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Impurities and reference standards

Emodin

Also known as Emodol, Frangula emodin, 1,3,8-trihydroxy-6-methylanthracene-9,10-dione

CAS 518-82-1Formula C15H10O5Molar mass 270.24 g/molEC 208-258-8
GHS signal word: Warning. Pictograms: Harmful or irritant 112 suppliers listed
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Emodin chemical structure, C15H10O5, CAS 518-82-1
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Orange needles from alcohol or by sublimation at 12 mm
Melting point
256 to 257
Boiling point
Sublimes
Solubility
Practically insoluble in water, soluble in alcohol, aqueous alkali hydroxide solutions (…
HS code
291469
Category
Impurities and reference standards
Illustrative photo, drums, an IBC tote and sacks in a chemical warehouse in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Emodin?

Plain description, key identifiers and synonyms

Emodin is a trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor, a laxative and a plant metabolite. It is functionally related to an emodin anthrone. It is a conjugate acid of an emodin(1-).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1,3,8-trihydroxy-6-methylanthracene-9,10-dione
CAS number
518-82-1 CAS number cross-checked
EC number
208-258-8
Molecular formula
C15H10O5
UNII
KA46RNI6HN
MDL number
MFCD00001207
INCI name
EMODIN
InChIKey
RHMXXJGYXNZAPX-UHFFFAOYSA-N
InChI
InChI=1S/C15H10O5/c1-6-2-8-12(10(17)3-6)15(20)13-9(14(8)19)4-7(16)5-11(13)18/h2-5,16-18H,1H3
SMILES (canonical and isomeric)
CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)O

Synonyms

  • Emodol
  • Frangula emodin
  • 1,3,8-trihydroxy-6-methylanthracene-9,10-dione
  • Schuttgelb
  • Rheum emodin
  • Archin
  • Frangulic acid
  • 3-Methyl-1,6,8-trihydroxyanthraquinone
  • Persian Berry Lake
  • 1,3,8-Trihydroxy-6-methylanthraquinone
  • 1,3,8-Trihydroxy-6-methyl-9,10-anthracenedione
  • C.I. Natural Yellow 14
  • 6-Methyl-1,3,8-trihydroxyanthraquinone
  • 9,10-Anthracenedione, 1,3,8-trihydroxy-6-methyl-
  • 1,3,8-Trihydroxy-6-methyl-9,10-anthraquinone
  • 4,5,7-Trihydroxy-2-methylanthraquinone
  • C.I. 75440
  • Anthraquinone, 1,3,8-trihydroxy-6-methyl-
  • 1,3,8-Trihydroxy-6-methylanthra-9,10-quinone
  • Emodin, Rheum
  • Emodin, Frangula
  • 3-Methyl-1,6,8-trihydroxy-antraquinone
  • Alatinone
  • 3bqc
  • Emodin (Standard)
Show all 36 synonyms
  • Diacerein Impurity 1
  • 1f0q
  • Anthraquinone, 6-methyl-1,3,8-trihydroxy-
  • 1,3,8-trihydroxy-6-methyl-9,10-dihydroanthracene-9,10-dione
  • 1,3,8-trihydroxy-6-methyl-anthracene-9,10-dione
  • EMO
  • Anthraquinone,3,8-trihydroxy-6-methyl-
  • 1,3,8-Trihydroxy-6-methyl-anthraquinone
  • 6-Methyl-1,3,8-trihydroxy-9,10-anthracenedione
  • rheum emodium
  • Rheum-emodin

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Orange needles from alcohol or by sublimation at 12 mmexp.
Odour
Orange crystalsexp.
Melting point
256 to 257exp.
Boiling point
Sublimesexp.
Solubility
Practically insoluble in water, soluble in alcohol, aqueous alkali hydroxide solutions (cherry red color), sodium carbonate and ammonia solutions.exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
270.24 g/molcalc.
Exact mass
270.0528 Dacalc.
LogP (octanol/water)
1.89calc.
Topological polar surface area
94.83 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
0calc.
Heavy atoms
20calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.07calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1c2ccccc2C(=O)c2ccccc21

O=C1c2ccccc2C(=O)c2ccccc21

3 rings, 16 atoms, the Anthraquinone ring system.

2,059 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Emodin suppliers

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All 112 suppliers
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Where suppliers are based

112 suppliers in 19 countries

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Emodin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Medicine (cathartic).

This compound is used as a cathartic and a dye intermediate.

Cosmetic ingredient, INCI name EMODIN(skin conditioning)

Pharmacological actions

  • Cathartics
  • Protein Kinase Inhibitors

Roles

  • antineoplastic agent
  • enzyme inhibitor
  • eukaryotic metabolite
  • laxative
  • metabolite
  • pharmaceutical
  • plant metabolite
  • protein kinase inhibitor
  • tyrosine kinase inhibitor

Functional uses

  • Softener and conditioner

Cosmetic functions

  • Skin conditioning

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Emodin is traded under.

HS 2914.69Indicative HS code

Quinones, other

World exports in 2024
$162M
−10.1% vs 2023, imports $157M
2019 to 2024
Top exporters
  1. China32.8%
  2. Netherlands29.3%
  3. Japan13.8%
Top importers
  1. United States23.0%
  2. India * partner reported16.1%
  3. Thailand7.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Emodin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Emodin, based on the data on this page

What is Emodin?

Emodin is a trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens.

What is the CAS number of Emodin?

The CAS registry number of Emodin is 518-82-1.

What is the molecular formula and weight of Emodin?

The molecular formula of Emodin is C15H10O5 and its molar mass is 270.24 g/mol.

What is Emodin used for?

Medicine (cathartic). This compound is used as a cathartic and a dye intermediate.

Is Emodin hazardous?

Emodin carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Emodin?

Emodin is usually classified under HS code 291469 (Quinones, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Emodin?

CompoundList lists 112 suppliers of Emodin in China, United States, Germany, United Kingdom and 15 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Emodin in India?

1 supplier in India list Emodin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Emodin?

Suppliers quote Emodin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Emodin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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