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Synthetic aroma chemicals

Carvacrol

Also known as 5-Isopropyl-2-methylphenol, Isopropyl-o-cresol, Antioxine

CAS 499-75-2Formula C10H14OMolar mass 150.22 g/molEC 207-889-6
GHS signal word: Warning. Pictograms: Harmful or irritant 131 suppliers listed
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Carvacrol chemical structure, C10H14O, CAS 499-75-2
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Needles
Melting point
1 °C
Boiling point
237 to 238
Density
0.976 @ 20 °C/4 °C
Flash point
100 °C
HS code
290719
Category
Synthetic aroma chemicals
Illustrative photo, closed white HDPE bottles and amber jars on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Carvacrol?

Plain description, key identifiers and synonyms

Carvacrol is a phenol that is a natural monoterpene derivative of cymene. An inhibitor of bacterial growth, it is used as a food additive. Potent activator of the human ion channels transient receptor potential V3 (TRPV3) and A1 (TRPA1). It has a role as a TRPA1 channel agonist, a volatile oil component, an antimicrobial agent, an agrochemical and a flavouring agent. It is a p-menthane monoterpenoid, a member of phenols and a botanical anti-fungal agent. It derives from a hydride of a p-cymene.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-methyl-5-propan-2-ylphenol
CAS number
499-75-2 CAS number cross-checked
EC number
207-889-6
Molecular formula
C10H14O
UNII
9B1J4V995Q
MDL number
MFCD00002236
INCI name
CARVACROL
InChIKey
RECUKUPTGUEGMW-UHFFFAOYSA-N
InChI
InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)10(11)6-9/h4-7,11H,1-3H3
SMILES (canonical and isomeric)
CC1=C(C=C(C=C1)C(C)C)O

Synonyms

  • 5-Isopropyl-2-methylphenol
  • Isopropyl-o-cresol
  • Antioxine
  • 2-p-Cymenol
  • 5-Isopropyl-o-cresol
  • 2-Hydroxy-p-cymene
  • Phenol, 2-methyl-5-(1-methylethyl)-
  • Karvakrol
  • p-Cymen-2-ol
  • 2-Methyl-5-isopropylphenol
  • 2-methyl-5-propan-2-ylphenol
  • 3-Isopropyl-6-methylphenol
  • p-Cymene, 2-hydroxy-
  • 1-Hydroxy-2-methyl-5-isopropylbenzene
  • Phenol, 5-isopropyl-2-methyl-
  • 1-Methyl-2-hydroxy-4-isopropylbenzene
  • Dentol
  • o-Thymol
  • 2-Methyl-5-(1-methylethyl)phenol
  • 5-Isopropyl-2-methyl-phenol
  • 2-Methyl-5-(Propan-2-Yl)Phenol
  • 6-Methyl-3-isopropylphenol
  • o-Cresol, 5-isopropyl-
  • Cymophenol
  • Oxycymol
Show all 38 synonyms
  • Phenol, 3-isopropyl-6-methyl-
  • 2-Methyl-5-(1-methylethyl)-Phenol
  • 2-methyl-5-propan-2-yl-phenol
  • 2-methyl-5-(methylethyl)phenol
  • Cymene-2-ol, p-
  • 2-Hydroxy-4-(2-propyl)toluene
  • Cymenol
  • 2-Hydroxycymene
  • cis-carvacrol
  • Hydroxy-p-cymene
  • p-Cymene-2-ol
  • Carvacrol, 98%
  • Carvacrol (Standard)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Needlesexp.
Odour
THYMOL ODORexp.
Taste
EXCELLENT SMOKE TASTE, @ 1-5 PPMexp.
Melting point
1 °Cexp.
Boiling point
237 to 238exp.
Density
0.976 @ 20 °C/4 °Cexp.
Flash point
100 °Cexp.
Solubility
SLIGHTLY SOL IN WATER, SOL IN ETHANOL, ETHER, ALKALIS, VERY SOLUBLE IN ACETONEexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
150.22 g/molcalc.
Exact mass
150.1045 Dacalc.
LogP (octanol/water)
2.82calc.
Topological polar surface area
20.23 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
1calc.
Heavy atoms
11calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.4calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H315Causes skin irritation.
  • H317May cause an allergic skin reaction.
  • H319Causes serious eye irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Carvacrol suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 131 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

131 suppliers in 15 countries

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Carvacrol price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Disinfectant, in organic syntheses.

Medication: antifungal, anthelmintic agent.

Perfumes, flavoring.

Cosmetic ingredient, INCI name CARVACROL(perfuming)

Roles

  • TRPA1 channel agonist
  • additive
  • agonist
  • agrochemical
  • antimicrobial agent
  • eukaryotic metabolite
  • flavouring agent
  • food additive
  • food component
  • metabolite
  • physiological role
  • plant metabolite
  • volatile oil component

Functional uses

  • Flavouring and nutrient
  • Fragrance

Cosmetic functions

  • Perfuming

How it is made

From p-cymene by sulfonation & subsequent alkali fusion. Hixson & mckee, chem zentr, II: 851, 1919, gibbs & phillips, j ind eng chem, 12: 145, 1920.

By chlorination of alpha-pinene with tert-butyl hypochlorite: ritter, ginsburg, j am chem soc 72, 2381 (1950), from 2-bromo-p-cymol: strubell, baumgartel, arch pharm 291, 66 (1958).

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Carvacrol is traded under.

HS 2907.19Indicative HS code

Monophenols, other

World exports in 2024
$671M
+2.2% vs 2023, imports $781M
2019 to 2024
Top exporters
  1. China20.1%
  2. Germany14.4%
  3. Switzerland * partner reported11.1%
Top importers
  1. China16.3%
  2. Germany10.1%
  3. South Korea8.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Carvacrol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Carvacrol, based on the data on this page

What is Carvacrol?

Carvacrol is a phenol that is a natural monoterpene derivative of cymene. An inhibitor of bacterial growth, it is used as a food additive. Potent activator of the human ion channels transient receptor potential V3 (TRPV3) and A1 (TRPA1).

What is the CAS number of Carvacrol?

The CAS registry number of Carvacrol is 499-75-2.

What is the molecular formula and weight of Carvacrol?

The molecular formula of Carvacrol is C10H14O and its molar mass is 150.22 g/mol.

What is Carvacrol used for?

Disinfectant, in organic syntheses. Medication: antifungal, anthelmintic agent. Perfumes, flavoring.

Is Carvacrol hazardous?

Carvacrol carries the GHS signal word "Warning". Main hazards: harmful if swallowed, causes skin irritation, may cause an allergic skin reaction. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Carvacrol?

Carvacrol is usually classified under HS code 290719 (Monophenols, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Carvacrol?

CompoundList lists 131 suppliers of Carvacrol in China, United States, India, Germany and 11 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Carvacrol in India?

11 suppliers in India list Carvacrol on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Carvacrol?

Suppliers quote Carvacrol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Carvacrol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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