Cholesterol
Also known as Cholesterin, Cholest-5-en-3beta-ol, Cholesteryl alcohol
Key facts
What buyers check first
- Appearance
- White or faintly yellow pearly granules or crystals
- Melting point
- 148.5 °C
- Boiling point
- 360 °C
- Density
- 1.067 @ 20 °C/4 °C
- Solubility
- In water, 0.095 mg/l @ 30 °C.
- HS code
- 290613
- Category
- Steroids and sterols

What is Cholesterol?
Plain description, key identifiers and synonyms
Cholesterol is a cholestanoid consisting of cholestane having a double bond at the 5,6-position as well as a 3beta-hydroxy group. It has a role as a mouse metabolite, a human metabolite, a Daphnia galeata metabolite and an algal metabolite. It is a C27-steroid, a 3beta-hydroxy-Delta(5)-steroid, a 3beta-sterol and a cholestanoid.
Cholesterol is a sterol biosynthesized by all animal cells which is an essential structural component of all animal cell membranes.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
- CAS number
- 57-88-5 CAS number cross-checkedOther or deprecated CAS: 129111-15-5, 22243-67-0, 80356-14-5
- EC number
- 200-353-2
- Molecular formula
- C27H46O
- UNII
- 97C5T2UQ7J
- MDL number
- MFCD00003646
- INCI name
- CHOLESTEROL
- InChIKey
- HVYWMOMLDIMFJA-DPAQBDIFSA-N
- InChI
- InChI=1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
- Canonical SMILES
- CC(C)CCCC(C)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C
- Isomeric SMILES
- C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C
Synonyms
- Cholesterin
- Cholest-5-en-3beta-ol
- Cholesteryl alcohol
- Dythol
- Cordulan
- Dusoline
- Dusoran
- Cholesterine
- Cholestrin
- Cholestrol
- Hydrocerin
- Lidinite
- Kathro
- Lanol
- Super hartolan
- Lidinit
- Cholesterol base H
- Nimco cholesterol base H
- (-)-Cholesterol
- 3beta-Hydroxycholest-5-ene
- Tegolan
- 5:6-Cholesten-3beta-ol
- (3beta)-cholest-5-en-3-ol
- Provitamin-d
- Cholest-5-en-3-ol (3beta)-
Show all 37 synonymsShow fewer synonyms
- (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
- 5-Cholesten-3B-ol
- (3beta,14beta,17alpha)-cholest-5-en-3-ol
- (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((2R)-6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta(a)phenanthren-3-ol
- 10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta(a)phenanthren-3-ol
- 10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
- Cholesterol 1551
- (1S,2R,10S,11S,14R,15R)-2,15-dimethyl-14-((2R)-6-methylheptan-2-yl)tetracyclo(8.7.0.02,7.011,15)heptadec-7-en-5-ol
- Cholesterinum
- Tegolan (VAN)
- Cholest-5-en-3-beta-ol
- 3-beta-Hydroxycholest-5-ene
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | White or faintly yellow pearly granules or crystalsexp.Measured value |
|---|---|
| Odour | Almost odorlessexp.Measured value |
| Melting point | 148.5 °Cexp.Measured value |
| Boiling point | 360 °Cexp.Measured value |
| Density | 1.067 @ 20 °C/4 °Cexp.Measured value |
| Solubility | In water, 0.095 mg/l @ 30 °C.exp.Measured value |
| Vapour pressure | VP: 0.171 mm Hg at 149 °Cexp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 386.66 g/molcalc.Computed value |
|---|---|
| Exact mass | 386.3549 Dacalc.Computed value |
| LogP (octanol/water) | 7.39calc.Computed value |
| Topological polar surface area | 20.23 Ųcalc.Computed value |
| Hydrogen bond donors | 1calc.Computed value |
| Hydrogen bond acceptors | 1calc.Computed value |
| Rotatable bonds | 5calc.Computed value |
| Heavy atoms | 28calc.Computed value |
| Rings | 4calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 0.93calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 8calc.Computed value |
| Lipinski rule of five | Passes (1 violation)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Cholesterol suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- ChinaUnclaimed profileCholesterolGrade, purity and minimum order on requestPrice on request
- ChinaUnclaimed profileCholesterolGrade, purity and minimum order on requestPrice on request
- China, ChangzhouUnclaimed profileCholesterolGrade, purity and minimum order on requestPrice on request
- China, SuzhouUnclaimed profileCholesterolGrade, purity and minimum order on requestPrice on request
- Price on request
- India, Vadodara ManufacturerUnclaimed profileCholesterolGrade, purity and minimum order on requestPrice on request
- China, BeijingUnclaimed profileCholesterolGrade, purity and minimum order on requestPrice on request
- China ManufacturerUnclaimed profileCholesterolGrade, purity and minimum order on requestPrice on request
- China, Changzhou ManufacturerUnclaimed profileCholesterolGrade, purity and minimum order on requestPrice on request
- China, Changzhou ManufacturerUnclaimed profileCholesterolGrade, purity and minimum order on requestPrice on request
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Where suppliers are based
178 suppliers in 28 countries
- China59
- United States41
- India16
- Germany6
- United Kingdom5
- Italy5
- and 22 more countries
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Cholesterol price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Used in pharmaceutical and dermal preparations as an emulsifying agent.
