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Chromotropic acid

Also known as 4,5-dihydroxynaphthalene-2,7-disulfonic acid, 2,7-Naphthalenedisulfonic acid, 4,5-dihydroxy-, 4,5-Dihydroxy-2,7-naphthalenedisulfonic acid

Chromotropic acid chemical structure, C10H8O8S2, CAS 148-25-4
2D chemical structure

Key facts

What buyers check first

CAS number
148-25-4
Formula
C10H8O8S2
Molar mass
320.30 g/mol
EC number
205-712-7
HS code
290899
Category
Dye intermediates

What is Chromotropic acid?

Plain description, key identifiers and synonyms

Chromotropic acid is a naphthalenesulfonic acid that is naphthalene-2,7-disulfonic acid substituted by hydroxy groups at positions 4 and 5. It has a role as an indicator. It is a member of naphthalenediols and a naphthalenesulfonic acid.

Chromotropic acid is a fluorescent reagent used in analytical chemistry.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4,5-dihydroxynaphthalene-2,7-disulfonic acid
CAS number
148-25-4 CAS number cross-checked
EC number
205-712-7
Molecular formula
C10H8O8S2
UNII
S596OD720M
MDL number
MFCD00003968
InChIKey
HLVXFWDLRHCZEI-UHFFFAOYSA-N
InChI
InChI=1S/C10H8O8S2/c11-8-3-6(19(13,14)15)1-5-2-7(20(16,17)18)4-9(12)10(5)8/h1-4,11-12H,(H,13,14,15)(H,16,17,18)
SMILES (canonical and isomeric)
C1=C2C=C(C=C(C2=C(C=C1S(=O)(=O)O)O)O)S(=O)(=O)O

Synonyms

  • 4,5-dihydroxynaphthalene-2,7-disulfonic acid
  • 2,7-Naphthalenedisulfonic acid, 4,5-dihydroxy-
  • 4,5-Dihydroxy-2,7-naphthalenedisulfonic acid
  • C.I. 16655
  • 4,5-DHN-2,7-DSA
  • 1,8-Dihydroxynaphthylene-3,6-disulfonic acid
  • 4,5-Dihydroxynaphthalene-2,7-disulphonic acid
  • 1,8-dihydroxynaphthalene-3,6-disulfonic acid
  • 4,5-dihydroxynaphthalene-2,7-disulfonicacid
  • doi:10.14272/HLVXFWDLRHCZEI-UHFFFAOYSA-N.1

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
320.30 g/molcalc.
Exact mass
319.9661 Dacalc.
LogP (octanol/water)
0.74calc.
Topological polar surface area
149.2 ร…ยฒcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
2calc.
Heavy atoms
20calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2ccccc2c1

c1ccc2ccccc2c1

2 rings, 10 atoms, the Naphthalene ring system.

17,920 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Chromotropic acid suppliers

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Chromotropic acid price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • indicator

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Chromotropic acid is traded under.

HS 2908.99Indicative HS code

Halogenated, sulphonated, nitrated or nitrosated derivatives of phenols orโ€ฆ

World exports in 2024
$77.7M
+4.6% vs 2023, imports $83.7M
2019 to 2024
Top exporters
  1. China32.2%
  2. India * partner reported22.2%
  3. Spain8.5%
Top importers
  1. United States13.9%
  2. Spain10.6%
  3. Turkey8.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Chromotropic acid is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Chromotropic acid, based on the data on this page

What is Chromotropic acid?

Chromotropic acid is a naphthalenesulfonic acid that is naphthalene-2,7-disulfonic acid substituted by hydroxy groups at positions 4 and 5. It has a role as an indicator. It is a member of naphthalenediols and a naphthalenesulfonic acid.

What is the CAS number of Chromotropic acid?

The CAS registry number of Chromotropic acid is 148-25-4.

What is the molecular formula and weight of Chromotropic acid?

The molecular formula of Chromotropic acid is C10H8O8S2 and its molar mass is 320.30 g/mol.

What is Chromotropic acid used for?

Known uses and roles of Chromotropic acid include indicator.

Is Chromotropic acid hazardous?

Chromotropic acid carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Chromotropic acid?

Chromotropic acid is usually classified under HS code 290899 (Halogenated, sulphonated, nitrated or nitrosated derivatives of phenols orโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Chromotropic acid?

CompoundList lists 18 suppliers of Chromotropic acid in India, China, Hong Kong, Canada and 3 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Chromotropic acid in India?

7 suppliers in India list Chromotropic acid on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Chromotropic acid?

Suppliers quote Chromotropic acid on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Chromotropic acid

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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