl)(pyridin-2-yl)methoxy)-N,N-dimethylethanamine
  • McN-R 73Z
  • 2-[(4-chlorophenyl)-pyridin-2-ylmethoxy]-N,N-dimethylethanamine
  • Carbinoxamine-d6 Maleate Salt
  • Carbinoxamine (INN)
  • (+/-)-carbinoxamine
  • {2-[(4-chlorophenyl)(pyridin-2-yl)methoxy]ethyl}dimethylamine maleate
  • {2-[(4-Chlorophenyl)-2-pyridylmethoxy]ethyl}dimethylamine
Show all 32 synonyms
  • 2-[(4-chlorophenyl)(pyridin-2-yl)methoxy]-N,N-dimethylethanamine
  • ( inverted exclamation markA)-Carbinoxamine
  • 2-[(4-chlorophenyl)-(2-pyridyl)methoxy]-N,N-dimethyl-ethanamine
  • Carbinoxamine, McN-R 73Z, Paracarbinoxamine, Paracarinoxamine
  • 2-((4-chlorophenyl)(pyridin-2-yl)methoxy)-N,N-dimethylethan-1-amine
  • 2-[(4-chlorophenyl)-pyridin-2-yl-methoxy]-N,N-dimethyl-ethanamine
  • 2-[(4-chlorophenyl)(pyridin-2-yl)methoxy]-N,N-dimethylethanamine maleate

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
290.79 g/molcalc.
Exact mass
290.1186 Dacalc.
LogP (octanol/water)
3.4calc.
Topological polar surface area
25.36 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
6calc.
Heavy atoms
20calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.31calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(Cc2ccccn2)cc1

c1ccc(Cc2ccccn2)cc1

2 rings, 13 atoms, the 2-(Phenylmethyl)pyridine ring system.

671 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Carbinoxamine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 11 suppliers
11 of 11 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

11 suppliers in 6 countries

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Carbinoxamine price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Histamine H1 Antagonists

Roles

  • H1-receptor antagonist
  • antagonist
  • anti-allergic agent
  • antidyskinesia agent
  • antiparkinson drug
  • cholinergic antagonist
  • cholinergic drug
  • histamine antagonist
  • histaminergic drug
  • muscarinic antagonist
  • neurotransmitter agent
  • pharmaceutical

Pharmacology

Carbinoxamine is a Histamine-1 Receptor Antagonist. The mechanism of action of carbinoxamine is as a Histamine H1 Receptor Antagonist.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Carbinoxamine is traded under.

HS 2933.39Indicative HS code

Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure…

World exports in 2024
$9.16B
−17.9% vs 2023, imports $10.6B
2019 to 2024
Top exporters
  1. China21.5%
  2. India * partner reported12.3%
  3. Ireland11.6%
Top importers
  1. Germany14.2%
  2. United States12.8%
  3. Brazil10.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Carbinoxamine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Carbinoxamine, based on the data on this page

What is Carbinoxamine?

Carbinoxamine is an organochlorine compound that is 2-(4-chlorobenzyl)pyridine in which one of the benzylic hydrogens is substituted by 2-(dimethylamino)ethoxy group. It is an ethanolamine-type antihistamine, used as its maleate salt for treating hay fever, as well as mild cases of Parkinson's disease.

What is the CAS number of Carbinoxamine?

The CAS registry number of Carbinoxamine is 486-16-8.

What is the molecular formula and weight of Carbinoxamine?

The molecular formula of Carbinoxamine is C16H19ClN2O and its molar mass is 290.79 g/mol.

What is Carbinoxamine used for?

Use classes: Pharmaceuticals.

Is Carbinoxamine hazardous?

No GHS hazard classification for Carbinoxamine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Carbinoxamine?

Carbinoxamine is usually classified under HS code 293339 (Compounds containing an unfused pyridine ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Carbinoxamine?

CompoundList lists 11 suppliers of Carbinoxamine in India, China, Canada, Hong Kong and 2 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Carbinoxamine in India?

5 suppliers in India list Carbinoxamine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Carbinoxamine?

Suppliers quote Carbinoxamine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Carbinoxamine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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