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Herbicides

Chloroacetamide

Also known as 2-Chloroacetamide, Acetamide, 2-chloro-, Chloracetamide

CAS 79-07-2Formula C2H4ClNOMolar mass 93.51 g/molEC 201-174-2
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Serious health hazard 27 suppliers listed
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Chloroacetamide chemical structure, C2H4ClNO, CAS 79-07-2
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystals from water
Melting point
119 to 120
Boiling point
Ca. 225
Density
Relative density of the vapour/air-mixture at 20 °C (air = 1): 1.00
Flash point
170 °C
HS code
292419
Category
Herbicides
UN number
UN 2811
Illustrative photo, 25 kg white woven sacks of powder on a pallet in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Chloroacetamide?

Plain description, key identifiers and synonyms

2-chloroacetamide is a monocarboxylic acid amide that is acetamide substituted by a chloro group at position 2. It has a role as an antimicrobial cosmetic preservative, a fungicide, a herbicide and an antimicrobial agent. It is a primary carboxamide, a monocarboxylic acid amide, an organochlorine compound and a N-acylammonia.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-chloroacetamide
CAS number
79-07-2 CAS number cross-checked
EC number
201-174-2
Molecular formula
C2H4ClNO
UNII
2R97846T1L
MDL number
MFCD00008027
INCI name
CHLOROACETAMIDE
InChIKey
VXIVSQZSERGHQP-UHFFFAOYSA-N
InChI
InChI=1S/C2H4ClNO/c3-1-2(4)5/h1H2,(H2,4,5)
SMILES (canonical and isomeric)
C(C(=O)N)Cl

Synonyms

  • 2-Chloroacetamide
  • Acetamide, 2-chloro-
  • Chloracetamide
  • Microcide
  • 2-Chloroethanamide
  • Mergal AF
  • Chloracetamid
  • alpha-Chloroacetamide
  • 2-Chloracetamide
  • USAF DO-29
  • 2-Chloro-acetamide
  • alpha-Chloracetamide
  • a-chloroacetamide
  • monochloroacetamide
  • Chloroacetamide-d4
  • 2--Chloroacetamide
  • Microcide Mergal AF
  • ClCH2CONH2
  • KM 101 (fungicide)
  • 2-chloroacetic acid amide
  • Acetamide, alpha-chloro-
  • 2-Chloroacetamide, >=98%
  • Acetic acid,chloro,amide
  • KM 101
  • 2-Chloroacetamide, >=98.0% (HPLC)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystals from waterexp.
Odour
Characteristic odorexp.
Melting point
119 to 120exp.
Boiling point
Ca. 225exp.
Density
Relative density of the vapour/air-mixture at 20 °C (air = 1): 1.00exp.
Flash point
170 °Cexp.
Solubility
In water, 90,000 mg/L at 25 °Cexp.
Vapour pressure
VP: 0.007 Pa at 20 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
93.51 g/molcalc.
Exact mass
92.9981 Dacalc.
LogP (octanol/water)
-0.29calc.
Topological polar surface area
43.09 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
1calc.
Heavy atoms
5calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.5calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H301Toxic if swallowed.
  • H317May cause an allergic skin reaction.
  • H361fSuspected of damaging fertility.
Precautionary statements (15)
  • P203Obtain, read and follow all safety instructions before use.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P318If exposed or concerned, get medical advice.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 2811
Transport hazard class
6.1
Packing group
III

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Chloroacetamide suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 27 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

27 suppliers in 9 countries

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Chloroacetamide price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Intermediate.

Chloroacetamide is a versatile intermediate. In addition, it has biocidal properties and, therefore, is used as an industrial preservative. Because of its good solubility in water, chloroacetamide is a particularly suitable biocide for protection of the aqueous phase, ... in water-containing paints, and as a wood preservative. Its insecticidal action on aphids and its use as a hardener for urea and melamine resins have also been described.

Former use: Chloroacetamide is used as a preservative and antiseptic in cosmetics. Its function is to retard the deterioration of cosmetic products by slowing the growth of bacteria or fungi.

Chloracetamide is used as a preservative for emulsions, cutting oils, hides, and paintings.

Intermediate in the production of herbicides and insecticides.

Use classes: Cosmetics.

Cosmetic ingredient, INCI name CHLOROACETAMIDE(preservative)

Roles

  • antifungal agent
  • antimicrobial agent
  • antimicrobial cosmetic preservative
  • fungicide
  • herbicide
  • pesticide

Functional uses

  • Preservative

Cosmetic functions

  • Preservative

Pharmacology

Chloroacetamide is a chlorinated sulfhydryl alkylating reagent that forms covalent bonds with the thiol group of cysteines so the protein or peptide no longer forms disulfide bonds.

How it is made

Prepared from ethyl chloroacetate and ammonia, ... from chloroacetyl chloride and ammonium acetate...

Obtained on an industrial scale by reaction of methylchloroacetate with ammonia at low temperature. Manufacture from chloroacetic acid and cyanamide at 150 to 200 °C also has been described.

Regulatory status

Inventories, regulations and trade controls that list this substance

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 616-036-00-0

Health and food

  • EU cosmetic ingredient inventory
  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: 2-Chloracetamide, Ref no: 1387, Annex ref: II/1387

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Chloroacetamide is traded under.

HS 2924.19Indicative HS code

Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other

World exports in 2024
$2.38B
−1.7% vs 2023, imports $2.22B
2019 to 2024
Top exporters
  1. China34.7%
  2. Germany12.5%
  3. India * partner reported6.8%
Top importers
  1. United States17.5%
  2. Germany8.8%
  3. India * partner reported6.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Chloroacetamide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Chloroacetamide, based on the data on this page

What is Chloroacetamide?

2-chloroacetamide is a monocarboxylic acid amide that is acetamide substituted by a chloro group at position 2. It has a role as an antimicrobial cosmetic preservative, a fungicide, a herbicide and an antimicrobial agent.

What is the CAS number of Chloroacetamide?

The CAS registry number of Chloroacetamide is 79-07-2.

What is the molecular formula and weight of Chloroacetamide?

The molecular formula of Chloroacetamide is C2H4ClNO and its molar mass is 93.51 g/mol.

What is Chloroacetamide used for?

Intermediate. Chloroacetamide is a versatile intermediate. In addition, it has biocidal properties and, therefore, is used as an industrial preservative. Because of its good solubility in water, chloroacetamide is a particularly suitable biocide for protection of the aqueous phase, ...

Is Chloroacetamide hazardous?

Chloroacetamide carries the GHS signal word "Danger". Main hazards: toxic if swallowed, may cause an allergic skin reaction, suspected of damaging fertility. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Chloroacetamide?

Chloroacetamide is usually classified under HS code 292419 (Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Chloroacetamide?

CompoundList lists 27 suppliers of Chloroacetamide in China, United States, India, Canada and 5 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Chloroacetamide in India?

4 suppliers in India list Chloroacetamide on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Chloroacetamide?

Suppliers quote Chloroacetamide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Chloroacetamide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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