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Nucleosides and nucleotides

Cgmp

Also known as cyclic gmp, Cyclic guanosine monophosphate, 3',5'-cyclic GMP

CAS 7665-99-8Formula C10H12N5O7PMolar mass 345.21 g/molEC 231-641-6
GHS signal word: Warning. Pictograms: Harmful or irritant 45 suppliers listed
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Cgmp chemical structure, C10H12N5O7P, CAS 7665-99-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
7665-99-8
Formula
C10H12N5O7P
Molar mass
345.21 g/mol
EC number
231-641-6
HS code
293499
Category
Nucleosides and nucleotides

What is Cgmp?

Plain description, key identifiers and synonyms

3',5'-cyclic GMP is a 3',5'-cyclic purine nucleotide in which the purine nucleobase is specified as guanidine. It has a role as a mouse metabolite, a Saccharomyces cerevisiae metabolite, a plant metabolite, an Escherichia coli metabolite and a human metabolite. It is a 3',5'-cyclic purine nucleotide and a guanyl ribonucleotide. It is a conjugate acid of a 3',5'-cyclic GMP(1-).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-amino-1H-purin-6-one
CAS number
7665-99-8 CAS number cross-checked
EC number
231-641-6
Molecular formula
C10H12N5O7P
UNII
H2D2X058MU
MDL number
MFCD00070129
InChIKey
ZOOGRGPOEVQQDX-UUOKFMHZSA-N
InChI
InChI=1S/C10H12N5O7P/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17)/t3-,5-,6-,9-/m1/s1
Canonical SMILES
Nc1nc2c(ncn2C2OC3COP(=O)(O)OC3C2O)c(=O)[nH]1
Isomeric SMILES
C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C3N=C(NC4=O)N)O)OP(=O)(O1)O

Synonyms

  • cyclic gmp
  • Cyclic guanosine monophosphate
  • 3',5'-cyclic GMP
  • Guanosine 3',5'-cyclic monophosphate
  • Guanosine cyclic monophosphate
  • guanosine 3',5'-cyclic phosphate
  • Guanosine 3',5'-phosphate
  • Guanosine, cyclic 3',5'-(hydrogen phosphate)
  • Guanosine cyclic 3',5'-monophosphate
  • cyclic 3',5'-guanosine monophosphate
  • 9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-amino-1H-purin-6-one
  • GMP, Cyclic
  • 9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-amino-3H-purin-6-one
  • 9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-hexahydro-2lambda5-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-amino-6,9-dihydro-1H-purin-6-one
  • Cyclic Monophosphate, Guanosine
  • Monophosphate, Guanosine Cyclic
  • 2-amino-9-((1S,6R,8R,9R)-3,9-dihydroxy-3-oxo-2,4,7-trioxa-3$l^(5)-phosphabicyclo(4.3.0)nonan-8-yl)-3H-purin-6-one
  • 2-amino-9-[(1S,6R,8R,9R)-3,9-dihydroxy-3-oxo-2,4,7-trioxa-3$l^{5}-phosphabicyclo[4.3.0]nonan-8-yl]-3H-purin-6-one
  • 9-((4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo(3,2-d)(1,3,2)dioxaphosphinin-6-yl)-2-amino-1H-purin-6-one
  • 9-((4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo(3,2-d)(1,3,2)dioxaphosphinin-6-yl)-2-amino-3H-purin-6-one
  • 9-((4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-hexahydro-1,3,5,2$l^(5)-furo(3,2-d)(1,3,2$l^(5))dioxaphosphinin-6-yl)-2-amino-6,9-dihydro-1H-purin-6-one
  • 9-((4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-hexahydro-2lambda5-furo(3,2-d)(1,3,2)dioxaphosphinin-6-yl)-2-amino-6,9-dihydro-1H-purin-6-one
  • 9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-hexahydro-1,3,5,2$l^{5}-furo[3,2-d][1,3,2$l^{5}]dioxaphosphinin-6-yl]-2-amino-6,9-dihydro-1H-purin-6-one
  • Guanosine Cyclic 3,5 Monophosphate
  • Guanosine Cyclic 3',5' Monophosphate
Show all 38 synonyms
  • Guanosine Cyclic-3',5'-Monophosphate
  • 3',5'-Monophosphate, Guanosine Cyclic
  • Cyclic 3',5'-Monophosphate, Guanosine
  • Cyclic-3',5'-Monophosphate, Guanosine
  • Guanosine 3',5'-monophosphate
  • Cyclic 3',5'-GMP
  • cyclic-GMP
  • Guanosine cyclic 3',5'-phosphate
  • Cyclic guanosine 3',5'-monophosphate
  • Guanosine-3',5'-monophosphate
  • Cyclic 3',5'-guanylic acid
  • 3',5'-guanosine monophosphate
  • guanosine-cyclic-phosphoric-acid