Important as raw material for syntheses involving microbiological degradation of the side chain.
Use classes: Cosmetics.
Industries and functions
Cosmetic ingredient, INCI name CHOLESTEROL(skin conditioning - emollient, surfactant - emulsifying, skin conditioning, light stabilizer)
Roles
- Daphnia galeata metabolite
- Daphnia metabolite
- algal metabolite
- animal metabolite
- antineoplastic agent
- crustacean metabolite
- eukaryotic metabolite
- human metabolite
- mammalian metabolite
- metabolite
- mouse metabolite
- pharmaceutical
Functional uses
- Emulsifier
- Fragrance
- Pharmaceutical
- Processing aids not otherwise specified
- Softener and conditioner
- Stabilizing agent
- Thickening agent
- Viscosity modifier
Cosmetic functions
- Light stabilizer
- Skin conditioning
- Skin conditioning - emollient
- Surfactant - emulsifying
- Viscosity controlling
Pharmacology
Cholesterol is an animal sterol found in the body tissues (and blood plasma) of vertebrates. It can be found in large concentrations within the liver, spinal cord, and brain. Cholesterol is an important component of the membranes of cells, providing stability. It is the major precursor for the synthesis of vitamin D, of the various steroid hormones, including cortisol, cortisone, and aldosterone in the adrenal glands, and of the sex hormones progesterone, estrogen, and testosterone. Cholesterol also has an important role for the brain synapses as well as in the immune system.
Read more
In conditions featuring elevated low density lipoproteins (LDL), cholesterol often forms plaque deposits in the walls of arteries, a condition known as atherosclerosis, which is a major contributor to coronary heart disease and other forms of cardiovascular disease.
How it is made
Prepared commercially from the spinal cord of cattle by petroleum ether extraction of the nonsaponifiable matter. Also produced from wool grease.
Cholesterol is commercially prepared from bovine spinal cord and wool grease by extraction with petroleum ether. The extracted material is then purified by repeated bromination.
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- EU cosmetic ingredient inventory
- Active ingredient in FDA approved drug labels
United States
- TSCA inventory (USA)Status: Active in US commerce
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Cholesterol is traded under.
Sterols and inositols
- China42.0%
- United States16.4%
- Netherlands9.6%
- Ecuador * partner reported13.0%
- China13.0%
- United States9.4%
* Partner reported figures, a lower bound.
The HS code shown for Cholesterol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Cholesterol, based on the data on this page
What is Cholesterol?
What is the CAS number of Cholesterol?
What is the molecular formula and weight of Cholesterol?
What is Cholesterol used for?
Is Cholesterol hazardous?
What is the HS code of Cholesterol?
Where can I buy Cholesterol?
Where can I buy Cholesterol in India?
What is the price of Cholesterol?
Guides for buyers
Practical guides that help when you source, ship or handle Cholesterol
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
- Guide, Trade and logisticsHS codes for chemicals and why they matterHow the Harmonized System classifies chemicals, the chapters that matter, the rules for chemically defined compounds and mixtures, and practical steps to find the right code.Read
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