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Dyes and pigments

Chrysophanol

Also known as Chrysophanic acid, 1,8-dihydroxy-3-methylanthracene-9,10-dione, 3-Methylchrysazin

CAS 481-74-3Formula C15H10O4Molar mass 254.24 g/molEC 207-572-2
GHS signal word: Warning. Pictograms: Harmful or irritant 61 suppliers listed
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Chrysophanol chemical structure, C15H10O4, CAS 481-74-3
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Yellow hexagonal or monoclinic needles
Melting point
196 °C
Boiling point
Sublimes
Density
0.92 g/cm cu at 25 °C
Solubility
Practically insoluble in water
HS code
291469
Category
Dyes and pigments
Illustrative photo, yellow pigment powder in an open fibre drum in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Chrysophanol?

Plain description, key identifiers and synonyms

Chrysophanol is a trihydroxyanthraquinone that is chrysazin with a methyl substituent at C-3. It has been isolated from Aloe vera and exhibits antiviral and anti-inflammatory activity. It has a role as an antiviral agent, an anti-inflammatory agent and a plant metabolite. It is functionally related to a chrysazin.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1,8-dihydroxy-3-methylanthracene-9,10-dione
CAS number
481-74-3 CAS number cross-checked
EC number
207-572-2
Molecular formula
C15H10O4
UNII
N1ST8V8RR2
MDL number
MFCD00001208
InChIKey
LQGUBLBATBMXHT-UHFFFAOYSA-N
InChI
InChI=1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3
SMILES (canonical and isomeric)
CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3O

Synonyms

  • Chrysophanic acid
  • 1,8-dihydroxy-3-methylanthracene-9,10-dione
  • 3-Methylchrysazin
  • 1,8-Dihydroxy-3-methylanthraquinone
  • 1,8-Dihydroxy-3-methyl-9,10-anthracenedione
  • C.I. Natural Yellow 23
  • 4,5-Dihydroxy-2-methylanthraquinone
  • 3-Methyl-1,8-dihydroxyanthraquinone
  • 2-Methyl-4,5-dihydroxyanthraquinone
  • C.I. 75400
  • 1,8-dihydroxy-3-methyl-9,10-anthraquinone
  • Anthraquinone, 1,8-dihydroxy-3-methyl-
  • Turkey rhubarb
  • Crysophanol
  • Crysophanic acid
  • 1,8-Dihydroxy-3-Methyl-Anthraquinone
  • Rumicin
  • Chrysophanol (Standard)
  • 1,8-dihydroxy-3-methyl-anthracene-9,10-dione
  • 9,10-Anthracenedione, 1,8-dihydroxy-3-methyl-
  • Chrysophanic acid (1,8-dihydroxy-3-methylanthraquinone)
  • 1,8-Dihydroxy-3-methylanthra-9,10-quinone
  • chirysophanol
  • Archinin
  • Chrysophansaeure
Show all 32 synonyms
  • Archinin,
  • Rheic acid,
  • Chrysophanic acid,
  • 3-Methylchrysazin,
  • 4,5-Dihydroxy-
  • Chrysophanic acid (Standard)
  • DivK1c_006417

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Yellow hexagonal or monoclinic needlesexp.
Melting point
196 °Cexp.
Boiling point
Sublimesexp.
Density
0.92 g/cm cu at 25 °Cexp.
Solubility
Practically insoluble in waterexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
254.24 g/molcalc.
Exact mass
254.0579 Dacalc.
LogP (octanol/water)
2.18calc.
Topological polar surface area
74.6 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
0calc.
Heavy atoms
19calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.07calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1c2ccccc2C(=O)c2ccccc21

O=C1c2ccccc2C(=O)c2ccccc21

3 rings, 16 atoms, the Anthraquinone ring system.

2,059 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Chrysophanol suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 61 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

61 suppliers in 8 countries

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Chrysophanol price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Laboratory chemicals, manufacture of substances.

Herbal remedies (Ingredient).

Traditional Medicine (ingredient).

Pharmacological actions

  • Mutagens

Roles

  • anti-inflammatory agent
  • antimicrobial agent
  • antiviral agent
  • eukaryotic metabolite
  • metabolite
  • plant metabolite

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Chrysophanol is traded under.

HS 2914.69Indicative HS code

Quinones, other

World exports in 2024
$162M
−10.1% vs 2023, imports $157M
2019 to 2024
Top exporters
  1. China32.8%
  2. Netherlands29.3%
  3. Japan13.8%
Top importers
  1. United States23.0%
  2. India * partner reported16.1%
  3. Thailand7.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Chrysophanol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Chrysophanol, based on the data on this page

What is Chrysophanol?

Chrysophanol is a trihydroxyanthraquinone that is chrysazin with a methyl substituent at C-3. It has been isolated from Aloe vera and exhibits antiviral and anti-inflammatory activity. It has a role as an antiviral agent, an anti-inflammatory agent and a plant metabolite. It is functionally related to a chrysazin.

What is the CAS number of Chrysophanol?

The CAS registry number of Chrysophanol is 481-74-3.

What is the molecular formula and weight of Chrysophanol?

The molecular formula of Chrysophanol is C15H10O4 and its molar mass is 254.24 g/mol.

What is Chrysophanol used for?

Laboratory chemicals, manufacture of substances. Herbal remedies (Ingredient). Traditional Medicine (ingredient).

Is Chrysophanol hazardous?

Chrysophanol carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Chrysophanol?

Chrysophanol is usually classified under HS code 291469 (Quinones, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Chrysophanol?

CompoundList lists 61 suppliers of Chrysophanol in China, United States, Germany, United Kingdom and 4 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Chrysophanol?

Suppliers quote Chrysophanol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Chrysophanol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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