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
345.21 g/molcalc.
Exact mass
345.0474 Dacalc.
LogP (octanol/water)
-1.52calc.
Topological polar surface area
174.8 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
9calc.
Rotatable bonds
1calc.
Heavy atoms
23calc.
Rings
4calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.5calc.
Formal charge
0calc.
Stereocentres
5calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1[nH]cnc2c1ncn2C1CC2O[PH](=O)OCC2O1

O=c1[nH]cnc2c1ncn2C1CC2O[PH](=O)OCC2O1

4 rings, 20 atoms.

36 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Cgmp suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 45 suppliers
30 of 30 offers
  • 10X Chem
    United States, San DiegoUnclaimed profile
    CgmpGrade, purity and minimum order on request
    Price on request
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  • 3WAY Pharm Inc
    China, ShanghaiUnclaimed profile
    CgmpGrade, purity and minimum order on request
    Price on request
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  • A2B Chem LLC
    United States, San DiegoUnclaimed profile
    CgmpGrade, purity and minimum order on request
    Price on request
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  • Aa Blocks LLC
    United States, San DiegoUnclaimed profile
    CgmpGrade, purity and minimum order on request
    Price on request
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  • ABCR GmbH & CO. KG
    GermanyUnclaimed profile
    CgmpGrade, purity and minimum order on request
    Price on request
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  • Accel Scientific S.L.
    Spain, BarcelonaUnclaimed profile
    CgmpGrade, purity and minimum order on request
    Price on request
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  • Accela ChemBio Inc.
    United States, San DiegoUnclaimed profile
    CgmpGrade, purity and minimum order on request
    Price on request
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  • AChemBlock
    United States, HaywardUnclaimed profile
    CgmpGrade, purity and minimum order on request
    Price on request
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  • Achemtek
    United States, WoburnUnclaimed profile
    CgmpGrade, purity and minimum order on request
    Price on request
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  • AHH Chemical co.,ltd
    China, ChangzhouUnclaimed profile
    CgmpGrade, purity and minimum order on request
    Price on request
    View

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

45 suppliers in 10 countries

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Cgmp price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • Escherichia coli metabolite
  • Saccharomyces cerevisiae metabolite
  • animal metabolite
  • bacterial metabolite
  • eukaryotic metabolite
  • fungal metabolite
  • human metabolite
  • mammalian metabolite
  • metabolite
  • mouse metabolite
  • plant metabolite
  • prokaryotic metabolite

Pharmacology

Cyclic GMP is a cellular regulatory agent that acts as a second messenger. Its levels increase in response to a variety of signals (acetylcholine, insulin, oxytocin) and activates specific protein kinases.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Cgmp is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Cgmp is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Cgmp, based on the data on this page

What is Cgmp?

3',5'-cyclic GMP is a 3',5'-cyclic purine nucleotide in which the purine nucleobase is specified as guanidine. It has a role as a mouse metabolite, a Saccharomyces cerevisiae metabolite, a plant metabolite, an Escherichia coli metabolite and a human metabolite.

What is the CAS number of Cgmp?

The CAS registry number of Cgmp is 7665-99-8.

What is the molecular formula and weight of Cgmp?

The molecular formula of Cgmp is C10H12N5O7P and its molar mass is 345.21 g/mol.

What is Cgmp used for?

Known uses and roles of Cgmp include escherichia coli metabolite, saccharomyces cerevisiae metabolite, animal metabolite, bacterial metabolite, eukaryotic metabolite and 7 more.

Is Cgmp hazardous?

Cgmp carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Cgmp?

Cgmp is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Cgmp?

CompoundList lists 45 suppliers of Cgmp in United States, China, Germany, United Kingdom and 6 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Cgmp?

Suppliers quote Cgmp on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Cgmp

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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